1P1R
Horse liver alcohol dehydrogenase complexed with NADH and R-N-1-methylhexylformamide
Summary for 1P1R
Entry DOI | 10.2210/pdb1p1r/pdb |
Related | 1HLD 1LDE 1LDY 1N8K 1N92 3BTO |
Descriptor | Alcohol dehydrogenase E chain, ZINC ION, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... (6 entities in total) |
Functional Keywords | puckered reduced nicotinamide ring, michaelis complex analogue, formamide, oxidoreductase |
Biological source | Equus caballus (horse) |
Cellular location | Cytoplasm: P00327 |
Total number of polymer chains | 4 |
Total formula weight | 163289.21 |
Authors | Venkataramaiah, T.H.,Plapp, B.V. (deposition date: 2003-04-13, release date: 2003-07-15, Last modification date: 2023-08-16) |
Primary citation | Venkataramaiah, T.H.,Plapp, B.V. Formamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolism J.Biol.Chem., 278:36699-36706, 2003 Cited by PubMed: 12855684DOI: 10.1074/jbc.M305419200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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