4M0P
 
 | | Crystal structure of human PRS1 M115T mutant | | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | | 著者 | Chen, P, Teng, M, Li, X. | | 登録日 | 2013-08-01 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Plos One, 10, 2015
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8W9M
 | | Cryo-EM structure of the cyanobacterial nitrate transporter NrtBCD in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nitrate transport ATP-binding protein, ... | | 著者 | Li, B, Zhou, C.Z, Chen, Y.X, Jiang, Y.L. | | 登録日 | 2023-09-05 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Allosteric regulation of nitrate transporter NRT via the signaling protein PII.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8WM8
 | | Cryo-EM structure of cyanobacterial nitrate/nitrite transporter NrtBCD in complex with nitrate | | 分子名称: | NITRATE ION, Nitrate transport ATP-binding protein, Nitrate transport permease protein | | 著者 | Li, B, Zhou, C.Z, Chen, Y.X, Jiang, Y.L. | | 登録日 | 2023-10-03 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Allosteric regulation of nitrate transporter NRT via the signaling protein PII.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8WM7
 | | Cryo-EM structure of cyanobacterial nitrate/nitrite transporter NrtBCD in complex with signalling protein PII | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Nitrate transport ATP-binding protein, Nitrate transport permease protein, ... | | 著者 | Li, B, Zhou, C.Z, Chen, Y.X, Jiang, Y.L. | | 登録日 | 2023-10-03 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Allosteric regulation of nitrate transporter NRT via the signaling protein PII.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8YRH
 | | Complex of SARS-CoV-2 main protease and Rosmarinic acid | | 分子名称: | (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, 3C-like proteinase nsp5 | | 著者 | Wang, Q.S, Li, Q.H. | | 登録日 | 2024-03-21 | | 公開日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (1.841 Å) | | 主引用文献 | Structural basis of rosmarinic acid inhibitory mechanism on SARS-CoV-2 main protease.
Biochem.Biophys.Res.Commun., 724, 2024
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6LTN
 | | cryo-EM structure of C-terminal truncated human Pannexin1 | | 分子名称: | Pannexin-1 | | 著者 | Mou, L.Q, Ke, M, Xiao, Q.J, Wu, J.P, Deng, D. | | 登録日 | 2020-01-23 | | 公開日 | 2020-05-13 | | 最終更新日 | 2020-05-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis for gating mechanism of Pannexin 1 channel.
Cell Res., 30, 2020
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2MJV
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6IEG
 | | Crystal structure of human MTR4 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4, MAGNESIUM ION | | 著者 | Chen, J.Y, Yun, C.H. | | 登録日 | 2018-09-14 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | | 主引用文献 | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.
Genes Dev., 33, 2019
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4Q96
 | | CID of human RPRD1B in complex with an unmodified CTD peptide | | 分子名称: | RPB1-CTD, Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, ... | | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | | 登録日 | 2014-04-29 | | 公開日 | 2014-06-04 | | 最終更新日 | 2014-08-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
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5C6V
 | | Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis NINJA peptide | | 分子名称: | AFP homolog 2, ASPR2 protein | | 著者 | Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K. | | 登録日 | 2015-06-23 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
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5C7F
 | | Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA1 peptide | | 分子名称: | ASPR2 protein, Auxin-responsive protein IAA1, ZINC ION | | 著者 | Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K. | | 登録日 | 2015-06-24 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
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5C6Q
 | | Crystal structure of the apo TOPLESS related protein 2 (TPR2) N-terminal domain (1-209) from rice | | 分子名称: | ASPR2 protein, ZINC ION | | 著者 | Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K. | | 登録日 | 2015-06-23 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.251 Å) | | 主引用文献 | Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
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5YOV
 | | Crystal structure of BRD4-BD1 bound with hjp126 | | 分子名称: | (3~{R})-4-cyclopentyl-~{N}-(2,4-dimethylphenyl)-1,3-dimethyl-2-oxidanylidene-3~{H}-quinoxaline-6-carboxamide, Bromodomain-containing protein 4 | | 著者 | Xiong, B, Hu, J, Li, Y, Cao, D. | | 登録日 | 2017-10-31 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.451 Å) | | 主引用文献 | Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups.
Eur.J.Med.Chem., 150, 2018
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7L4V
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7FJO
 | | Cryo-EM structure of South African (B.1.351) SARS-CoV-2 spike glycoprotein in complex with three T6 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, T6 heavy chain, ... | | 著者 | Wang, X, Zhang, L, Zhang, S, Liang, Q. | | 登録日 | 2021-08-04 | | 公開日 | 2022-04-13 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants.
Iscience, 25, 2022
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7FJN
 | | Cryo-EM structure of South African (B.1.351) SARS-CoV-2 spike glycoprotein in complex with two T6 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Envelope glycoprotein, T6 heavy chain, ... | | 著者 | Wang, X, Zhang, L, Zhang, S, Liang, Q. | | 登録日 | 2021-08-04 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants.
Iscience, 25, 2022
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5C7E
 | | Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA10 peptide | | 分子名称: | ASPR2 protein, Auxin-responsive protein IAA10, ZINC ION | | 著者 | Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K. | | 登録日 | 2015-06-24 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
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8H1T
 | | Cryo-EM structure of BAP1-ASXL1 bound to chromatosome | | 分子名称: | DNA (187-MER), Histone H1.4, Histone H2A type 1-D, ... | | 著者 | Ge, W, Yu, C, Xu, R.M. | | 登録日 | 2022-10-04 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase.
Nature, 616, 2023
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6IEH
 | | Crystal structures of the hMTR4-NRDE2 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ... | | 著者 | Chen, J.Y, Yun, C.H. | | 登録日 | 2018-09-14 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.892 Å) | | 主引用文献 | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.
Genes Dev., 33, 2019
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8K0D
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8K0C
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3MET
 | | Crystal structure of SGF29 in complex with H3K4me2 | | 分子名称: | GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ... | | 著者 | Bian, C.B, Xu, C, Lam, R, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2010-03-31 | | 公開日 | 2010-04-28 | | 最終更新日 | 2011-08-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
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3G86
 | | Hepatitis C virus polymerase NS5B (BK 1-570) with thiazine inhibitor | | 分子名称: | N-{3-[6-fluoro-1-(4-fluorobenzyl)-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-1,1-dioxido-4H-1,4-benzothiazin-7-yl}methanesulfonamide, NICKEL (II) ION, RNA-directed RNA polymerase | | 著者 | Harris, S.F, Ghate, M. | | 登録日 | 2009-02-11 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure-activity relationships of benzothiazine-substituted quinolinediones
Bioorg.Med.Chem.Lett., 19, 2009
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3ME9
 | | Crystal structure of SGF29 in complex with H3K4me3 peptide | | 分子名称: | GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ... | | 著者 | Bian, C, Tempel, W, Xu, C, Guo, Y, Dong, A, Crombet, L, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2010-03-31 | | 公開日 | 2010-04-28 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
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3LX7
 | | Crystal structure of a Novel Tudor domain-containing protein SGF29 | | 分子名称: | SAGA-associated factor 29 homolog, SULFATE ION, UNKNOWN ATOM OR ION | | 著者 | Bian, C.B, Xu, C, Tempel, W, Lam, R, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J. | | 登録日 | 2010-02-24 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
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