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6TD5
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BU of 6td5 by Molmil
Leishmania tarentolae proteasome 20S subunit complexed with LXE408 and bortezomib
分子名称: N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, Proteasome endopeptidase complex, Proteasome subunit alpha type, ...
著者Srinivas, H.
登録日2019-11-07
公開日2020-08-26
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases.
J.Med.Chem., 63, 2020
5O1R
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BU of 5o1r by Molmil
human Fab 5H2 bound to NHBA-C3 from Neisseria meningitidis serogroup B
分子名称: 1,2-ETHANEDIOL, GNA2132, IGH@ protein, ...
著者Malito, E, Maritan, M.
登録日2017-05-19
公開日2018-05-30
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody.
PLoS ONE, 13, 2018
5NYX
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BU of 5nyx by Molmil
human Fab fragment 5H2 against NHBA from Neisseria meningitidis
分子名称: GLYCEROL, HEAVY CHAIN, LIGHT CHAIN, ...
著者Malito, E, Maritan, M.
登録日2017-05-12
公開日2018-05-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody.
PLoS ONE, 13, 2018
2IJM
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BU of 2ijm by Molmil
Crystal Structure of Focal Adhesion Kinase Domain with 2 molecules in the Asymmetric Unit Complexed with ADP and ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Focal Adhesion Kinase 1
著者Lee, C.C.
登録日2006-09-29
公開日2007-08-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.187 Å)
主引用文献Crystal Structure of Focal Adhesion Kinase Catalytic Domain Complexed with ATP and Novel 7H-Pyrrolo [2,3-d] pyrimidine Inhibitor Scaffolds
To be Published
1EI3
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BU of 1ei3 by Molmil
CRYSTAL STRUCTURE OF NATIVE CHICKEN FIBRINOGEN
分子名称: FIBRINOGEN
著者Yang, Z, Mochalkin, I, Veerapandian, L, Riley, M, Doolittle, R.F.
登録日2000-02-23
公開日2000-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Crystal structure of native chicken fibrinogen at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 97, 2000
7RUN
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BU of 7run by Molmil
Crystal structure of phosphorylated RET tyrosine kinase domain complexed with a pyrrolo[2,3-d]pyrimidine inhibitor.
分子名称: 1-(4-{(1s,3s)-3-[4-amino-5-(3-amino-4-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl}piperazin-1-yl)ethan-1-one, CHLORIDE ION, Proto-oncogene tyrosine-protein kinase receptor Ret
著者Lee, C.C, Spraggon, G.
登録日2021-08-17
公開日2022-01-19
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3- d ]pyrimidine RET Inhibitors.
Acs Med.Chem.Lett., 12, 2021
4BIG
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BU of 4big by Molmil
Crystal structure of the conserved staphylococcal antigen 1B, Csa1B
分子名称: UNCHARACTERIZED LIPOPROTEIN SAOUHSC_00053
著者Malito, E, Bottomley, M.J, Schluepen, C, Liberatori, S.
登録日2013-04-10
公開日2013-08-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.274 Å)
主引用文献Mining the Bacterial Unknown Proteome: Identification and Characterization of a Novel Family of Highly Conserved Protective Antigens in Staphylococcus Aureus
Biochem.J., 455, 2013
1B8K
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BU of 1b8k by Molmil
Neurotrophin-3 from Human
分子名称: PROTEIN (NEUROTROPHIN-3)
著者Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S.
登録日1999-02-01
公開日1999-02-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
1B8M
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BU of 1b8m by Molmil
BRAIN DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN-4
分子名称: PROTEIN (BRAIN DERIVED NEUROTROPHIC FACTOR), PROTEIN (NEUROTROPHIN-4)
著者Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S.
登録日1999-02-01
公開日1999-02-09
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
1B98
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BU of 1b98 by Molmil
NEUROTROPHIN 4 (HOMODIMER)
分子名称: CHLORIDE ION, PROTEIN (NEUROTROPHIN-4)
著者Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S.
登録日1999-02-22
公開日1999-02-26
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
6UIP
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BU of 6uip by Molmil
DYRK1A Kinase Domain in Complex with a 6-azaindole Derivative, GNF2133.
分子名称: 4-ethyl-N-{4-[1-(oxan-4-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]pyridin-2-yl}piperazine-1-carboxamide, Dual specificity tyrosine-phosphorylation-regulated kinase 1A
著者DiDonato, M, Spraggon, G.
登録日2019-10-01
公開日2020-03-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133.
J.Med.Chem., 63, 2020
2AFB
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BU of 2afb by Molmil
Crystal structure of 2-dehydro-3- deoxygluconokinase (EC 2.7.1.45) (tm0067) from THERMOTOGA MARITIMA at 2.05 A resolution
分子名称: 2-keto-3-deoxygluconate kinase, CALCIUM ION, NICKEL (II) ION
著者Joint Center for Structural Genomics (JCSG)
登録日2005-07-25
公開日2006-02-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution.
Proteins, 70, 2007
3LCT
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BU of 3lct by Molmil
Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALK tyrosine kinase receptor, GLYCEROL
著者Lee, C.C.
登録日2010-01-11
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem.J., 430, 2010
1ZX8
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BU of 1zx8 by Molmil
CRYSTAL STRUCTURE OF an atypical cyclophilin (peptidylprolyl cis-trans isomerase) (TM1367) FROM THERMOTOGA MARITIMA AT 1.90 A RESOLUTION
分子名称: NICKEL (II) ION, PENTAETHYLENE GLYCOL, hypothetical protein TM1367
著者Joint Center for Structural Genomics (JCSG)
登録日2005-06-07
公開日2005-07-26
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold.
Proteins, 63, 2006
3LCS
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BU of 3lcs by Molmil
Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
分子名称: ALK tyrosine kinase receptor, GLYCEROL, STAUROSPORINE
著者Lee, C.C.
登録日2010-01-11
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem.J., 430, 2010
1ZKG
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BU of 1zkg by Molmil
Crystal structure of Transcriptional regulator, TETR family (tm1030) from Thermotoga maritima at 2.30 A resolution
分子名称: UNKNOWN LIGAND, transcriptional regulator, TetR family
著者Joint Center for Structural Genomics (JCSG)
登録日2005-05-02
公開日2005-07-26
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function.
Proteins, 68, 2007
3L9P
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BU of 3l9p by Molmil
Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
分子名称: Anaplastic lymphoma kinase, GLYCEROL
著者Lee, C.
登録日2010-01-05
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem.J., 430, 2010
2FG0
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BU of 2fg0 by Molmil
Crystal structure of a putative gamma-d-glutamyl-l-diamino acid endopeptidase (npun_r0659) from nostoc punctiforme pcc 73102 at 1.79 A resolution
分子名称: COG0791: Cell wall-associated hydrolases (invasion-associated proteins), GLYCEROL
著者Joint Center for Structural Genomics (JCSG)
登録日2005-12-20
公開日2006-01-10
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Basis of Murein Peptide Specificity of a gamma-D-Glutamyl-L-Diamino Acid Endopeptidase.
Structure, 17, 2009
2EVR
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BU of 2evr by Molmil
CRYSTAL STRUCTURE OF A PUTATIVE GAMMA-D-GLUTAMYL-L-DIAMINO ACID ENDOPEPTIDASE (NPUN_R0659) FROM NOSTOC PUNCTIFORME PCC 73102 AT 1.60 A RESOLUTION
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COG0791: Cell wall-associated hydrolases (invasion-associated proteins), ...
著者Joint Center for Structural Genomics (JCSG)
登録日2005-10-31
公開日2005-11-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis of Murein Peptide Specificity of a gamma-D-Glutamyl-L-Diamino Acid Endopeptidase.
Structure, 17, 2009
1Z9F
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BU of 1z9f by Molmil
Crystal structure of single stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution
分子名称: Single-strand binding protein
著者Joint Center for Structural Genomics (JCSG)
登録日2005-04-01
公開日2005-04-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution.
Proteins, 63, 2006
2HBW
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BU of 2hbw by Molmil
Crystal structure of a putative endopeptidase (ava_3396) from anabaena variabilis atcc 29413 at 1.05 A resolution
分子名称: ACETATE ION, NLP/P60 protein, UNKNOWN LIGAND
著者Joint Center for Structural Genomics (JCSG)
登録日2006-06-14
公開日2006-08-08
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structural Basis of Murein Peptide Specificity of a gamma-D-Glutamyl-L-Diamino Acid Endopeptidase.
Structure, 17, 2009
2B8N
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BU of 2b8n by Molmil
Crystal structure of Glycerate kinase (EC 2.7.1.31) (tm1585) from THERMOTOGA MARITIMA at 2.70 A resolution
分子名称: glycerate kinase, putative
著者Joint Center for Structural Genomics (JCSG)
登録日2005-10-07
公開日2005-11-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold
Proteins, 65, 2006
1J5Y
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BU of 1j5y by Molmil
Crystal structure of transcriptional regulator (TM1602) from Thermotoga maritima at 2.3 A resolution
分子名称: NICKEL (II) ION, POTASSIUM ION, TRANSCRIPTIONAL REGULATOR, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2002-07-05
公開日2002-07-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a transcription regulator (TM1602) from Thermotoga maritima at 2.3 A resolution.
Proteins, 67, 2007
2ETS
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BU of 2ets by Molmil
CRYSTAL STRUCTURE OF A BACTERIAL DOMAIN OF UNKNOWN FUNCTION FROM DUF1798 FAMILY (MW1337) FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS AT 2.25 A RESOLUTION
分子名称: CHLORIDE ION, PHOSPHATE ION, hypothetical protein
著者Joint Center for Structural Genomics (JCSG)
登録日2005-10-27
公開日2005-11-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold.
Proteins, 71, 2008
2Y7S
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BU of 2y7s by Molmil
Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity
分子名称: FACTOR H BINDING PROTEIN
著者Malito, E, Spraggon, G, Bottomley, M.J.
登録日2011-02-01
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity.
Sci.Transl.Med, 3, 2011

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