1QV6
HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,4-DIFLUOROBENZYL ALCOHOL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alcohol dehydrogenase E chain | polymer | 374 | 39871.3 | 2 | UniProt (P00327) Pfam (PF08240) Pfam (PF00107) | Equus caballus (horse) | |
| 2 | C, D, H, I (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, J (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 4 | F, K (A, B) | (2,4-DIFLUOROPHENYL)METHANOL | non-polymer | 144.1 | 2 | Chemie (24B) | |||
| 5 | G (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 579 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 374 (UniProt: P00327)
| PDB | External Database | Details |
|---|---|---|
| Gln 51 | His 51 | engineered mutation |
| Arg 228 | Lys 228 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79742.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1994.9 | |
| All* | Total formula weight | 81737.4 |
