1QV7

HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,3-DIFLUOROBENZYL ALCOHOL

Summary for 1QV7

Entry DOI	10.2210/pdb1qv7/pdb
Related	1HLD 1MG0 1QV6
Descriptor	Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	dehydrogenase, alcohol, nicotinamide coenzyme, 2, 3-difluorobenzyl alcohol, his51gln/lys228arg mutant, horse liver, oxidoreductase
Biological source	Equus caballus (horse)
Cellular location	Cytoplasm: P00327
Total number of polymer chains	2
Total formula weight	81619.26
Authors	Lebrun, L.A.,Park, D.-H.,Ramaswamy, S.,Plapp, B.V. (deposition date: 2003-08-27, release date: 2004-01-20, Last modification date: 2023-08-16)
Primary citation	LeBrun, L.A.,Park, D.-H.,Ramaswamy, S.,Plapp, B.V. Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase. Biochemistry, 43:3014-3026, 2004 Cited by PubMed: 15023053 DOI: 10.1021/bi036103m PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation