8CIX
 
 | | DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Griselimycin. | | 分子名称: | ACETATE ION, Beta sliding clamp, CALCIUM ION, ... | | 著者 | Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R. | | 登録日 | 2023-02-11 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins.
Nat Commun, 15, 2024
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7QY3
 | | Crystal structure of the halohydrin dehalogenase HheG D114C mutant cross-linked with BMOE | | 分子名称: | 1,1'-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), Putative oxidoreductase, SULFATE ION | | 著者 | Henke, S, Blankenfeldt, W, Schallmey, A. | | 登録日 | 2022-01-27 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Biocatalytically active and stable cross-linked enzyme crystals of halohydrin dehalogenase HheG by protein engineering
Chemcatchem, 2022
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6Q7U
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7QA0
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6Q7W
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7QA3
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7QAV
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7OC5
 | | Alpha-humulene synthase AsR6 from Sarocladium schorii | | 分子名称: | Alpha-humulene synthase AsR6, MAGNESIUM ION, ZINC ION | | 著者 | Schotte, C, Lukat, P, Deuschmann, A, Blankenfeldt, W, Cox, R.J. | | 登録日 | 2021-04-26 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Understanding and Engineering the Stereoselectivity of Humulene Synthase.
Angew.Chem.Int.Ed.Engl., 60, 2021
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6Q7V
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7OC6
 | | Selenomethionine derivative of alpha-humulene synthase AsR6 from Sarocladium schorii | | 分子名称: | Alpha-humulene synthase asR6, GLYCEROL, SULFATE ION, ... | | 著者 | Schotte, C, Lukat, P, Deuschmann, A, Blankenfeldt, W, Cox, R.J. | | 登録日 | 2021-04-26 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-09-15 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Understanding and Engineering the Stereoselectivity of Humulene Synthase.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7OC4
 | | Alpha-humulene synthase AsR6 from Sarocladium schorii in complex with thiolodiphosphate and a cyclized reaction product. | | 分子名称: | (1E,4E,8E)-2,6,6,9-Tetramethyl-1,4-8-cycloundecatriene, (R,R)-2,3-BUTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | 著者 | Schotte, C, Lukat, P, Deuschmann, A, Blankenfeldt, W, Cox, R.J. | | 登録日 | 2021-04-26 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Understanding and Engineering the Stereoselectivity of Humulene Synthase.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7OZQ
 | | Crystal structure of archaeal L7Ae bound to eukaryotic kink-loop | | 分子名称: | 50S ribosomal protein L7Ae, ACETATE ION, CALCIUM ION, ... | | 著者 | Hoefler, S, Lukat, P, Carlomagno, T, Blankenfeldt, W. | | 登録日 | 2021-06-28 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Eukaryotic Box C/D methylation machinery has two non-symmetric protein assembly sites.
Sci Rep, 11, 2021
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1KD0
 | | Crystal Structure of beta-methylaspartase from Clostridium tetanomorphum. Apo-structure. | | 分子名称: | 1,2-ETHANEDIOL, beta-methylaspartase | | 著者 | Asuncion, M, Blankenfeldt, W, Barlow, J.N, Gani, D, Naismith, J.H. | | 登録日 | 2001-11-12 | | 公開日 | 2001-12-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step.
J.Biol.Chem., 277, 2002
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1KCZ
 | | Crystal Structure of beta-methylaspartase from Clostridium tetanomorphum. Mg-complex. | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, beta-methylaspartase | | 著者 | Asuncion, M, Blankenfeldt, W, Barlow, J.N, Gani, D, Naismith, J.H. | | 登録日 | 2001-11-12 | | 公開日 | 2001-12-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step.
J.Biol.Chem., 277, 2002
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2KTT
 | | Solution Structure of a Covalently Bound Pyrrolo[2,1-c][1,4]benzodiazepine-Benzimidazole Hybrid to a 10mer DNA Duplex | | 分子名称: | (11aS)-7-methoxy-8-(3-{4-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]phenoxy}propoxy)-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 5'-D(*AP*AP*CP*AP*AP*TP*TP*GP*TP*T)-3' | | 著者 | Rettig, M, Weingarth, M, Langel, W, Kamal, A, Kumar, P.P, Weisz, K. | | 登録日 | 2010-02-08 | | 公開日 | 2010-03-09 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a covalently bound pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole hybrid to a 10mer DNA duplex.
Biochemistry, 48, 2009
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2KY7
 | | NMR Structural Studies on the Covalent DNA Binding of a Pyrrolobenzodiazepine-Naphthalimide Conjugate | | 分子名称: | 2-{2-[4-(3-{[(11aS)-7-methoxy-5-oxo-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepin-8-yl]oxy}propyl)piperazin-1-yl]ethyl}-1H-benzo[de]isoquinoline-1,3(2H)-dione, 5'-D(*AP*AP*CP*AP*AP*TP*TP*GP*TP*T)-3' | | 著者 | Rettig, M, Langel, W, Kamal, A, Weisz, K. | | 登録日 | 2010-05-17 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structural studies on the covalent DNA binding of a pyrrolobenzodiazepine-naphthalimide conjugate
Org.Biomol.Chem., 8, 2010
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6YA1
 | | Zinc metalloprotease ProA | | 分子名称: | ACETATE ION, CALCIUM ION, ZINC ION, ... | | 著者 | Schmelz, S, Blankenfeldt, W. | | 登録日 | 2020-03-11 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation.
Cell.Microbiol., 23, 2021
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6YIZ
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2JKW
 | | Pseudoazurin M16F | | 分子名称: | COPPER (II) ION, PSEUDOAZURIN | | 著者 | Yanagisawa, S, Crowley, P.B, Firbank, S.J, Lawler, A.T, Hunter, D.M, McFarlane, W, Li, C, Kohzuma, T, Banfield, M.J, Dennison, C. | | 登録日 | 2008-09-01 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Pi-Interaction Tuning of the Active Site Properties of Metalloproteins.
J.Am.Chem.Soc., 130, 2008
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6YZE
 | | Zinc metalloprotease ProA from native source | | 分子名称: | ZINC ION, Zinc metalloproteinase | | 著者 | Schmelz, S, Blankenfeldt, W. | | 登録日 | 2020-05-06 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation.
Cell.Microbiol., 23, 2021
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6ZDT
 | | Crystal structure of eukaryotic Fibrillarin with Nop56 N-terminal domain | | 分子名称: | Nucleolar protein 56, rRNA 2'-O-methyltransferase fibrillarin | | 著者 | Hoefler, S, Lukat, P, Carlomagno, T, Blankenfeldt, W. | | 登録日 | 2020-06-15 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain.
Rna, 27, 2021
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5OE6
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6TUM
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6RTD
 | | Dihydro-heme d1 dehydrogenase NirN in complex with DHE | | 分子名称: | (R,R)-2,3-BUTANEDIOL, Cytochrome c, HEME C, ... | | 著者 | Kluenemann, T, Preuss, A, Layer, G, Blankenfeldt, W. | | 登録日 | 2019-05-23 | | 公開日 | 2019-06-19 | | 最終更新日 | 2019-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Crystal Structure of Dihydro-Heme d1Dehydrogenase NirN from Pseudomonas aeruginosa Reveals Amino Acid Residues Essential for Catalysis.
J.Mol.Biol., 431, 2019
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6RTE
 | | Dihydro-heme d1 dehydrogenase NirN in complex with DHE | | 分子名称: | (R,R)-2,3-BUTANEDIOL, Cytochrome c, HEME C | | 著者 | Kluenemann, T, Preuss, A, Layer, G, Blankenfeldt, W. | | 登録日 | 2019-05-23 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Crystal Structure of Dihydro-Heme d1Dehydrogenase NirN from Pseudomonas aeruginosa Reveals Amino Acid Residues Essential for Catalysis.
J.Mol.Biol., 431, 2019
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