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6K7O
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Complex structure of LILRB4 and h128-3 antibody
分子名称: Leukocyte immunoglobulin-like receptor subfamily B member 4, h128-3 Fab heavy chain, h128-3 Fab light chain
著者Song, H, Chai, Y, Xu, X, Gao, F.G.
登録日2019-06-08
公開日2019-07-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development.
Cancer Immunol Res, 7, 2019
5Z9R
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BU of 5z9r by Molmil
NMNAT as a specific chaperone antagonizing pathological condensation of phosphorylated tau
分子名称: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
著者Dou, S, Ma, X, Li, D, Liu, C.
登録日2018-02-05
公開日2019-02-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Nicotinamide mononucleotide adenylyltransferase uses its NAD+substrate-binding site to chaperone phosphorylated Tau.
Elife, 9, 2020
7E39
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BU of 7e39 by Molmil
SARS-CoV-2 spike in complex with the Ab4 neutralizing antibody (State 3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Ab4, Light Chain of Ab4, ...
著者Liu, C.
登録日2021-02-08
公開日2021-09-01
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants.
Cell Discov, 7, 2021
7E3B
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BU of 7e3b by Molmil
SARS-Cov-2 spike in complex with the Ab5 neutralizing antibody (focused refinement on Fab-RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Ab5, Light Chain of Ab5, ...
著者Liu, C.
登録日2021-02-08
公開日2021-09-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants.
Cell Discov, 7, 2021
7E3C
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BU of 7e3c by Molmil
SARS-CoV-2 spike in complex with the Ab1 neutralizing antibody (focused refinement on Fab-RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Ab1, Light chain of Ab1, ...
著者Liu, C.
登録日2021-02-08
公開日2021-09-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants.
Cell Discov, 7, 2021
5WXY
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BU of 5wxy by Molmil
Crystal structure of Microcystis aeruginosa PCC 7806 aspartate racemase in complex with L-aspartate
分子名称: ASPARTIC ACID, McyF
著者Cao, D.D, Zhou, K, Jiang, Y.L, Zhou, C.Z.
登録日2017-01-09
公開日2018-01-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structural insights into the catalysis and substrate specificity of cyanobacterial aspartate racemase McyF.
Biochem.Biophys.Res.Commun., 514, 2019
5VTZ
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BU of 5vtz by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225Q/L226A mutant apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-05-18
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5WXX
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BU of 5wxx by Molmil
Crystal structure of Microcystis aeruginosa PCC 7806 aspartate racemase in complex with citrate
分子名称: CITRIC ACID, McyF
著者Cao, D.D, Zhou, K, Jiang, Y.L, Zhou, C.Z.
登録日2017-01-09
公開日2018-01-17
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into the catalysis and substrate specificity of cyanobacterial aspartate racemase McyF.
Biochem.Biophys.Res.Commun., 514, 2019
7WT9
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BU of 7wt9 by Molmil
SARS-CoV-2 Omicron variant spike RBD in complex with Fab 9A8
分子名称: Heavy chain of Fab 9A8, Light chain of Fab 9A8, Spike glycoprotein
著者Wang, X, Wang, L.
登録日2022-02-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD.
Cell Discov, 8, 2022
7WT7
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BU of 7wt7 by Molmil
SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 9A8, ...
著者Wang, X, Wang, L.
登録日2022-02-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD.
Cell Discov, 8, 2022
7WT8
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SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 9A8, ...
著者Wang, X, Wang, L.
登録日2022-02-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD.
Cell Discov, 8, 2022
5WKO
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BU of 5wko by Molmil
Crystal structure of antibody 27F3 recognizing the HA from A/California/04/2009 (H1N1) influenza virus
分子名称: Antibody 27F3 heavy chain, Antibody 27F3 light chain, Hemagglutinin
著者Wilson, I.A, Lang, S, Zhu, X.
登録日2017-07-25
公開日2017-10-25
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.492 Å)
主引用文献Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in VH1-69 Antibody Orientation on the HA Stem.
Cell Rep, 20, 2017
7XGO
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BU of 7xgo by Molmil
Human renin in complex with compound2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND
著者Kashima, A.
登録日2022-04-05
公開日2022-08-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of Novel 2-Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors.
Acs Med.Chem.Lett., 13, 2022
7XGK
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BU of 7xgk by Molmil
Human renin in complex with compound1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND
著者Kashima, A.
登録日2022-04-05
公開日2022-08-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Novel 2-Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors.
Acs Med.Chem.Lett., 13, 2022
7XGP
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BU of 7xgp by Molmil
Human renin in complex with compound3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND
著者Kashima, A.
登録日2022-04-05
公開日2022-09-07
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Discovery of SPH3127: A Novel, Highly Potent, and Orally Active Direct Renin Inhibitor.
J.Med.Chem., 65, 2022
5VTV
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BU of 5vtv by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225M/L226T/S228A mutant in complex with 3'-SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-05-18
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5VTQ
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BU of 5vtq by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225L/L226S mutant in complex with 3'-SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-05-17
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5VTX
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BU of 5vtx by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225M/L226T/S228A mutant apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-05-18
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5VTY
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BU of 5vty by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225Q/L226A mutant in complex with 3'-SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-05-18
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5VTU
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BU of 5vtu by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225L/L226S mutant apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-05-18
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5WXZ
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Crystal structure of Microcystis aeruginosa PCC 7806 aspartate racemase in complex with D-aspartate
分子名称: D-ASPARTIC ACID, McyF
著者Cao, D.D, Zhou, K, Jiang, Y.L, Zhou, C.Z.
登録日2017-01-09
公開日2018-01-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into the catalysis and substrate specificity of cyanobacterial aspartate racemase McyF.
Biochem.Biophys.Res.Commun., 514, 2019
8I71
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BU of 8i71 by Molmil
Hepatitis B virus core protein Y132A mutant in complex with Linvencorvir (RG7907), a Hepatitis B Virus (HBV) Core Protein Allosteric Modulator (CpAM)
分子名称: 3-[(8~{a}~{S})-7-[[5-ethoxycarbonyl-4-(3-fluoranyl-2-methyl-phenyl)-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-3-oxidanylidene-5,6,8,8~{a}-tetrahydro-1~{H}-imidazo[1,5-a]pyrazin-2-yl]-2,2-dimethyl-propanoic acid, CHLORIDE ION, Capsid protein, ...
著者Zhou, Z, Xu, Z.H.
登録日2023-01-30
公開日2023-03-22
最終更新日2023-04-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection.
J.Med.Chem., 66, 2023
7XPN
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Structure of the Spring Viraemia of Carp Virus Nucleoprotein
分子名称: Nucleoprotein
著者Wang, Z.X, Liu, B, Zhang, Y.A, Ouyang, S.Y.
登録日2022-05-04
公開日2023-05-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Structure of the Spring Viraemia of Carp Virus Ribonucleoprotein Complex Reveals Its Assembly Mechanism and Application in Antiviral Drug Screening.
J.Virol., 97, 2023

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