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7TCA
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BU of 7tca by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike in complex with antibody A19-46.1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, ...
著者Zhou, T, Kwong, P.D.
登録日2021-12-23
公開日2022-03-30
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7U0D
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BU of 7u0d by Molmil
Local refinement of cryo-EM structure of the interface of the Omicron RBD in complex with antibodies B-182.1 and A19-46.1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-46.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ...
著者Zhou, T, kwong, P.D.
登録日2022-02-17
公開日2022-03-30
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7U9O
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BU of 7u9o by Molmil
SARS-CoV-2 spike trimer RBD in complex with Fab NE12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NE12 Fab heavy chain, NE12 Fab light chain, ...
著者Tsybovsky, Y, Kwong, P.D, Farci, P.
登録日2022-03-11
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
7TYZ
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BU of 7tyz by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DARPin FSR22, ...
著者Kwon, Y.D, Gorman, J, Kwong, P.D.
登録日2022-02-15
公開日2022-12-07
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
7U9P
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BU of 7u9p by Molmil
SARS-CoV-2 spike trimer RBD in complex with Fab NA8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NA8 Fab heavy chain, NA8 Fab light chain, ...
著者Tsybovsky, Y, Kwong, P.D, Farci, P.
登録日2022-03-11
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
7TZ0
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BU of 7tz0 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin (Local refinement of FSR22 and RBD)
分子名称: DARPin FSR22, Spike glycoprotein
著者Kwon, Y.D, Gorman, J, Kwong, P.D.
登録日2022-02-15
公開日2022-12-07
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (4.17 Å)
主引用文献A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
6P7H
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BU of 6p7h by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody DF2F-b.04 in complex with HIV fusion peptide (residue 512-519)
分子名称: Antibody DF2F-b.04 heavy chain, Antibody DF2F-b.04 light chain, HIV fusion peptide residues (512-519)
著者Xu, K, Liu, K, Wang, Y, Kwong, P.D.
登録日2019-06-05
公開日2020-06-10
実験手法X-RAY DIFFRACTION (1.782 Å)
主引用文献Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies
To Be Published
6P60
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BU of 6p60 by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody A12V163-a.02 in complex with HIV fusion peptide (residue 512-519)
分子名称: Antibody A12V163-a.02 heavy chain, Antibody A12V163-a.02 light chain, HIV fusion peptide residue 512-519
著者Xu, K, Liu, K, Kwong, P.D.
登録日2019-05-31
公開日2020-06-03
実験手法X-RAY DIFFRACTION (2.498 Å)
主引用文献Vaccine-elicited NHP FP-targeting neutralizing antibody A12V163-a.02 in complex with HIV fusion peptide (residue 512-519)
To Be Published
6P8D
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BU of 6p8d by Molmil
Vaccine-elicited murine FP-targeting antibody vFP6.01 in complex with HIV fusion peptide (residue 512-519)
分子名称: Antibody VFP6.01 heavy chain, Antibody VFP6.01 light chain, HIV fusion peptide residue 512-519
著者Xu, K, Liu, K, Wang, Y, Kwong, P.D.
登録日2019-06-07
公開日2020-06-10
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies
To Be Published
6PEF
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BU of 6pef by Molmil
Vaccine-elicited NHP FP-targeting antibody DF2F-a.01 in complex with HIV fusion peptide (residue 512-519)
分子名称: HIV fusion peptide residue 512-519, antibody DF2F-a.01 heavy chain, antibody DF2F-a.01 light chain
著者Xu, K, Liu, K, Wang, Y, Kwong, P.D.
登録日2019-06-20
公開日2020-06-24
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies
To Be Published
6PEC
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BU of 6pec by Molmil
Vaccine-elicited NHP FP-targeting antibody DF2F-e.01 in complex with HIV fusion peptide (residue 512-519)
分子名称: HIV-1 fusion peptide residue 512-519, antibody heavy chain, antibody light chain
著者Xu, K, Liu, K, Wang, Y, Kwong, P.D.
登録日2019-06-20
公開日2020-06-24
実験手法X-RAY DIFFRACTION (1.746 Å)
主引用文献Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies
To Be Published
6PDS
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BU of 6pds by Molmil
Vaccine-elicited NHP FP-targeting antibody 0PV-a.04 in complex with HIV fusion peptide (residue 512-519)
分子名称: HIV-1 fusion peptide residue 512-519, SULFATE ION, antibody 0PV-a.04 heavy chain, ...
著者Xu, K, Liu, K, Wang, Y, Kwong, P.D.
登録日2019-06-19
公開日2020-06-24
実験手法X-RAY DIFFRACTION (1.893 Å)
主引用文献Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies
To Be Published
6PDR
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BU of 6pdr by Molmil
Vaccine-elicited murine FP-targeting antibody vFP25.18 in complex with HIV fusion peptide (residue 512-519)
分子名称: HIV fusion peptide residue 512-519, antibody vFP25.18 heavy chain, antibody vFP25.18 light chain
著者Xu, K, Liu, K, Wang, Y, Kwong, P.D.
登録日2019-06-19
公開日2020-06-24
実験手法X-RAY DIFFRACTION (1.555 Å)
主引用文献Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies
To Be Published
8T5C
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BU of 8t5c by Molmil
Lassa GPC Trimer in complex with Fab 8.11G and nanobody D5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8.11G Heavy Chain, 8.11G Light Chain, ...
著者Gorman, J, Kwong, P.D.
登録日2023-06-13
公開日2024-01-03
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability.
Nat Commun, 15, 2024
6PDU
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BU of 6pdu by Molmil
Vaccine-elicited NHP FP-targeting antibody 13N024-a.01 in complex with HIV fusion peptide (residue 512-519)
分子名称: HIV-1 fusion peptide residue 512-519, antibody 13N024-a.01, heavy chain, ...
著者Xu, K, Liu, K, Wang, Y, Kwong, P.D.
登録日2019-06-19
公開日2020-06-24
実験手法X-RAY DIFFRACTION (1.953 Å)
主引用文献Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies
To Be Published
8T1G
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BU of 8t1g by Molmil
The crystal structure of hemagglutinin form a h7n9 influenza virus (a/shanghai/1/2013) in complex with antibody 1E11
分子名称: 1E11 Fab Heavy chain, 1E11 Fab Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhou, T, Kwong, P.D.
登録日2023-06-02
公開日2024-05-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The crystal structure of hemagglutinin form a h7n9 influenza virus (a/shanghai/1/2013) in complex with antibody 1E11
To Be Published
6Q0S
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BU of 6q0s by Molmil
Crystal Structure of RSV strain B18537 Prefusion-stabilized glycoprotein F Variant DS-Cav1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, SULFATE ION
著者Joyce, M.G, Bao, A, Kwong, P.D.
登録日2019-08-02
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B.
Pathog Immun, 4, 2019
6OT1
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BU of 6ot1 by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
分子名称: 0PV-b.01 heavy, 0PV-b.01 light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorman, J, Kwong, P.D.
登録日2019-05-02
公開日2019-08-07
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OSY
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BU of 6osy by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
分子名称: 0PV-a.01 Heavy, 0PV-a.01 Light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorman, J, Kwong, P.D.
登録日2019-05-02
公開日2019-07-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
8VUZ
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BU of 8vuz by Molmil
L5A7 Fab bound to 28H6E11 anti-idiotype Fab
分子名称: 28H6E11 Fab Heavy Chain, 28H6E11 Fab Light Chain, L5A7 Fab Heavy Chain, ...
著者Olia, A.S, Morano, N.C, Kwong, P.D.
登録日2024-01-30
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Anti-Idiotype Isolation of a Broad and Potent Influenza A Virus-Neutralizing Antibody
To Be Published
8VUE
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BU of 8vue by Molmil
L5A7 Fab bound to Indonesia2005 Hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
著者Olia, A.S, Gorman, J, Kwong, P.D.
登録日2024-01-29
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Anti-Idiotype Isolation of a Broad and Potent Influenza A Virus-Neutralizing Antibody
To Be Published
4YDK
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BU of 4ydk by Molmil
Crystal structure of broadly and potently neutralizing antibody C38-VRC16.01 in complex with HIV-1 clade AE strain 93TH057 gp120
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Zhou, T, Moquin, S, Zheng, A, Kwong, P.D.
登録日2015-02-22
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.051 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YFL
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BU of 4yfl by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 1B2530 in complex with HIV-1 clade A/E 93TH057 gp120
分子名称: 1B2530 Light chain, 1B2530 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Acharya, P, Zhou, T, Moquin, S, Kwong, P.D.
登録日2015-02-25
公開日2015-06-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.387 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4ZPV
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BU of 4zpv by Molmil
Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D12 Fab Heavy chain, D12 Fab light chain, ...
著者Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
登録日2015-05-08
公開日2015-10-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Evaluation of candidate vaccine approaches for MERS-CoV.
Nat Commun, 6, 2015
4ZPW
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BU of 4zpw by Molmil
Structure of unbound MERS-CoV spike receptor-binding domain (England1 strain).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Spike glycoprotein
著者Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
登録日2015-05-08
公開日2015-08-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.023 Å)
主引用文献Evaluation of candidate vaccine approaches for MERS-CoV.
Nat Commun, 6, 2015

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件を2024-06-12に公開中

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