1QV6

HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,4-DIFLUOROBENZYL ALCOHOL

Summary for 1QV6

• Entry DOI: 10.2210/pdb1qv6/pdb
• Related: 1HLD 1MG0 1QV7
• Descriptor: Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (6 entities in total)
• Functional Keywords: dehydrogenase, alcohol, nicotinamide coenzyme, 2, 4-difluorobenzyl alcohol, his51gln/lys228arg mutant, horse liver, oxidoreductase
• Biological source: Equus caballus (horse)
• Cellular location: Cytoplasm: P00327
• Total number of polymer chains: 2
• Total formula weight: 81737.44

Authors

Lebrun, L.A.,Park, D.-H.,Ramaswamy, S.,Plapp, B.V. (deposition date: 2003-08-26, release date: 2004-01-20, Last modification date: 2023-08-16)

• Primary citation: LeBrun, L.A.,Park, D.-H.,Ramaswamy, S.,Plapp, B.V.; Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase.; Biochemistry, 43:3014-3026, 2004; PubMed: 15023053; DOI: 10.1021/bi036103m

Experimental method

X-RAY DIFFRACTION (1.8 Å)