3PSI
 
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7MQS
 | | The insulin receptor ectodomain in complex with three venom hybrid insulin molecules - asymmetric conformation | | 分子名称: | Insulin A chain, Insulin B chain, Isoform Short of Insulin receptor | | 著者 | Blakely, A.D, Xiong, X, Kim, J.H, Menting, J, Schafer, I.B, Schubert, H.L, Agrawal, R, Gutmann, T, Delaine, C, Zhang, Y, Artik, G.O, Merriman, A, Eckert, D, Lawrence, M.C, Coskun, U, Fisher, S.J, Forbes, B.E, Safavi-Hemami, H, Hill, C.P, Chou, D.H.C. | | 登録日 | 2021-05-06 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Symmetric and asymmetric receptor conformation continuum induced by a new insulin.
Nat.Chem.Biol., 18, 2022
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7MQO
 | | The insulin receptor ectodomain in complex with a venom hybrid insulin analog - "head" region | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, ... | | 著者 | Blakely, A.D, Xiong, X, Kim, J.H, Menting, J, Schafer, I.B, Schubert, H.L, Agrawal, R, Gutmann, T, Delaine, C, Zhang, Y, Artik, G.O, Merriman, A, Eckert, D, Lawrence, M.C, Coskun, U, Fisher, S.J, Forbes, B.E, Safavi-Hemami, H, Hill, C.P, Chou, D.H.C. | | 登録日 | 2021-05-06 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Symmetric and asymmetric receptor conformation continuum induced by a new insulin.
Nat.Chem.Biol., 18, 2022
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7MQR
 | | The insulin receptor ectodomain in complex with four venom hybrid insulins - symmetric conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | | 著者 | Blakely, A.D, Xiong, X, Kim, J.H, Menting, J, Schafer, I.B, Schubert, H.L, Agrawal, R, Gutmann, T, Delaine, C, Zhang, Y, Artik, G.O, Merriman, A, Eckert, D, Lawrence, M.C, Coskun, U, Fisher, S.J, Forbes, B.E, Safavi-Hemami, H, Hill, C.P, Chou, D.H.C. | | 登録日 | 2021-05-06 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Symmetric and asymmetric receptor conformation continuum induced by a new insulin.
Nat.Chem.Biol., 18, 2022
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3PSF
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7MHS
 | | Structure of p97 (subunits A to E) with substrate engaged | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Xu, Y, Han, H, Cooney, I, Hill, C.P, Shen, P.S. | | 登録日 | 2021-04-15 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Active conformation of the p97-p47 unfoldase complex.
Nat Commun, 13, 2022
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3PSK
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3OAK
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3NWH
 | | Crystal structure of BST2/Tetherin | | 分子名称: | Bone marrow stromal antigen 2 | | 著者 | Schubert, H.L, Zhai, Q, Hill, C.P. | | 登録日 | 2010-07-09 | | 公開日 | 2010-07-21 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3RBQ
 | | Co-crystal structure of human UNC119 (retina gene 4) and an N-terminal Transducin-alpha mimicking peptide | | 分子名称: | Guanine nucleotide-binding protein G(t) subunit alpha-1, Protein unc-119 homolog A | | 著者 | Constantine, R, Whitby, F.G, Hill, C.P, Baehr, W. | | 登録日 | 2011-03-29 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | UNC119 is required for G protein trafficking in sensory neurons.
Nat.Neurosci., 14, 2011
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1NV8
 | | N5-glutamine methyltransferase, HemK | | 分子名称: | N5-METHYLGLUTAMINE, S-ADENOSYLMETHIONINE, hemK protein | | 著者 | Schubert, H.L, Phillips, J.D, Hill, C.P. | | 登録日 | 2003-02-02 | | 公開日 | 2003-05-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures along the Catalytic Pathway of PrmC/HemK, an N(5)-Glutamine
AdoMet-Dependent Methyltransferase
Biochemistry, 42, 2003
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1FNT
 | | CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST IN COMPLEX WITH THE PROTEASOME ACTIVATOR PA26 FROM TRYPANOSOME BRUCEI AT 3.2 ANGSTROMS RESOLUTION | | 分子名称: | MAGNESIUM ION, PROTEASOME ACTIVATOR PROTEIN PA26, PROTEASOME COMPONENT C1, ... | | 著者 | Whitby, F.G, Masters, E, Kramer, L, Knowlton, J.R, Yao, Y, Wang, C.C, Hill, C.P. | | 登録日 | 2000-08-23 | | 公開日 | 2001-04-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for the activation of 20S proteasomes by 11S regulators.
Nature, 408, 2000
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1NV9
 | | HemK, apo structure | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, hemK protein | | 著者 | Schubert, H.L, Phillips, J.D, Hill, C.P. | | 登録日 | 2003-02-02 | | 公開日 | 2003-05-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.356 Å) | | 主引用文献 | Structures along the Catalytic Pathway of PrmC/HemK, an N(5)-Glutamine
AdoMet-Dependent Methyltransferase
Biochemistry, 42, 2003
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1QB7
 | | CRYSTAL STRUCTURES OF ADENINE PHOSPHORIBOSYLTRANSFERASE FROM LEISHMANIA DONOVANI. | | 分子名称: | ADENINE, ADENINE PHOSPHORIBOSYLTRANSFERASE, CITRIC ACID, ... | | 著者 | Phillips, C.L, Ullman, B, Brennan, R.G, Hill, C.P. | | 登録日 | 1999-04-30 | | 公開日 | 1999-07-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
EMBO J., 18, 1999
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2R0Y
 | | Structure of the Rsc4 tandem bromodomain in complex with an acetylated H3 peptide | | 分子名称: | Chromatin structure-remodeling complex protein RSC4, Histone H3 peptide | | 著者 | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | 登録日 | 2007-08-21 | | 公開日 | 2007-10-30 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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2R0S
 | | Crystal Structure of the Rsc4 tandem bromodomain | | 分子名称: | Chromatin structure-remodeling complex protein RSC4 | | 著者 | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | 登録日 | 2007-08-21 | | 公開日 | 2007-10-30 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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2R3C
 | | Structure of the gp41 N-peptide in complex with the HIV entry inhibitor PIE1 | | 分子名称: | CHLORIDE ION, HIV entry inhibitor PIE1, YTTRIUM (III) ION, ... | | 著者 | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | 登録日 | 2007-08-29 | | 公開日 | 2007-10-02 | | 最終更新日 | 2018-08-08 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2R5B
 | | Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7 | | 分子名称: | HIV entry inhibitor PIE7, SULFATE ION, gp41 N-peptide | | 著者 | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | 登録日 | 2007-09-03 | | 公開日 | 2007-10-02 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2R5D
 | | Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HIV entry inhibitor PIE7, ... | | 著者 | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | 登録日 | 2007-09-03 | | 公開日 | 2007-10-02 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2R0V
 | | Structure of the Rsc4 tandem bromodomain acetylated at K25 | | 分子名称: | Chromatin structure-remodeling complex protein RSC4, SULFATE ION | | 著者 | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | 登録日 | 2007-08-21 | | 公開日 | 2007-10-30 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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2R10
 | | Structure of an acetylated Rsc4 tandem bromodomain Histone Chimera | | 分子名称: | 1,2-ETHANEDIOL, Chromatin structure-remodeling complex protein RSC4, LINKER, ... | | 著者 | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | 登録日 | 2007-08-21 | | 公開日 | 2007-10-30 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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1YAU
 | | Structure of Archeabacterial 20S proteasome- PA26 complex | | 分子名称: | GLYCEROL, Proteasome alpha subunit, Proteasome beta subunit, ... | | 著者 | Forster, A, Masters, E.I, Whitby, F.G, Robinson, H, Hill, C.P. | | 登録日 | 2004-12-17 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.
Mol.Cell, 18, 2005
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1YAR
 | | Structure of Archeabacterial 20S proteasome mutant D9S- PA26 complex | | 分子名称: | GLYCEROL, Proteasome alpha subunit, Proteasome beta subunit, ... | | 著者 | Forster, A, Masters, E.I, Whitby, F.G, Robinson, H, Hill, C.P. | | 登録日 | 2004-12-17 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.
Mol.Cell, 18, 2005
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1YA7
 | | Implications for interactions of proteasome with PAN and PA700 from the 1.9 A structure of a proteasome-11S activator complex | | 分子名称: | GLYCEROL, Proteasome alpha subunit, Proteasome beta subunit, ... | | 著者 | Forster, A, Masters, E.I, Whitby, F.G, Robinson, H, Hill, C.P. | | 登録日 | 2004-12-17 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.
Mol.Cell, 18, 2005
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1Z3Y
 | | Structure of Gun4-1 from Thermosynechococcus elongatus | | 分子名称: | putative cytidylyltransferase | | 著者 | Davison, P.A, Schubert, H.L, Reid, J.D, Iorg, C.D, Robinson, H, Hill, C.P, Hunter, C.N. | | 登録日 | 2005-03-14 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Biochemical Characterization of Gun4 Suggests a Mechanism for Its Role in Chlorophyll Biosynthesis(,).
Biochemistry, 44, 2005
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