8HKU
 
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8HKV
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8HL2
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8HL5
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8HL3
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8HGW
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8HGV
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4M49
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7S5S
 | | CTX-M-15 WT in complex with BLIP WT | | 分子名称: | Beta-lactamase, Beta-lactamase inhibitory protein | | 著者 | Lu, S, Palzkill, T, Hu, L.Y, Prasad, B.V.V, Sankaran, B. | | 登録日 | 2021-09-11 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M beta-lactamase drug-resistance enzymes.
Nat Commun, 13, 2022
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6Z45
 | | CDK9-Cyclin-T1 complex bound by compound 24 | | 分子名称: | (1~{S},3~{R})-3-acetamido-~{N}-[5-chloranyl-4-(5,5-dimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl]cyclohexane-1-carboxamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cyclin-T1, ... | | 著者 | Ferguson, A, Collie, G.W. | | 登録日 | 2020-05-22 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | | 主引用文献 | Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies.
J.Med.Chem., 63, 2020
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8HJ4
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1GR5
 | | Solution Structure of apo GroEL by Cryo-Electron microscopy | | 分子名称: | 60 KDA CHAPERONIN | | 著者 | Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R. | | 登録日 | 2001-12-14 | | 公開日 | 2002-01-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | ATP-Bound States of Groel Captured by Cryo-Electron Microscopy.
Cell(Cambridge,Mass.), 107, 2001
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7YSN
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7YSP
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7YSQ
 | | GTPgammaS Tube decorated with kinesin | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Tubulin alpha chain, ... | | 著者 | Zhou, J, Wang, H.-W. | | 登録日 | 2022-08-12 | | 公開日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | | 主引用文献 | Structural insights into the mechanism of GTP initiation of microtubule assembly.
Nat Commun, 14, 2023
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7YSO
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7YSR
 | | GTPgammaS MT decorated with kinesin | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Tubulin alpha chain, ... | | 著者 | Zhou, J, Wang, H.-W. | | 登録日 | 2022-08-12 | | 公開日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural insights into the mechanism of GTP initiation of microtubule assembly.
Nat Commun, 14, 2023
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5JI3
 | | HslUV complex | | 分子名称: | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV | | 著者 | Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V. | | 登録日 | 2016-04-21 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
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4X5Y
 | | Menin in complex with MI-503 | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-methyl-1-(1H-pyrazol-4-ylmethyl)-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile, ... | | 著者 | Pollock, J, Borkin, D, Cierpicki, T, Grembecka, J. | | 登録日 | 2014-12-06 | | 公開日 | 2015-04-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo.
Cancer Cell, 27, 2015
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5XOB
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8HLE
 | | Structure of DddY-DMSOP complex | | 分子名称: | 3-[dimethyl(oxidanyl)-$l^{4}-sulfanyl]propanoic acid, DMSP lyase DddY, ZINC ION | | 著者 | Peng, M, Li, C.Y, Zhang, Y.Z. | | 登録日 | 2022-11-30 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | DMSOP-cleaving enzymes are diverse and widely distributed in marine microorganisms.
Nat Microbiol, 8, 2023
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8HLF
 | | Crystal structure of DddK-DMSOP complex | | 分子名称: | 3-[dimethyl(oxidanyl)-$l^{4}-sulfanyl]propanoic acid, MANGANESE (II) ION, Novel protein with potential Cupin domain | | 著者 | Peng, M, Li, C.Y, Zhang, Y.Z. | | 登録日 | 2022-11-30 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | DMSOP-cleaving enzymes are diverse and widely distributed in marine microorganisms.
Nat Microbiol, 8, 2023
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5XNE
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8HFS
 | | The structure of LcnA, LciA, and the man-PTS of Lactococcus lactis | | 分子名称: | Bacteriocin lactococcin-A, Lactococcin-A immunity protein, Mannose-specific PTS system, ... | | 著者 | Wang, J.W. | | 登録日 | 2022-11-12 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Structural Basis of the Mechanisms of Action and Immunity of Lactococcin A, a Class IId Bacteriocin.
Appl.Environ.Microbiol., 89, 2023
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6RJK
 | | Structure of virulence factor SghA from Agrobacterium tumefaciens | | 分子名称: | Beta-glucosidase | | 著者 | Ye, F.Z, Wang, C, Chang, C.Q, Zhang, L.H, Gao, Y.G. | | 登録日 | 2019-04-27 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.922 Å) | | 主引用文献 | Agrobacteria reprogram virulence gene expression by controlled release of host-conjugated signals.
Proc.Natl.Acad.Sci.USA, 116, 2019
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