7VUA
 
 | | Anaerobic hydroxyproline degradation involving C-N cleavage by a glycyl radical enzyme | | 分子名称: | (4S)-4-hydroxy-D-proline, HplG | | 著者 | Duan, Y, Lu, Q, Yuchi, Z, Zhang, Y. | | 登録日 | 2021-11-01 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.695 Å) | | 主引用文献 | Anaerobic Hydroxyproline Degradation Involving C-N Cleavage by a Glycyl Radical Enzyme.
J.Am.Chem.Soc., 144, 2022
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3T2Y
 | | Crystal structure of sulfide:quinone oxidoreductase His132Ala variant from Acidithiobacillus ferrooxidans with bound disulfide | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-23 | | 公開日 | 2012-05-16 | | 最終更新日 | 2012-06-13 | | 実験手法 | X-RAY DIFFRACTION (2.5001 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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6IVN
 | | Crystal structure of a membrane protein G264A | | 分子名称: | CHLORIDE ION, GLUTAMIC ACID, Ibestrophin, ... | | 著者 | Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. | | 登録日 | 2018-12-04 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
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3TFP
 | | Crystal Structure of Dehydrosqualene Synthase (CrtM) from S. aureus Complexed with BPH-1162 | | 分子名称: | 2-({2-chloro-6-[(2,4-dichlorophenyl)sulfanyl]benzyl}carbamoyl)benzoic acid, Dehydrosqualene synthase, MAGNESIUM ION | | 著者 | Lin, F.-Y, Liu, Y.-L, Zhang, Y, Oldfield, E. | | 登録日 | 2011-08-16 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics.
Chemmedchem, 7, 2012
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5XYU
 | | Small subunit of Mycobacterium smegmatis ribosome | | 分子名称: | 16S RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Li, Z, Zhang, Y, Zheng, L, Ge, X, Sanyal, S, Gao, N. | | 登録日 | 2017-07-10 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers.
Protein Cell, 9, 2018
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6IVL
 | | Crystal structure of a membrane protein L259A | | 分子名称: | ACETIC ACID, CHLORIDE ION, Ibestrophin, ... | | 著者 | Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. | | 登録日 | 2018-12-04 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
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6IVJ
 | | Crystal structure of a membrane protein G18A | | 分子名称: | ACETIC ACID, CHLORIDE ION, Ibestrophin, ... | | 著者 | Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. | | 登録日 | 2018-12-04 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
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3SXI
 | | Crystal structure of sulfide:quinone oxidoreductase Cys128Ala variant from Acidithiobacillus ferrooxidans complexed with decylubiquinone | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-14 | | 公開日 | 2012-05-16 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1792 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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5XYM
 | | Large subunit of Mycobacterium smegmatis | | 分子名称: | 23S RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Li, Z, Ge, X, Zhang, Y, Zheng, L, Sanyal, S, Gao, N. | | 登録日 | 2017-07-09 | | 公開日 | 2017-09-27 | | 最終更新日 | 2018-04-11 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers.
Protein Cell, 9, 2018
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3T2K
 | | Crystal structure of sulfide:quinone oxidoreductase Cys128Ala variant from Acidithiobacillus ferrooxidans with bound trisulfane | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-22 | | 公開日 | 2012-05-16 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3501 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3T31
 | | Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans in complex with decylubiquinone | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Cherney, M.M, Zhang, Y, Solomonson, M, Weiner, J.H, James, M.N. | | 登録日 | 2011-07-24 | | 公開日 | 2011-08-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans: insights into sulfidotrophic respiration and detoxification.
J.Mol.Biol., 398, 2010
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3T0K
 | | Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans with bound trisulfide and decylubiquinone | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-20 | | 公開日 | 2012-05-16 | | 最終更新日 | 2014-05-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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7EGS
 | | The crystal structure of lobe domain of E. coli RNA polymerase complexed with the C-terminal domain of UvrD | | 分子名称: | DNA helicase II, DNA-directed RNA polymerase subunit beta, GLYCEROL | | 著者 | Zheng, F, Shen, L, Li, L, Zhang, Y. | | 登録日 | 2021-03-26 | | 公開日 | 2022-04-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crucial role and mechanism of transcription-coupled DNA repair in bacteria.
Nature, 604, 2022
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7EGT
 | | The crystal structure of the C-terminal domain of T. thermophilus UvrD complexed with the N-terminal domain of UvrB | | 分子名称: | DNA helicase UvrD, UvrABC system protein B | | 著者 | Zheng, F, Shen, L, Li, L, Zhang, Y. | | 登録日 | 2021-03-26 | | 公開日 | 2022-04-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.581 Å) | | 主引用文献 | Crucial role and mechanism of transcription-coupled DNA repair in bacteria.
Nature, 604, 2022
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6J1N
 | | Anisodus acutangulus type III polyketide sythase AaPKS2 in complex with 4-carboxy-3-oxobutanoyl-CoA | | 分子名称: | (3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,19,21-tetraoxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide (non-preferred name), A. acutangulus PKS2 | | 著者 | Fang, C.L, Zhang, Y. | | 登録日 | 2018-12-28 | | 公開日 | 2019-09-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.532 Å) | | 主引用文献 | Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation.
Nat Commun, 10, 2019
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6JBQ
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5YIU
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5YIW
 | | Caulobacter crescentus GcrA DNA-binding domain (DBD) in complex with methylated dsDNA (crystal form 2) | | 分子名称: | (R,R)-2,3-BUTANEDIOL, Cell cycle regulatory protein GcrA, DNA (5'-D(*CP*CP*CP*TP*GP*(6MA)P*TP*TP*CP*GP*C)-3'), ... | | 著者 | Wu, X, Zhang, Y. | | 登録日 | 2017-10-06 | | 公開日 | 2018-03-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.551 Å) | | 主引用文献 | Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA.
Nucleic Acids Res., 46, 2018
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6JCX
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5YIV
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7EVM
 | | Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex | | 分子名称: | CHOLESTEROL, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | | 登録日 | 2021-05-21 | | 公開日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor.
Nat Commun, 12, 2021
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3T14
 | | Crystal structure of sulfide:quinone oxidoreductase Cys128Ala variant from Acidithiobacillus ferrooxidans with bound disulfide | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-21 | | 公開日 | 2012-05-16 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3TFV
 | | Crystal structure of dehydrosqualene synthase (crtm) from s. aureus complexed with bph-1154 | | 分子名称: | 5-bromo-2-{[3-(octyloxy)benzyl]sulfanyl}benzoic acid, Dehydrosqualene synthase, MAGNESIUM ION | | 著者 | Lin, F.-Y, Zhang, Y, Liu, Y.-L, Oldfield, E. | | 登録日 | 2011-08-16 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics.
Chemmedchem, 7, 2012
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7WL4
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor SLP-50 | | 分子名称: | Bromodomain-containing protein 4, ~{N}-[2-ethyl-6-(4-methylpiperazin-1-yl)-3-oxidanylidene-2,7-diazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaen-9-yl]-2,4-bis(fluoranyl)benzenesulfonamide | | 著者 | Zhang, C, Wang, C, Li, W, Zhang, Y, Xu, Y, Sun, L. | | 登録日 | 2022-01-12 | | 公開日 | 2022-08-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Design, synthesis, and anticancer evaluation of ammosamide B with pyrroloquinoline derivatives as novel BRD4 inhibitors.
Bioorg.Chem., 127, 2022
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7XIJ
 | | Crystal structure of CBP bromodomain liganded with Y08175 | | 分子名称: | 3-[(1-ethanoyl-5-methoxy-indol-3-yl)carbonylamino]-4-fluoranyl-5-(1-methylpyrazol-4-yl)benzoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Xiang, Q, Wang, C, Wu, T, Zhang, Y, Zhang, C, Luo, G, Wu, X, Shen, H, Xu, Y. | | 登録日 | 2022-04-13 | | 公開日 | 2022-06-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal structure of CBP bromodomain liganded with Y08175
To Be Published
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