1HET
 
 | | atomic X-ray structure of liver alcohol dehydrogenase containing a hydroxide adduct to NADH | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, ALCOHOL DEHYDROGENASE E CHAIN, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Meijers, R, Morris, R.J, Adolph, H.W, Merli, A, Lamzin, V.S, Cedergen-Zeppezauer, E.S. | | 登録日 | 2000-11-25 | | 公開日 | 2001-05-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | On the Enzymatic Activation of Nadh
J.Biol.Chem., 276, 2001
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1P1R
 | | Horse liver alcohol dehydrogenase complexed with NADH and R-N-1-methylhexylformamide | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (R)-N-(1-METHYL-HEXYL)-FORMAMIDE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | | 著者 | Venkataramaiah, T.H, Plapp, B.V. | | 登録日 | 2003-04-13 | | 公開日 | 2003-07-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Formamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolism
J.Biol.Chem., 278, 2003
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1MG0
 | | Horse Liver Alcohol Dehydrogenase Complexed With NAD+ and 2,3-Difluorobenzyl Alcohol | | 分子名称: | 2,3-DIFLUOROBENZYL ALCOHOL, Alcohol Dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Rubach, J.K, Plapp, B.V. | | 登録日 | 2002-08-14 | | 公開日 | 2002-11-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mobility of Fluorobenzyl Alcohols Bound to Liver Alcohol Dehydrogenases as Determined by NMR and X-ray Crystallographic Studies
Biochemistry, 41, 2002
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1QV6
 | | HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,4-DIFLUOROBENZYL ALCOHOL | | 分子名称: | (2,4-DIFLUOROPHENYL)METHANOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Alcohol dehydrogenase E chain, ... | | 著者 | Lebrun, L.A, Park, D.-H, Ramaswamy, S, Plapp, B.V. | | 登録日 | 2003-08-26 | | 公開日 | 2004-01-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase.
Biochemistry, 43, 2004
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1QV7
 | | HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,3-DIFLUOROBENZYL ALCOHOL | | 分子名称: | 2,3-DIFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Lebrun, L.A, Park, D.-H, Ramaswamy, S, Plapp, B.V. | | 登録日 | 2003-08-27 | | 公開日 | 2004-01-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase.
Biochemistry, 43, 2004
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1MGO
 | | Horse Liver Alcohol Dehydrogenase Phe93Ala Mutant | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol Dehydrogenase E chain, ... | | 著者 | Rubach, J.K, Plapp, B.V. | | 登録日 | 2002-08-15 | | 公開日 | 2002-11-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Mobility of Fluorobenzyl Alcohols Bound to Liver Alcohol Dehydrogenases as Determined by NMR and X-ray Crystallographic Studies
Biochemistry, 41, 2002
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1BTO
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1JU9
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1QLH
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1QLJ
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1N8K
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1N92
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2BZN
 | | Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP | | 分子名称: | GMP REDUCTASE 2, INOSINIC ACID | | 著者 | Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Graslund, S, Hammarstrom, M, Hallberg, B.M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A, Weigelt, J. | | 登録日 | 2005-08-19 | | 公開日 | 2005-09-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
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2C6Q
 | | Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP and NADPH | | 分子名称: | GMP REDUCTASE 2, INOSINIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Kursula, P, Stenmark, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Graslund, S, Hammarstrom, M, Hallberg, B.M, Kotenyova, T, Nilsson-Ehle, P, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A, Weigelt, J, Nordlund, P. | | 登録日 | 2005-11-11 | | 公開日 | 2005-11-30 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
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4W6Z
 | | YEAST ALCOHOL DEHYDROGENASE I, SACCHAROMYCES CEREVISIAE FERMENTATIVE ENZYME | | 分子名称: | Alcohol dehydrogenase 1, NICOTINAMIDE-8-IODO-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... | | 著者 | plapp, B.v, savarimuthu, b.r, ramaswamy, s. | | 登録日 | 2014-08-21 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Yeast alcohol dehydrogenase structure and catalysis.
Biochemistry, 53, 2014
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2XAZ
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2XAW
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2XO5
 | | RIBONUCLEOTIDE REDUCTASE Y731NH2Y MODIFIED R1 SUBUNIT OF E. COLI | | 分子名称: | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA | | 著者 | Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J. | | 登録日 | 2010-08-09 | | 公開日 | 2010-08-18 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases.
J.Am.Chem.Soc., 133, 2011
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2XAX
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2XO4
 | | RIBONUCLEOTIDE REDUCTASE Y730NH2Y MODIFIED R1 SUBUNIT OF E. COLI | | 分子名称: | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA | | 著者 | Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J. | | 登録日 | 2010-08-09 | | 公開日 | 2010-08-18 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases.
J.Am.Chem.Soc., 133, 2011
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5ENV
 | | YEAST ALCOHOL DEHYDROGENASE WITH BOUND COENZYME | | 分子名称: | Alcohol dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... | | 著者 | Plapp, B.V, Charlier Jr, H.A, Ramaswamy, S. | | 登録日 | 2015-11-09 | | 公開日 | 2015-11-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Mechanistic implications from structures of yeast alcohol dehydrogenase complexed with coenzyme and an alcohol.
Arch.Biochem.Biophys., 591, 2015
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4DWV
 | | Horse alcohol dehydrogenase complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ... | | 著者 | Plapp, B.V, Ramaswamy, S. | | 登録日 | 2012-02-26 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Atomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD(+) and Fluoroalcohols Define Strained Michaelis Complexes.
Biochemistry, 51, 2012
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2PUO
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2PVD
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2PVG
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