8HYI
| Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine | 分子名称: | 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ... | 著者 | Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. | 登録日 | 2023-01-06 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Modulation of a conformational ensemble by a small molecule that inhibits key protein-protein interactions involved in cell adhesion. Protein Sci., 32, 2023
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6M5W
| Co-crystal structure of human serine hydroxymethyltransferase 1 in complex with Pyridoxal 5'-phosphate (PLP) and glycodeoxycholic acid | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCINE, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Ota, T, Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K, Sando, S. | 登録日 | 2020-03-11 | 公開日 | 2021-01-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate. Iscience, 24, 2021
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6M5D
| Human serum albumin (apo form) | 分子名称: | PHOSPHATE ION, Serum albumin | 著者 | Ito, S, Senoo, A, Nagatoishi, S, Yamamoto, M, Tsumoto, K, Wakui, N. | 登録日 | 2020-03-10 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Basis for the Binding Mechanism of Human Serum Albumin Complexed with Cyclic Peptide Dalbavancin. J.Med.Chem., 63, 2020
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3VUA
| Apo IsdH-NEAT3 in space group P3121 at a resolution of 1.85 A | 分子名称: | ACETATE ION, GLYCEROL, Iron-regulated surface determinant protein H, ... | 著者 | Vu, N.T, Caaveiro, J.M.M, Moriwaki, Y, Tsumoto, K. | 登録日 | 2012-06-26 | 公開日 | 2013-06-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin To be Published
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5Y78
| Crystal structure of the triose-phosphate/phosphate translocator in complex with inorganic phosphate | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PHOSPHATE ION, Putative hexose phosphate translocator | 著者 | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | 登録日 | 2017-08-16 | 公開日 | 2017-10-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
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5Y79
| Crystal structure of the triose-phosphate/phosphate translocator in complex with 3-phosphoglycerate | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-PHOSPHOGLYCERIC ACID, CITRATE ANION, ... | 著者 | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | 登録日 | 2017-08-16 | 公開日 | 2017-10-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
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4P35
| Crystal structure of DJ-1 with Zinc(II) bound (crystal I) | 分子名称: | CHLORIDE ION, GLYCEROL, Protein DJ-1, ... | 著者 | Tashiro, S, Wu, C.-X, Hoang, Q.Q, Caaveiro, J.M.M, Tsumoto, K. | 登録日 | 2014-03-05 | 公開日 | 2014-04-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1. Biochemistry, 53, 2014
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4P2G
| Crystal structure of DJ-1 in sulfinic acid form (aged crystal) | 分子名称: | 1,2-ETHANEDIOL, PENTAETHYLENE GLYCOL, Protein DJ-1 | 著者 | Tashiro, S, Wu, C.-X, Hoang, Q.Q, Caaveiro, J.M.M, Tsumoto, K. | 登録日 | 2014-03-04 | 公開日 | 2014-04-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1. Biochemistry, 53, 2014
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4P36
| Crystal structure of DJ-1 With Zn(II) bound (crystal 2) | 分子名称: | 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, Protein DJ-1, ZINC ION | 著者 | Tashiro, S, Wu, C.-X, Hoang, Q.Q, Caaveiro, J.M.M, Tsumoto, K. | 登録日 | 2014-03-05 | 公開日 | 2014-04-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.182 Å) | 主引用文献 | Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1. Biochemistry, 53, 2014
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4P34
| Crystal structure of DJ-1 in sulfenic acid form (fresh crystal) | 分子名称: | PENTAETHYLENE GLYCOL, Protein DJ-1 | 著者 | Tashiro, S, Wu, C.-X, Hoang, Q.Q, Caaveiro, J.M.M, Tsumoto, K. | 登録日 | 2014-03-05 | 公開日 | 2014-04-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1. Biochemistry, 53, 2014
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1J1P
| Crystal structure of HyHEL-10 Fv mutant LS91A complexed with hen egg white lysozyme | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | 著者 | Yokota, A, Tsumoto, K, Shiroishi, M, Kondo, H, Kumagai, I. | 登録日 | 2002-12-13 | 公開日 | 2003-01-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Role of Hydrogen Bonding via Interfacial Water Molecules in Antigen-Antibody Complexation. THE HyHEL-10-HEL INTERACTION J.BIOL.CHEM., 278, 2003
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1J08
| Crystal structure of glutaredoxin-like protein from Pyrococcus horikoshii | 分子名称: | glutaredoxin-like protein | 著者 | Tanaka, Y, Tanabe, E, Tsumoto, K, Kumagai, I, Yao, M, Tanaka, I. | 登録日 | 2002-11-11 | 公開日 | 2003-05-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Protein disulfide isomerase from hyperthermophile as an additives of refolding of an immunoglobulin-folded protein To be Published
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1J1O
| Crystal Structure of HyHEL-10 Fv mutant LY50F complexed with hen egg white lysozyme | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | 著者 | Yokota, A, Tsumoto, K, Shiroishi, M, Kondo, H, Kumagai, I. | 登録日 | 2002-12-13 | 公開日 | 2003-01-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Role of Hydrogen Bonding via Interfacial Water Molecules in Antigen-Antibody Complexation. THE HyHEL-10-HEL INTERACTION J.BIOL.CHEM., 278, 2003
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1J1X
| Crystal Structure of HyHEL-10 Fv mutant LS93A complexed with hen egg white lysozyme | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | 著者 | Yokota, A, Tsumoto, K, Shiroishi, M, Kondo, H, Kumagai, I. | 登録日 | 2002-12-20 | 公開日 | 2003-01-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Role of Hydrogen Bonding via Interfacial Water Molecules in Antigen-Antibody Complexation. THE HyHEL-10-HEL INTERACTION J.BIOL.CHEM., 278, 2003
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1J2V
| Crystal Structure of CutA1 from Pyrococcus Horikoshii | 分子名称: | 102AA long hypothetical periplasmic divalent cation tolerance protein CUTA | 著者 | Tanaka, Y, Sakai, N, Yasutake, Y, Yao, M, Tsumoto, K, Kumagai, I, Tanaka, I. | 登録日 | 2003-01-11 | 公開日 | 2004-01-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural implications for heavy metal-induced reversible assembly and aggregation of a protein: the case of Pyrococcus horikoshii CutA. Febs Lett., 556, 2004
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1UA6
| Crystal structure of HYHEL-10 FV MUTANT SFSF complexed with HEN EGG WHITE LYSOZYME complex | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | 著者 | Kumagai, I, Nishimiya, Y, Kondo, H, Tsumoto, K. | 登録日 | 2003-02-28 | 公開日 | 2004-03-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural consequences of target epitope-directed functional alteration of an antibody. The case of anti-hen lysozyme antibody, HyHEL-10 J.Biol.Chem., 278, 2003
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1UD9
| Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) Homolog From Sulfolobus tokodaii | 分子名称: | DNA polymerase sliding clamp A, ZINC ION | 著者 | Tanabe, E, Yasutake, Y, Tanaka, Y, Yao, M, Tsumoto, K, Kumagai, I, Tanaka, I. | 登録日 | 2003-04-28 | 公開日 | 2004-06-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) Homolog From Sulfolobus tokodaii To be published
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1J05
| The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment | 分子名称: | GLYCEROL, PHOSPHATE ION, anti-CEA mAb T84.66, ... | 著者 | Kondo, H, Nishimura, Y, Shiroishi, M, Asano, R, Noro, N, Tsumoto, K, Kumagai, I. | 登録日 | 2002-11-01 | 公開日 | 2003-12-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment To be Published
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1UKU
| Crystal Structure of Pyrococcus horikoshii CutA1 Complexed with Cu2+ | 分子名称: | COPPER (II) ION, periplasmic divalent cation tolerance protein CutA | 著者 | Tanaka, Y, Yasutake, Y, Yao, M, Sakai, N, Tanaka, I, Tsumoto, K, Kumagai, I. | 登録日 | 2003-09-01 | 公開日 | 2004-01-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural implications for heavy metal-induced reversible assembly and aggregation of a protein: the case of Pyrococcus horikoshii CutA. Febs Lett., 556, 2004
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1UMJ
| Crystal structure of Pyrococcus horikoshii CutA in the presence of 3M guanidine hydrochloride | 分子名称: | GUANIDINE, periplasmic divalent cation tolerance protein CutA | 著者 | Tanaka, Y, Tsumoto, K, Yasutake, Y, Sakai, N, Yao, M, Tanaka, I, Kumagai, I. | 登録日 | 2003-10-02 | 公開日 | 2004-10-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural evidence for guanidine-protein side chain interactions: crystal structure of CutA from Pyrococcus horikoshii in 3M guanidine hydrochloride Biochem.Biophys.Res.Commun., 323, 2004
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1VBF
| Crystal structure of protein L-isoaspartate O-methyltransferase homologue from Sulfolobus tokodaii | 分子名称: | 231aa long hypothetical protein-L-isoaspartate O-methyltransferase | 著者 | Tanaka, Y, Tsumoto, K, Yasutake, Y, Umetsu, M, Yao, M, Tanaka, I, Fukada, H, Kumagai, I. | 登録日 | 2004-02-25 | 公開日 | 2004-08-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | How Oligomerization Contributes to the Thermostability of an Archaeon Protein: PROTEIN L-ISOASPARTYL-O-METHYLTRANSFERASE FROM SULFOLOBUS TOKODAII J.Biol.Chem., 279, 2004
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1UAC
| Crystal Structure of HYHEL-10 FV MUTANT SFSF Complexed with TURKEY WHITE LYSOZYME | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | 著者 | Kumagai, I, Nishimiya, Y, Kondo, H, Tsumoto, K. | 登録日 | 2003-03-08 | 公開日 | 2004-03-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural consequences of target epitope-directed functional alteration of an antibody. The case of anti-hen lysozyme antibody, HyHEL-10 J.BIOL.CHEM., 278, 2003
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1VE0
| Crystal structure of uncharacterized protein ST2072 from Sulfolobus tokodaii | 分子名称: | SULFATE ION, ZINC ION, hypothetical protein (ST2072) | 著者 | Tanabe, E, Horiike, Y, Tsumoto, K, Yasutake, Y, Yao, M, Tanaka, I, Kumagai, I. | 登録日 | 2004-03-26 | 公開日 | 2005-03-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the uncharacterized protein ST2072 from Sulfolobus tokodaii To be Published
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7CME
| Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor) | 分子名称: | 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ... | 著者 | Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. | 登録日 | 2020-07-27 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion Commun Biol, 4, 2021
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7CMF
| Crystal structure of human P-cadherin REC12 (monomer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor) | 分子名称: | 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3 | 著者 | Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. | 登録日 | 2020-07-27 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion Commun Biol, 4, 2021
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