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Cryo-EM structure of octameric chicken CALHM1
分子名称:	Green fluorescent protein,CALHM1 chimera
著者	Syrjanen, J.L, Chou, T.H, Furukawa, H.
登録日	2019-12-17
公開日	2020-01-29
最終更新日	2020-11-11
実験手法	ELECTRON MICROSCOPY (3.63 Å)
主引用文献	Structure and assembly of calcium homeostasis modulator proteins. Nat.Struct.Mol.Biol., 27, 2020

6UZR

Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and homoquinolinic acid
分子名称:	3-(carboxymethyl)pyridine-2-carboxylic acid, GLYCEROL, GLYCINE, ...
著者	Wang, J.X, Furukawa, H.
登録日	2019-11-15
公開日	2020-01-29
最終更新日	2024-10-23
実験手法	X-RAY DIFFRACTION (1.87 Å)
主引用文献	Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nat Commun, 11, 2020

6VAK

Cryo-EM structure of human CALHM2
分子名称:	Calcium homeostasis modulator protein 2
著者	Syrjanen, J.L, Chou, T.H, Furukawa, H.
登録日	2019-12-17
公開日	2020-01-29
最終更新日	2024-10-16
実験手法	ELECTRON MICROSCOPY (3.48 Å)
主引用文献	Structure and assembly of calcium homeostasis modulator proteins. Nat.Struct.Mol.Biol., 27, 2020

6WHV

GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 2
分子名称:	(2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Chou, T, Tajima, N, Furukawa, H.
登録日	2020-04-08
公開日	2020-08-05
実験手法	ELECTRON MICROSCOPY (4.05 Å)
主引用文献	Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020

6WHS

GluN1b-GluN2B NMDA receptor in non-active 1 conformation at 3.95 angstrom resolution
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者	Chou, T, Tajima, N, Furukawa, H.
登録日	2020-04-08
公開日	2020-08-05
最終更新日	2024-10-16
実験手法	ELECTRON MICROSCOPY (4 Å)
主引用文献	Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020

6WI1

GluN1b-GluN2B NMDA receptor in active conformation stabilized by inter-GluN1b-GluN2B subunit cross-linking
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ...
著者	Chou, T, Tajima, N, Furukawa, H.
登録日	2020-04-08
公開日	2020-07-15
最終更新日	2024-10-30
実験手法	ELECTRON MICROSCOPY (3.62 Å)
主引用文献	Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020

6WHR

GluN1b-GluN2B NMDA receptor in non-active 2 conformation at 4 angstrom resolution
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者	Chou, T, Tajima, N, Furukawa, H.
登録日	2020-04-08
公開日	2020-08-05
実験手法	ELECTRON MICROSCOPY (3.99 Å)
主引用文献	Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020

6UZW

Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and UBP791
分子名称:	(2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
著者	Wang, J.X, Furukawa, H.
登録日	2019-11-15
公開日	2020-01-29
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.13 Å)
主引用文献	Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nat Commun, 11, 2020

6VD7

Cryo-EM structure of Xenopus tropicalis pannexin 1 channel
分子名称:	Pannexin
著者	Syrjanen, J.L, Michalski, M, Furukawa, H, Kawate, T.
登録日	2019-12-23
公開日	2020-02-26
最終更新日	2024-10-23
実験手法	ELECTRON MICROSCOPY (3.02 Å)
主引用文献	The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition. Elife, 9, 2020

6WHT

GluN1b-GluN2B NMDA receptor in active conformation at 4.4 angstrom resolution
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者	Chou, T, Tajima, N, Furukawa, H.
登録日	2020-04-08
公開日	2020-08-05
最終更新日	2024-10-23
実験手法	ELECTRON MICROSCOPY (4.39 Å)
主引用文献	Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020

6WI0

GluN1b-GluN2B NMDA receptor in complex with GluN1 antagonist L689,560, class 2
分子名称:	(2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Chou, T, Tajima, N, Furukawa, H.
登録日	2020-04-08
公開日	2020-07-15
最終更新日	2020-08-05
実験手法	ELECTRON MICROSCOPY (4.27 Å)
主引用文献	Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020

6WHX

GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 2
分子名称:	(2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ...
著者	Chou, T, Tajima, N, Furukawa, H.
登録日	2020-04-08
公開日	2020-07-15
最終更新日	2024-10-23
実験手法	ELECTRON MICROSCOPY (4.09 Å)
主引用文献	Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020

5FXJ

GluN1b-GluN2B NMDA receptor structure-Class X
分子名称:	GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1, NMDA 2B
著者	Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa H, H.
登録日	2016-03-02
公開日	2016-05-25
最終更新日	2024-05-08
実験手法	ELECTRON MICROSCOPY (6.25 Å)
主引用文献	Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016

5OJK

Crystal structure of the human neuroligin 1 cholinesterase domain containing spliced sequence B (SSB) (NL1(-A+B))
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-1,Neuroligin-1, TRIETHYLENE GLYCOL
著者	Elegheert, J, Aricescu, A.R.
登録日	2017-07-21
公開日	2017-08-23
最終更新日	2024-10-23
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron, 95, 2017

5OJ6

Crystal structure of the chicken MDGA1 ectodomain in complex with the human neuroligin 1 (NL1(-A-B)) cholinesterase domain.
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, MAM domain-containing glycosylphosphatidylinositol anchor protein 1, Neuroligin-1, ...
著者	Elegheert, J, Clayton, A.J, Aricescu, A.R.
登録日	2017-07-20
公開日	2017-08-23
最終更新日	2024-11-06
実験手法	X-RAY DIFFRACTION (3.3 Å)
主引用文献	Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron, 95, 2017

5OJ2

Crystal structure of the chicken MDGA1 ectodomain
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, MAM domain-containing glycosylphosphatidylinositol anchor protein 1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Elegheert, J, Clayton, A.J, Aricescu, A.R.
登録日	2017-07-20
公開日	2017-08-23
最終更新日	2024-11-06
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron, 95, 2017

4R0U

Tgvtava, an amyloid forming segment from alpha synuclein, residues 72-78
分子名称:	Alpha-synuclein
著者	Ivanova, M.I, Eisenberg, D.S, Sawaya, M.R.
登録日	2014-08-01
公開日	2014-12-17
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (1.38 Å)
主引用文献	Structure-based design of functional amyloid materials. J.Am.Chem.Soc., 136, 2014

4R0P

Ifqins, an amyloid forming segment from human lysozyme spanning residues 56-61
分子名称:	Lysozyme C
著者	Sievers, S, Eisenberg, D.S, Sawaya, M.R.
登録日	2014-08-01
公開日	2014-12-17
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.52 Å)
主引用文献	Structure-based design of functional amyloid materials. J.Am.Chem.Soc., 136, 2014

4R0W

Vvtgvta, an amyloid forming segment from alpha synuclein, residues 70-76
分子名称:	Alpha-synuclein
著者	Ivanova, M.I, Eisenberg, D.S, Sawaya, M.R.
登録日	2014-08-01
公開日	2014-12-17
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Structure-based design of functional amyloid materials. J.Am.Chem.Soc., 136, 2014

8IE2

Crystal structure of Lactiplantibacillus plantarum GlyRS
分子名称:	Glycine--tRNA ligase alpha subunit, Glycine--tRNA ligase beta subunit
著者	Yamashita, S, Tomita, K.
登録日	2023-02-15
公開日	2023-06-07
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (3.6 Å)
主引用文献	Mechanism of tRNA recognition by heterotetrameric glycyl-tRNA synthetase from lactic acid bacteria. J.Biochem., 174, 2023

4KFQ

Crystal structure of the NMDA receptor GluN1 ligand binding domain in complex with 1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one
分子名称:	1-sulfanyl[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one, GLYCEROL, Glutamate receptor ionotropic, ...
著者	Steffensen, T.B, Tabrizi, F.M, Gajhede, M, Kastrup, J.S.
登録日	2013-04-27
公開日	2013-10-09
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. J.Biol.Chem., 288, 2013

1Y1M

Crystal structure of the NR1 ligand binding core in complex with cycloleucine
分子名称:	1-AMINOCYCLOPENTANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit zeta 1
著者	Inanobe, A, Gouaux, E.
登録日	2004-11-18
公開日	2005-07-12
最終更新日	2024-10-09
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron, 47, 2005

1Y1Z

Crystal structure of the NR1 ligand binding core in complex with ACBC
分子名称:	1-AMINOCYCLOBUTANECARBOXLIC ACID, Glutamate [NMDA] receptor subunit zeta 1
著者	Inanobe, A, Gouaux, E.
登録日	2004-11-19
公開日	2005-07-12
最終更新日	2024-10-30
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron, 47, 2005

1Y20

Crystal structure of the NR1 ligand-binding core in complex with ACPC
分子名称:	1-AMINOCYCLOPROPANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit zeta 1
著者	Inanobe, A, Gouaux, E.
登録日	2004-11-19
公開日	2005-07-12
最終更新日	2017-07-26
実験手法	X-RAY DIFFRACTION (1.4 Å)
主引用文献	Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron, 47, 2005

<1 2 3 45

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