2V74

Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), in complex with S-adenosyl-homocysteine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (B, D, F, H)	HISTONE-ARGININE METHYLTRANSFERASE CARM1	polymer	346	39104.6	4	UniProt (Q9WVG6) Pfam (PF06325) Pfam (PF22528)	MUS MUSCULUS (MOUSE)	PROTEIN ARGININE N-METHYLTRANSFERASE, COACTIVATOR-ASSOCIATED ARGININE METHYLTRANSFERASE 1, COACTIVATOR ASSOCIATED ARGININE METHYLTRANSFERASE 1
2	E, F, G, H (B, D, F, H)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	4	Chemie (SAH)
3	I, J, K, L (B, D, F, H)	water	water		18.0	261	Chemie (HOH)

Sequence modifications

B, D, F, H: 145 - 146 (PDB: 2V74)
B, D, F, H: 147 - 490 (UniProt: Q9WVG6)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	156418.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1537.6
All*	Total formula weight	157956.0

*Water molecules are not included.