2V74
 
 | | Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), in complex with S-adenosyl-homocysteine | | 分子名称: | HISTONE-ARGININE METHYLTRANSFERASE CARM1, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Yue, W.W, Hassler, M, Roe, S.M, Thompson-Vale, V, Pearl, L.H. | | 登録日 | 2007-07-26 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Insights Into Histone Code Syntax from Structural and Biochemical Studies of Carm1 Methyltransferase
Embo J., 26, 2007
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2V7E
 | | Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), unliganded | | 分子名称: | HISTONE-ARGININE METHYLTRANSFERASE CARM1, MERCURY (II) ION | | 著者 | Yue, W.W, Hassler, M, Roe, S.M, Thompson-Vale, V, Pearl, L.H. | | 登録日 | 2007-07-30 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Insights Into Histone Code Syntax from Structural and Biochemical Studies of Carm1 Methyltransferase
Embo J., 26, 2007
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2VXC
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2W2T
 | | Rac2 (G12V) in complex with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 | | 著者 | Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H. | | 登録日 | 2008-11-04 | | 公開日 | 2009-05-05 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
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2W2V
 | | Rac2 (G12V) in complex with GTPgS | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 | | 著者 | Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H. | | 登録日 | 2008-11-04 | | 公開日 | 2009-05-05 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
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2WM9
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2VXB
 | | Structure of the Crb2-BRCT2 domain | | 分子名称: | DNA REPAIR PROTEIN RHP9, PRASEODYMIUM ION | | 著者 | Kilkenny, M.L, Roe, S.M, Pearl, L.H. | | 登録日 | 2008-07-03 | | 公開日 | 2008-08-12 | | 最終更新日 | 2019-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and Functional Analysis of the Crb2-Brct2 Domain Reveals Distinct Roles in Checkpoint Signaling and DNA Damage Repair.
Genes Dev., 22, 2008
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2W2W
 | | PLCg2 Split Pleckstrin Homology (PH) Domain | | 分子名称: | 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2 | | 著者 | Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H. | | 登録日 | 2008-11-04 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
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2W42
 | | THE STRUCTURE OF A PIWI PROTEIN FROM ARCHAEOGLOBUS FULGIDUS COMPLEXED WITH A 16NT DNA DUPLEX. | | 分子名称: | 5'-D(*GP*TP*CP*GP*AP*AP*TP*TP)-3', 5'-D(*TP*TP*CP*GP*AP*CP*GP*CP)-3', MANGANESE (II) ION, ... | | 著者 | Parker, J.S, Roe, S.M, Barford, D. | | 登録日 | 2008-11-19 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Enhancement of the Seed-Target Recognition Step in RNA Silencing by a Piwi-Mid Domain Protein
Mol.Cell, 33, 2009
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2WMN
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2WMO
 | | Structure of the complex between DOCK9 and Cdc42. | | 分子名称: | CELL DIVISION CONTROL PROTEIN 42 HOMOLOG, DEDICATOR OF CYTOKINESIS PROTEIN 9, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Yang, J, Roe, S.M, Barford, D. | | 登録日 | 2009-07-02 | | 公開日 | 2009-09-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Activation of Rho Gtpases by Dock Exchange Factors is Mediated by a Nucleotide Sensor.
Science, 325, 2009
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2W2X
 | | Complex of Rac2 and PLCg2 spPH Domain | | 分子名称: | 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H. | | 登録日 | 2008-11-04 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
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2WT8
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2XX4
 | | Macrolactone Inhibitor bound to HSP90 N-term | | 分子名称: | (E)-ETHYL 13-CHLORO-14,16-DIHYDROXY-1,11-DIOXO-1,2,3,4,7,8,9,10,11,12-DECAHYDROBENZO[C][1]AZACYCLOTETRADECINE-10-CARBOXYLATE, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 | | 著者 | Moody, C.J, Prodromou, C, Pearl, L.H, Roe, S.M. | | 登録日 | 2010-11-08 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | | 主引用文献 | Targeting the Hsp90 Molecular Chaperone with Novel Macrolactams. Synthesis, Structural, Binding, and Cellular Studies.
Acs Chem.Biol., 6, 2011
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2XX5
 | | Macrolactone Inhibitor bound to HSP90 N-term | | 分子名称: | (5E,10R)-N-BENZYL-13-CHLORO-14,16-DIHYDROXY-1,11-DIOXO-1,2,3,4,7,8,9,10,11,12-DECAHYDRO-2-BENZAZACYCLOTETRADECINE-10-CARBOXAMIDE, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GLYCEROL | | 著者 | Moody, C.J, Prodromou, C, Pearl, L.H, Roe, S.M. | | 登録日 | 2010-11-08 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Targeting the Hsp90 Molecular Chaperone with Novel Macrolactams. Synthesis, Structural, Binding, and Cellular Studies.
Acs Chem.Biol., 6, 2011
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2XX2
 | | Macrolactone Inhibitor bound to HSP90 N-term | | 分子名称: | (5E)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-2-BENZAZACYCLOTETRADECINE-1,11(2H,12H)-DIONE, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GLYCEROL | | 著者 | Moody, C.J, Prodromou, C, Pearl, L.H, Roe, S.M. | | 登録日 | 2010-11-08 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Targeting the Hsp90 Molecular Chaperone with Novel Macrolactams. Synthesis, Structural, Binding, and Cellular Studies.
Acs Chem.Biol., 6, 2011
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2YLJ
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1HFO
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7AUD
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7AUC
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1WAO
 | | PP5 structure | | 分子名称: | MANGANESE (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE 5 | | 著者 | Barford, D. | | 登録日 | 2004-10-27 | | 公開日 | 2005-02-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Molecular Basis for Tpr Domain-Mediated Regulation of Protein Phosphatase 5
Embo J., 24, 2005
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4V8R
 | | The crystal structures of the eukaryotic chaperonin CCT reveal its functional partitioning | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Kalisman, N, Schroder, G.F, Levitt, M. | | 登録日 | 2012-03-28 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | The Crystal Structures of the Eukaryotic Chaperonin Cct Reveal its Functional Partitioning
Structure, 21, 2013
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4V94
 | | Molecular architecture of the eukaryotic chaperonin TRiC/CCT derived by a combination of chemical crosslinking and mass-spectrometry, XL-MS | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Leitner, A, Joachimiak, L.A, Bracher, A, Walzthoeni, T, Chen, B, Monkemeyer, L, Pechmann, S, Holmes, S, Cong, Y, Ma, B, Ludtke, S, Chiu, W, Hartl, F.U, Aebersold, R, Frydman, J. | | 登録日 | 2012-01-11 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT.
Structure, 20, 2012
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1QAD
 | | Crystal Structure of the C-Terminal SH2 Domain of the P85 alpha Regulatory Subunit of Phosphoinositide 3-Kinase: An SH2 domain mimicking its own substrate | | 分子名称: | PI3-KINASE P85 ALPHA SUBUNIT | | 著者 | Hoedemaeker, P.J, Siegal, G, Roe, M, Driscoll, P.C, Abrahams, J.P.A. | | 登録日 | 1999-02-26 | | 公開日 | 1999-10-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the C-terminal SH2 domain of the p85alpha regulatory subunit of phosphoinositide 3-kinase: an SH2 domain mimicking its own substrate.
J.Mol.Biol., 292, 1999
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1CNR
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