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Crystal Structure of Broadly Neutralizing VRC01-class Antibody N6 in Complex with HIV-1 Clade AE Strain 93TH057 gp120 Core
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Heavy chain of N6, ...
著者	Zhou, T, Kwong, P.D.
登録日	2016-09-20
公開日	2016-11-16
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. Immunity, 45, 2016

5TKK

Structure of mouse vaccination-elicited HIV neutralizing antibody vFP5.01 in complex with HIV-1 fusion peptide residue 512-519
分子名称:	HIV-1 fusion peptide residue 512-519, mouse antibody vFP5.01 heavy chain, mouse antibody vFP5.01 light chain
著者	Xu, K, Liu, K, Kwong, P.D.
登録日	2016-10-06
公開日	2018-04-04
最終更新日	2018-06-27
実験手法	X-RAY DIFFRACTION (1.55 Å)
主引用文献	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nat. Med., 24, 2018

5TE7

Crystal Structure of Broadly Neutralizing VRC01-class Antibody N6 in Complex with HIV-1 Clade C Strain DU172.17 gp120 Core
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者	Zhou, T, Kwong, P.D.
登録日	2016-09-20
公開日	2016-11-16
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.15 Å)
主引用文献	Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. Immunity, 45, 2016

7LL2

Cryo-EM structure of BG505 DS-SOSIP in complex with Glycan276-Dependent Broadly Neutralizing Antibody VRC33.01 Fab
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者	Manne, K, Acharya, P.
登録日	2021-02-03
公開日	2021-03-17
最終更新日	2021-11-17
実験手法	ELECTRON MICROSCOPY (3.73 Å)
主引用文献	Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies. Cell Rep, 37, 2021

7LL1

Cryo-EM structure of BG505 DS-SOSIP in complex with glycan276-dependent broadly neutralizing antibody VRC40.01 Fab
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Envelope glycoprotein gp41, ...
著者	Manne, K, Acharya, P.
登録日	2021-02-03
公開日	2021-03-17
最終更新日	2021-11-17
実験手法	ELECTRON MICROSCOPY (3.73 Å)
主引用文献	Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies. Cell Rep, 37, 2021

7LUC

Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B
分子名称:	01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ...
著者	Wrapp, D, McLellan, J.S.
登録日	2021-02-22
公開日	2021-04-21
最終更新日	2021-04-28
実験手法	ELECTRON MICROSCOPY (3.21 Å)
主引用文献	Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021

7LRT

Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 spike glycoprotein, ...
著者	Zhou, T, Tsybovsky, T.
登録日	2021-02-17
公開日	2021-07-14
最終更新日	2021-08-25
実験手法	ELECTRON MICROSCOPY (3.54 Å)
主引用文献	Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021

7LRS

Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain
分子名称:	Spike glycoprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, antibody A23-58.1 heavy chain, ...
著者	Zhou, T, Tsybovsky, Y.
登録日	2021-02-17
公開日	2021-07-14
最終更新日	2021-08-25
実験手法	ELECTRON MICROSCOPY (3.89 Å)
主引用文献	Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021

7LY9

Cryo-EM structure of 2909 Fab in complex with 3BNC117 Fab and CAP256.wk34.c80 SOSIP.RnS2 N160K HIV-1 Env trimer
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2909 Heavy Chain, ...
著者	Gorman, J, Kwong, P.D.
登録日	2021-03-06
公開日	2021-08-18
最終更新日	2021-11-24
実験手法	ELECTRON MICROSCOPY (3.91 Å)
主引用文献	Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces. Nat Commun, 12, 2021

7LPN

Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者	Gorman, J, Kwong, P.D.
登録日	2021-02-12
公開日	2022-02-23
最終更新日	2023-03-29
実験手法	ELECTRON MICROSCOPY (3.61 Å)
主引用文献	Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022

7MLZ

Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain
分子名称:	B1-182.1 Fab heavy chain, B1-182.1 Fab light chain, Spike protein S1, ...
著者	Zhou, T, Tsybovsky, T, Kwong, P.D.
登録日	2021-04-29
公開日	2021-07-28
最終更新日	2021-08-25
実験手法	ELECTRON MICROSCOPY (3.71 Å)
主引用文献	Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021

7MM0

Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B1-182.1 Fab heavy chain, ...
著者	Zhou, T, Tsybovsky, T, Kwong, P.D.
登録日	2021-04-29
公開日	2021-07-28
最終更新日	2021-08-25
実験手法	ELECTRON MICROSCOPY (3.15 Å)
主引用文献	Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021

7MXD

Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J038 in complex with HIV-1 Env
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody heavy chain, ...
著者	Zhou, T, Gao, F.
登録日	2021-05-19
公開日	2022-03-30
最終更新日	2022-06-22
実験手法	ELECTRON MICROSCOPY (3.4 Å)
主引用文献	Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2. Adv Sci, 9, 2022

7N28

Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J033 in complex with HIV-1 Env
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody heavy chain, ...
著者	Zhou, T, Gao, F.
登録日	2021-05-28
公開日	2022-04-06
最終更新日	2022-06-22
実験手法	ELECTRON MICROSCOPY (4.2 Å)
主引用文献	Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2. Adv Sci, 9, 2022

7LG6

BG505 SOSIP.v5.2 in complex with VRC40.01 and RM19R Fabs
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者	Cottrell, C.A, Torres, J.L, Wu, N.R, Ward, A.B.
登録日	2021-01-19
公開日	2021-09-15
最終更新日	2021-11-17
実験手法	ELECTRON MICROSCOPY (3.28 Å)
主引用文献	Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies. Cell Rep, 37, 2021

7LLK

Cryo-EM structure of Q23.17_DS-SOSIP in complex with Glycan276-Dependent Broadly Neutralizing Antibody 179NC75 Fab
分子名称:	179NC75 Fab Heavy chain, 179NC75 Fab Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Manne, K, Acharya, P.
登録日	2021-02-04
公開日	2021-06-02
最終更新日	2021-11-17
実験手法	ELECTRON MICROSCOPY (4.8 Å)
主引用文献	Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies. Cell Rep, 37, 2021

7LUE

Prefusion RSV F glycoprotein bound by neutralizing site V-directed antibody ADI-14442
分子名称:	Fusion glycoprotein F0, Heavy chain of human antibody Fab ADI-14442, Light chain of human antibody Fab ADI-14442
著者	Gilman, M.S.A, McLellan, J.S.
登録日	2021-02-22
公開日	2021-06-16
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021

7LUD

Crystal structure of Fab ADI-14442
分子名称:	ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION
著者	Rush, S.A, McLellan, J.S.
登録日	2021-02-22
公開日	2021-06-16
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021

4OLU

Crystal structure of antibody VRC07 in complex with clade A/E 93TH057 HIV-1 gp120 core
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ...
著者	Kwon, Y.D, Kwong, P.D.
登録日	2014-01-25
公開日	2014-09-03
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.202 Å)
主引用文献	Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014

4OLV

Crystal structure of antibody VRC07-G54F in complex with clade A/E 93TH057 HIV-1 gp120 core
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ...
著者	Kwon, Y.D, Kwong, P.D.
登録日	2014-01-25
公開日	2014-09-03
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014

4OLY

Crystal structure of antibody VRC07-G54R in complex with clade A/E 93TH057 HIV-1 gp120 core
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ...
著者	Kwon, Y.D, Kwong, P.D.
登録日	2014-01-25
公開日	2014-09-03
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.351 Å)
主引用文献	Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014

4OM0

Crystal structure of antibody VRC07-G54Y in complex with clade A/E 93TH057 HIV-1 gp120 core
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ...
著者	Kwon, Y.D, Kwong, P.D.
登録日	2014-01-25
公開日	2014-09-03
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.289 Å)
主引用文献	Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014

4OLW

Crystal structure of antibody VRC07-G54H in complex with clade A/E 93TH057 HIV-1 gp120 core
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ...
著者	Kwon, Y.D, Kwong, P.D.
登録日	2014-01-25
公開日	2014-09-03
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.709 Å)
主引用文献	Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014

4OM1

Crystal structure of antibody VRC07-I30Q, G54W, S58N in complex with clade A/E 93TH057 HIV-1 gp120 core
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ...
著者	Kwon, Y.D, Kwong, P.D.
登録日	2014-01-25
公開日	2014-09-03
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.131 Å)
主引用文献	Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014

4OLZ

Crystal structure of antibody VRC07-G54W in complex with clade A/E 93TH057 HIV-1 gp120 core
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ...
著者	Kwon, Y.D, Kwong, P.D.
登録日	2014-01-25
公開日	2014-09-03
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014

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