3RTT
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![BU of 3rtt by Molmil](/molmil-images/mine/3rtt) | Human MMP-12 catalytic domain in complex with*(R)-N*-Hydroxy-1-(phenethylsulfonyl)pyrrolidine-2-carboxamide | 分子名称: | CALCIUM ION, Macrophage metalloelastase, N-hydroxy-1-[(2-phenylethyl)sulfonyl]-D-prolinamide, ... | 著者 | Bertini, I, Calderone, V, Fragai, M, Luchinat, C, Mori, M, Nativi, C. | 登録日 | 2011-05-04 | 公開日 | 2012-07-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Contribution of ligand free energy of solvation to design new potent MMPs inhibitors. J.Med.Chem., 2012
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3RTS
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![BU of 3rts by Molmil](/molmil-images/mine/3rts) | Human MMP-12 catalytic domain in complex with*N*-Hydroxy-2-(2-phenylethylsulfonamido)acetamide | 分子名称: | CALCIUM ION, Macrophage metalloelastase, N-hydroxy-N~2~-[(2-phenylethyl)sulfonyl]glycinamide, ... | 著者 | Bertini, I, Calderone, V, Fragai, M, Luchinat, C, Mori, M, Nativi, C. | 登録日 | 2011-05-04 | 公開日 | 2012-07-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Contribution of ligand free energy of solvation to design new potent MMPs inhibitors. J.Med.Chem., 2012
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3H66
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![BU of 3h66 by Molmil](/molmil-images/mine/3h66) | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Zn2+ atoms | 分子名称: | Serine/threonine-protein phosphatase 5, ZINC ION | 著者 | Bertini, I, Calderone, V, Fragai, M, Luchinat, C, Talluri, E. | 登録日 | 2009-04-23 | 公開日 | 2009-09-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin J.Med.Chem., 52, 2009
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1BQX
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![BU of 1bqx by Molmil](/molmil-images/mine/1bqx) | ARTIFICIAL FE8S8 FERREDOXIN: THE D13C VARIANT OF BACILLUS SCHLEGELII FE7S8 FERREDOXIN | 分子名称: | IRON/SULFUR CLUSTER, PROTEIN (FERREDOXIN) | 著者 | Aono, S, Bentrop, D, Bertini, I, Cosenza, G, Luchinat, C. | 登録日 | 1998-08-20 | 公開日 | 1998-08-26 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of an artificial Fe8S8 ferredoxin: the D13C variant of Bacillus schlegelii Fe7S8 ferredoxin. Eur.J.Biochem., 258, 1998
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1BC6
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![BU of 1bc6 by Molmil](/molmil-images/mine/1bc6) | 7-FE FERREDOXIN FROM BACILLUS SCHLEGELII, NMR, 20 STRUCTURES | 分子名称: | 7-FE FERREDOXIN, FE3-S4 CLUSTER, IRON/SULFUR CLUSTER | 著者 | Aono, S, Bentrop, D, Bertini, I, Donaire, A, Luchinat, C, Niikura, Y, Rosato, A. | 登録日 | 1998-05-05 | 公開日 | 1998-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the oxidized Fe7S8 ferredoxin from the thermophilic bacterium Bacillus schlegelii by 1H NMR spectroscopy. Biochemistry, 37, 1998
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2KTM
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![BU of 2ktm by Molmil](/molmil-images/mine/2ktm) | Solution NMR structure of H2H3 domain of ovine prion protein (residues 167-234) | 分子名称: | Major prion protein | 著者 | Pastore, A, Adrover, M, Pauwels, K, de Chiara, C, Prigent, S, Rezeai, H. | 登録日 | 2010-02-04 | 公開日 | 2010-04-07 | 最終更新日 | 2021-11-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Prion fibrillization is mediated by a native structural element that comprises helices H2 and H3. J.Biol.Chem., 285, 2010
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6GE9
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![BU of 6ge9 by Molmil](/molmil-images/mine/6ge9) | Structure of Mycobacterium tuberculosis GlmU bound to Glc-1P and Ac-CoA | 分子名称: | 1,2-ETHANEDIOL, 1-O-phosphono-alpha-D-glucopyranose, ACETYL COENZYME *A, ... | 著者 | Craggs, P.D, Mouilleron, S, Rejzek, M, de Chiara, C, Young, R.J, Field, R.A, Argyrou, A, de Carvalho, L.P.S. | 登録日 | 2018-04-25 | 公開日 | 2018-05-02 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU. Biochemistry, 57, 2018
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3BA0
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![BU of 3ba0 by Molmil](/molmil-images/mine/3ba0) | Crystal structure of full-length human MMP-12 | 分子名称: | ACETOHYDROXAMIC ACID, CALCIUM ION, Macrophage metalloelastase, ... | 著者 | Bertini, I, Calderone, V, Fragai, M, Jaiswal, R, Luchinat, C, Melikian, M, Myonas, E, Svergun, D.I. | 登録日 | 2007-11-07 | 公開日 | 2008-07-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12. J.Am.Chem.Soc., 130, 2008
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1OA2
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![BU of 1oa2 by Molmil](/molmil-images/mine/1oa2) | Comparison of Family 12 Glycoside Hydrolases and Recruited Substitutions Important for Thermal Stability | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-BETA-1,4-GLUCANASE | 著者 | Sandgren, M, Gualfetti, P.J, Shaw, A, Gross, L.S, Saldajeno, M, Day, A.G, Jones, T.A, Mitchinson, C. | 登録日 | 2002-12-28 | 公開日 | 2003-03-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Comparison of Family 12 Glycoside Hydrolases and Recruited Substitutions Important for Thermal Stability Protein Sci., 12, 2003
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2VTC
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![BU of 2vtc by Molmil](/molmil-images/mine/2vtc) | The structure of a glycoside hydrolase family 61 member, Cel61B from the Hypocrea jecorina. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CEL61B, NICKEL (II) ION | 著者 | Karkehabadi, S, Hansson, H, Kim, S, Piens, K, Mitchinson, C, Sandgren, M. | 登録日 | 2008-05-14 | 公開日 | 2008-09-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The First Structure of a Glycoside Hydrolase Family 61 Member, Cel61B from the Hypocrea Jecorina, at 1.6 A Resolution. J.Mol.Biol., 383, 2008
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6EOK
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![BU of 6eok by Molmil](/molmil-images/mine/6eok) | Crystal structure of E. coli L-asparaginase II | 分子名称: | L-asparaginase 2, ZINC ION | 著者 | Cerofolini, L, Giuntini, S, Carlon, A, Ravera, E, Calderone, V, Fragai, M, Parigi, G, Luchinat, C. | 登録日 | 2017-10-09 | 公開日 | 2018-10-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Characterization of PEGylated Asparaginase: New Opportunities from NMR Analysis of Large PEGylated Therapeutics. Chemistry, 25, 2019
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1OA4
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![BU of 1oa4 by Molmil](/molmil-images/mine/1oa4) | Comparison of Family 12 Glycoside Hydrolases and Recruited Substitutions Important for Thermal Stability | 分子名称: | ENDO-BETA-1,4-GLUCANASE | 著者 | Sandgren, M, Gualfetti, P.J, Shaw, A, Gross, L.S, Saldajeno, M, Day, A.G, Jones, T.A, Mitchinson, C. | 登録日 | 2002-12-28 | 公開日 | 2003-03-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Comparison of Family 12 Glycoside Hydrolases and Recruited Substitutions Important for Thermal Stability Protein Sci., 12, 2003
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1OS2
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![BU of 1os2 by Molmil](/molmil-images/mine/1os2) | Ternary enzyme-product-inhibitor complexes of human MMP12 | 分子名称: | ACETATE ION, ACETOHYDROXAMIC ACID, AZIDE ION, ... | 著者 | Bertini, I, Calderone, V, Fragai, M, Luchinat, C, Mangani, S, Terni, B. | 登録日 | 2003-03-18 | 公開日 | 2003-08-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | X-ray Structures of Binary and Ternary Enzyme-Product-Inhibitor Complexes of Matrix Metalloproteinases Angew.Chem.Int.Ed.Engl., 42, 2003
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1OT4
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![BU of 1ot4 by Molmil](/molmil-images/mine/1ot4) | Solution structure of Cu(II)-CopC from Pseudomonas syringae | 分子名称: | COPPER (II) ION, Copper resistance protein C | 著者 | Arnesano, F, Banci, L, Bertini, I, Felli, I.C, Luchinat, C, Thompsett, A.R, Structural Proteomics in Europe (SPINE) | 登録日 | 2003-03-21 | 公開日 | 2003-07-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A Strategy for the NMR Characterization of Type II Copper(II) Proteins:
the Case of the Copper Trafficking Protein CopC from Pseudomonas Syringae. J.Am.Chem.Soc., 125, 2003
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6H6S
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![BU of 6h6s by Molmil](/molmil-images/mine/6h6s) | Sad phasing on nickel-substituted human carbonic anhydrase II | 分子名称: | Carbonic anhydrase 2, NICKEL (II) ION | 著者 | Calderone, V, Fragai, M, Silva, J.P, Luchinat, C, Ravera, E, Geraldes, C.F.G.C, Macedo, A.L, Cerofolini, L, Giuntini, S. | 登録日 | 2018-07-30 | 公開日 | 2019-01-09 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Non-crystallographic symmetry in proteins: Jahn-Teller-like and Butterfly-like effects? J. Biol. Inorg. Chem., 24, 2019
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1OA3
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![BU of 1oa3 by Molmil](/molmil-images/mine/1oa3) | Comparison of Family 12 Glycoside Hydrolases and Recruited Substitutions Important for Thermal Stability | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-BETA-1-4-GLUCANASE | 著者 | Sandgren, M, Gualfetti, P.J, Shaw, A, Gross, L.S, Saldajeno, M, Day, A.G, Jones, T.A, Mitchinson, C. | 登録日 | 2002-12-28 | 公開日 | 2003-03-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Comparison of Family 12 Glycoside Hydrolases and Recruited Substitutions Important for Thermal Stability Protein Sci., 12, 2003
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2M41
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![BU of 2m41 by Molmil](/molmil-images/mine/2m41) | |
1Y93
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![BU of 1y93 by Molmil](/molmil-images/mine/1y93) | Crystal structure of the catalytic domain of human MMP12 complexed with acetohydroxamic acid at atomic resolution | 分子名称: | ACETOHYDROXAMIC ACID, CALCIUM ION, Macrophage metalloelastase, ... | 著者 | Bertini, I, Calderone, V, Cosenza, M, Fragai, M, Lee, Y.-M, Luchinat, C, Mangani, S, Terni, B, Turano, P. | 登録日 | 2004-12-14 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | Conformational variability of matrix metalloproteinases: Beyond a single 3D structure Proc.Natl.Acad.Sci.Usa, 102, 2005
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1OS9
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![BU of 1os9 by Molmil](/molmil-images/mine/1os9) | Binary enzyme-product complexes of human MMP12 | 分子名称: | CALCIUM ION, Macrophage metalloelastase, ZINC ION | 著者 | Bertini, I, Calderone, V, Fragai, M, Luchinat, C, Mangani, S, Terni, B. | 登録日 | 2003-03-19 | 公開日 | 2003-08-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | X-ray Structures of Binary and Ternary Enzyme-Product-Inhibitor Complexes of Matrix Metalloproteinases Angew.Chem.Int.Ed.Engl., 42, 2003
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2OXZ
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![BU of 2oxz by Molmil](/molmil-images/mine/2oxz) | Human MMP-12 in complex with two peptides PQG and IAG | 分子名称: | CALCIUM ION, ILE-ALA-GLY peptide, Macrophage metalloelastase, ... | 著者 | Calderone, V, Bertini, I, Fragai, M, Luchinat, C, Maletta, M, Yeo, K.J. | 登録日 | 2007-02-21 | 公開日 | 2007-03-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Snapshots of the reaction mechanism of matrix metalloproteinases. ANGEW.CHEM.INT.ED.ENGL., 45, 2006
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1FMY
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![BU of 1fmy by Molmil](/molmil-images/mine/1fmy) | HIGH RESOLUTION SOLUTION STRUCTURE OF THE PROTEIN PART OF CU7 METALLOTHIONEIN | 分子名称: | METALLOTHIONEIN | 著者 | Bertini, I, Hartmann, H.J, Klein, T, Liu, G, Luchinat, C, Weser, U. | 登録日 | 2000-08-18 | 公開日 | 2000-09-13 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | High resolution solution structure of the protein part of Cu7 metallothionein. Eur.J.Biochem., 267, 2000
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2OXW
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![BU of 2oxw by Molmil](/molmil-images/mine/2oxw) | Human MMP-12 complexed with the peptide IAG | 分子名称: | CALCIUM ION, ILE-ALA-GLY peptide, Macrophage metalloelastase, ... | 著者 | Calderone, V, Bertini, I, Fragai, M, Luchinat, C, Maletta, M, Yeo, K.J. | 登録日 | 2007-02-21 | 公開日 | 2007-03-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Snapshots of the reaction mechanism of matrix metalloproteinases. ANGEW.CHEM.INT.ED.ENGL., 45, 2006
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2OXU
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![BU of 2oxu by Molmil](/molmil-images/mine/2oxu) | Uninhibited form of human MMP-12 | 分子名称: | CALCIUM ION, Macrophage metalloelastase, ZINC ION | 著者 | Calderone, V, Bertini, I, Fragai, M, Luchinat, C, Maletta, M, Yeo, K.J. | 登録日 | 2007-02-21 | 公開日 | 2007-03-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Snapshots of the reaction mechanism of matrix metalloproteinases. ANGEW.CHEM.INT.ED.ENGL., 45, 2006
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2KVJ
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![BU of 2kvj by Molmil](/molmil-images/mine/2kvj) | NMR and MD solution structure of a Gamma-Methylated PNA duplex | 分子名称: | Gamma-Modified Peptide Nucleic Acid | 著者 | He, W, Crawford, M.J, Rapireddy, S, Madrid, M, Gil, R.R, Ly, D.H, Achim, C. | 登録日 | 2010-03-15 | 公開日 | 2010-05-12 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of a gamma-modified peptide nucleic acid duplex. Mol Biosyst, 6, 2010
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1RMZ
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![BU of 1rmz by Molmil](/molmil-images/mine/1rmz) | Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor NNGH at 1.3 A resolution | 分子名称: | CALCIUM ION, Macrophage metalloelastase, N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID, ... | 著者 | Bertini, I, Calderone, V, Fragai, M, Luchinat, C, Mangani, S, Terni, B. | 登録日 | 2003-11-28 | 公開日 | 2004-12-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Conformational variability of matrix metalloproteinases: beyond a single 3D structure. Proc.Natl.Acad.Sci.Usa, 102, 2005
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