Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1QV7

HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,3-DIFLUOROBENZYL ALCOHOL

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
A	0004745	molecular_function	all-trans-retinol dehydrogenase (NAD+) activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0042572	biological_process	retinol metabolic process
A	0042573	biological_process	retinoic acid metabolic process
A	0046872	molecular_function	metal ion binding
B	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
B	0004745	molecular_function	all-trans-retinol dehydrogenase (NAD+) activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008270	molecular_function	zinc ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0042572	biological_process	retinol metabolic process
B	0042573	biological_process	retinoic acid metabolic process
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 375

Chain	Residue
A	CYS46
A	HIS67
A	CYS174
A	NAD377
A	DFB378

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 376

Chain	Residue
A	CYS97
A	CYS100
A	CYS103
A	CYS111

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 375

Chain	Residue
B	CYS46
B	HIS67
B	CYS174
B	NAD377
B	DFB378

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 376

Chain	Residue
B	CYS97
B	CYS100
B	CYS103
B	CYS111

site_id	AC5
Number of Residues	27
Details	BINDING SITE FOR RESIDUE NAD A 377

Chain	Residue
A	ARG47
A	SER48
A	GLN51
A	CYS174
A	THR178
A	GLY199
A	GLY201
A	GLY202
A	VAL203
A	ASP223
A	ILE224
A	ARG228
A	VAL268
A	ILE269
A	VAL292
A	GLY293
A	VAL294
A	ALA317
A	ILE318
A	PHE319
A	ARG369
A	ZN375
A	DFB378
A	HOH381
A	HOH424
A	HOH453
A	HOH539

site_id	AC6
Number of Residues	28
Details	BINDING SITE FOR RESIDUE NAD B 377

Chain	Residue
B	ARG47
B	SER48
B	GLN51
B	CYS174
B	THR178
B	GLY199
B	GLY201
B	GLY202
B	VAL203
B	ASP223
B	ILE224
B	ASN225
B	ARG228
B	VAL268
B	ILE269
B	VAL292
B	GLY293
B	VAL294
B	ALA317
B	ILE318
B	PHE319
B	ARG369
B	ZN375
B	DFB378
B	HOH386
B	HOH471
B	HOH501
B	HOH525

site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE DFB A 378

Chain	Residue
A	CYS46
A	SER48
A	LEU57
A	HIS67
A	PHE93
A	LEU141
A	CYS174
A	VAL294
A	ZN375
A	NAD377

site_id	AC8
Number of Residues	11
Details	BINDING SITE FOR RESIDUE DFB B 378

Chain	Residue
B	CYS46
B	SER48
B	LEU57
B	HIS67
B	PHE93
B	LEU116
B	CYS174
B	VAL294
B	ILE318
B	ZN375
B	NAD377

Functional Information from PROSITE/UniProt

site_id	PS00059
Number of Residues	15
Details	ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEaAGIvesiGegV

Chain	Residue	Details
A	GLY66-VAL80

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"178875","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P06525","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"178875","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"5466062","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
A	LEU57

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
B	LEU57

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
A	SER48
A	GLN51

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
B	SER48
B	GLN51

site_id	MCSA1
Number of Residues	5
Details	M-CSA 256

Chain	Residue	Details
A	CYS46	metal ligand
A	SER48	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
A	GLN51	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
A	HIS67	metal ligand
A	CYS174	metal ligand

site_id	MCSA2
Number of Residues	5
Details	M-CSA 256

Chain	Residue	Details
B	CYS46	metal ligand
B	SER48	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
B	GLN51	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
B	HIS67	metal ligand
B	CYS174	metal ligand

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)