2W2T

Rac2 (G12V) in complex with GDP

Summary for 2W2T

• Entry DOI: 10.2210/pdb2w2t/pdb
• Related: 1DS6
• Descriptor: RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: signaling protein, phospholipase c, phosphoinositides, rho gtpases, rac signaling protein
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 20777.80

Authors

Opaleye, O.,Bunney, T.D.,Roe, S.M.,Pearl, L.H. (deposition date: 2008-11-04, release date: 2009-05-05, Last modification date: 2019-05-15)

• Primary citation: Bunney, T.D.,Opaleye, O.,Roe, S.M.,Vatter, P.,Baxendale, R.W.,Walliser, C.,Everett, K.L.,Josephs, M.B.,Christow, C.,Rodrigues-Lima, F.,Gierschik, P.,Pearl, L.H.,Katan, M.; Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.; Mol.Cell, 34:223-, 2009; PubMed: 19394299; DOI: 10.1016/J.MOLCEL.2009.02.023

Experimental method

X-RAY DIFFRACTION (1.95 Å)