1OS9
Binary enzyme-product complexes of human MMP12
Summary for 1OS9
Entry DOI | 10.2210/pdb1os9/pdb |
Related | 1JK3 1OS2 |
Descriptor | Macrophage metalloelastase, ZINC ION, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | matrix metalloproteinase, hydroxamic acid, mmp12, elastase, complex (elastase-inhibitor), metallo elastase, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P39900 |
Total number of polymer chains | 6 |
Total formula weight | 111495.11 |
Authors | Bertini, I.,Calderone, V.,Fragai, M.,Luchinat, C.,Mangani, S.,Terni, B. (deposition date: 2003-03-19, release date: 2003-08-05, Last modification date: 2023-08-16) |
Primary citation | Bertini, I.,Calderone, V.,Fragai, M.,Luchinat, C.,Mangani, S.,Terni, B. X-ray Structures of Binary and Ternary Enzyme-Product-Inhibitor Complexes of Matrix Metalloproteinases Angew.Chem.Int.Ed.Engl., 42:2673-2676, 2003 Cited by PubMed: 12813751DOI: 10.1002/anie.200350957 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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