2V74
Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), in complex with S-adenosyl-homocysteine
Summary for 2V74
Entry DOI | 10.2210/pdb2v74/pdb |
Descriptor | HISTONE-ARGININE METHYLTRANSFERASE CARM1, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total) |
Functional Keywords | arginine methyltransferase, s-adenosyl-l-methionine, transcription regulation, alternative splicing, histone modification, co- activator, methyltransferase, chromatin regulator, nucleus, cytoplasm, transferase, transcription |
Biological source | MUS MUSCULUS (MOUSE) |
Cellular location | Nucleus: Q9WVG6 |
Total number of polymer chains | 4 |
Total formula weight | 157955.97 |
Authors | Yue, W.W.,Hassler, M.,Roe, S.M.,Thompson-Vale, V.,Pearl, L.H. (deposition date: 2007-07-26, release date: 2007-10-02, Last modification date: 2024-02-14) |
Primary citation | Yue, W.W.,Hassler, M.,Roe, S.M.,Thompson-Vale, V.,Pearl, L.H. Insights Into Histone Code Syntax from Structural and Biochemical Studies of Carm1 Methyltransferase Embo J., 26:4402-, 2007 Cited by PubMed: 17882261DOI: 10.1038/SJ.EMBOJ.7601856 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report