Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1P1R

Horse liver alcohol dehydrogenase complexed with NADH and R-N-1-methylhexylformamide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
A	0004745	molecular_function	all-trans-retinol dehydrogenase (NAD+) activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0042572	biological_process	retinol metabolic process
A	0042573	biological_process	retinoic acid metabolic process
A	0046872	molecular_function	metal ion binding
B	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
B	0004745	molecular_function	all-trans-retinol dehydrogenase (NAD+) activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008270	molecular_function	zinc ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0042572	biological_process	retinol metabolic process
B	0042573	biological_process	retinoic acid metabolic process
B	0046872	molecular_function	metal ion binding
C	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
C	0004745	molecular_function	all-trans-retinol dehydrogenase (NAD+) activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008270	molecular_function	zinc ion binding
C	0016491	molecular_function	oxidoreductase activity
C	0042572	biological_process	retinol metabolic process
C	0042573	biological_process	retinoic acid metabolic process
C	0046872	molecular_function	metal ion binding
D	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
D	0004745	molecular_function	all-trans-retinol dehydrogenase (NAD+) activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008270	molecular_function	zinc ion binding
D	0016491	molecular_function	oxidoreductase activity
D	0042572	biological_process	retinol metabolic process
D	0042573	biological_process	retinoic acid metabolic process
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 375

Chain	Residue
A	CYS46
A	HIS67
A	CYS174
A	NAI377
A	NMH378

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 376

Chain	Residue
A	CYS97
A	CYS100
A	CYS103
A	CYS111

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 375

Chain	Residue
B	CYS46
B	HIS67
B	CYS174
B	NAI377
B	NMH378

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 376

Chain	Residue
B	CYS97
B	CYS100
B	CYS103
B	CYS111

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C 375

Chain	Residue
C	CYS46
C	HIS67
C	CYS174
C	NAI377
C	NMH378

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 376

Chain	Residue
C	CYS97
C	CYS100
C	CYS103
C	CYS111

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 375

Chain	Residue
D	CYS46
D	HIS67
D	CYS174
D	NAI377
D	NMH378

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 376

Chain	Residue
D	CYS97
D	CYS100
D	CYS103
D	CYS111

site_id	AC9
Number of Residues	29
Details	BINDING SITE FOR RESIDUE NAI A 377

Chain	Residue
A	ARG47
A	SER48
A	HIS51
A	CYS174
A	THR178
A	GLY199
A	GLY201
A	GLY202
A	VAL203
A	ASP223
A	ILE224
A	VAL268
A	ILE269
A	ARG271
A	VAL292
A	GLY293
A	VAL294
A	ALA317
A	ILE318
A	PHE319
A	ARG369
A	ZN375
A	NMH378
A	HOH7025
A	HOH7045
A	HOH7046
A	HOH7155
A	HOH7218
A	HOH8024

site_id	BC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE NMH A 378

Chain	Residue
A	CYS46
A	SER48
A	LEU57
A	HIS67
A	PHE93
A	LEU116
A	CYS174
A	VAL294
A	ILE318
A	ZN375
A	NAI377
B	LEU309

site_id	BC2
Number of Residues	30
Details	BINDING SITE FOR RESIDUE NAI B 377

Chain	Residue
B	NMH378
B	HOH7727
B	HOH7747
B	HOH7748
B	HOH7875
B	HOH7891
B	HOH7915
B	HOH7923
B	ARG47
B	SER48
B	HIS51
B	CYS174
B	THR178
B	GLY199
B	GLY201
B	GLY202
B	VAL203
B	ASP223
B	ILE224
B	VAL268
B	ILE269
B	ARG271
B	VAL292
B	GLY293
B	VAL294
B	ALA317
B	ILE318
B	PHE319
B	ARG369
B	ZN375

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE NMH B 378

Chain	Residue
A	LEU309
B	CYS46
B	SER48
B	HIS67
B	PHE93
B	LEU116
B	CYS174
B	VAL294
B	ILE318
B	ZN375
B	NAI377

site_id	BC4
Number of Residues	30
Details	BINDING SITE FOR RESIDUE NAI C 377

Chain	Residue
C	ARG47
C	SER48
C	HIS51
C	CYS174
C	THR178
C	GLY199
C	GLY201
C	GLY202
C	VAL203
C	ASP223
C	ILE224
C	VAL268
C	ILE269
C	ARG271
C	VAL292
C	GLY293
C	VAL294
C	ALA317
C	ILE318
C	PHE319
C	ARG369
C	ZN375
C	NMH378
C	HOH7256
C	HOH7260
C	HOH7277
C	HOH7278
C	HOH7391
C	HOH7462
C	HOH8104

site_id	BC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE NMH C 378

Chain	Residue
C	CYS46
C	SER48
C	HIS67
C	PHE93
C	LEU116
C	CYS174
C	VAL294
C	ILE318
C	ZN375
C	NAI377
D	LEU309

site_id	BC6
Number of Residues	32
Details	BINDING SITE FOR RESIDUE NAI D 377

Chain	Residue
D	ARG47
D	SER48
D	HIS51
D	CYS174
D	THR178
D	GLY199
D	GLY201
D	GLY202
D	VAL203
D	ASP223
D	ILE224
D	LYS228
D	VAL268
D	ILE269
D	ARG271
D	VAL292
D	GLY293
D	VAL294
D	ALA317
D	ILE318
D	PHE319
D	ARG369
D	ZN375
D	NMH378
D	HOH7501
D	HOH7521
D	HOH7522
D	HOH7645
D	HOH7660
D	HOH7664
D	HOH7683
D	HOH7687

site_id	BC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE NMH D 378

Chain	Residue
C	MET306
C	LEU309
D	CYS46
D	SER48
D	HIS67
D	PHE93
D	LEU116
D	CYS174
D	VAL294
D	ZN375
D	NAI377

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MPD B 2001

Chain	Residue
B	ARG218
B	GLU239
C	ARG218
C	THR238
C	GLU239

Functional Information from PROSITE/UniProt

site_id	PS00059
Number of Residues	15
Details	ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEaAGIvesiGegV

Chain	Residue	Details
A	GLY66-VAL80

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"178875","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P06525","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"178875","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	4
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"5466062","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
A	LEU57

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
B	LEU57

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
C	LEU57

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
D	LEU57

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
A	SER48
A	HIS51

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
B	SER48
B	HIS51

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
C	SER48
C	HIS51

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
D	SER48
D	HIS51

site_id	MCSA1
Number of Residues	5
Details	M-CSA 256

Chain	Residue	Details
A	CYS46	metal ligand
A	SER48	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
A	HIS51	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
A	HIS67	metal ligand
A	CYS174	metal ligand

site_id	MCSA2
Number of Residues	5
Details	M-CSA 256

Chain	Residue	Details
B	CYS46	metal ligand
B	SER48	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
B	HIS51	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
B	HIS67	metal ligand
B	CYS174	metal ligand

site_id	MCSA3
Number of Residues	5
Details	M-CSA 256

Chain	Residue	Details
C	CYS46	metal ligand
C	SER48	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
C	HIS51	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
C	HIS67	metal ligand
C	CYS174	metal ligand

site_id	MCSA4
Number of Residues	5
Details	M-CSA 256

Chain	Residue	Details
D	CYS46	metal ligand
D	SER48	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
D	HIS51	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
D	HIS67	metal ligand
D	CYS174	metal ligand

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)