1JK3
Crystal structure of human MMP-12 (Macrophage Elastase) at true atomic resolution
Summary for 1JK3
Entry DOI | 10.2210/pdb1jk3/pdb |
Descriptor | MACROPHAGE METALLOELASTASE, ZINC ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | matrix metalloproteinase, batimastat, bb94, hydroxamic acid, mmp12, elastase, complex (elastase-inhibitor), metallo elastase, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P39900 |
Total number of polymer chains | 1 |
Total formula weight | 18187.22 |
Authors | Lang, R.,Kocourek, A.,Braun, M.,Tschesche, H.,Huber, R.,Bode, W.,Maskos, K. (deposition date: 2001-07-11, release date: 2001-09-28, Last modification date: 2023-08-16) |
Primary citation | Lang, R.,Kocourek, A.,Braun, M.,Tschesche, H.,Huber, R.,Bode, W.,Maskos, K. Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure. J.Mol.Biol., 312:731-742, 2001 Cited by PubMed: 11575928DOI: 10.1006/jmbi.2001.4954 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.09 Å) |
Structure validation
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