8ELQ
 
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7KN5
 | | Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobodies VHH E and U | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | | 登録日 | 2020-11-04 | | 公開日 | 2021-01-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Science, 371, 2021
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7KN6
 | | Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH V and antibody Fab CC12.3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ... | | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | | 登録日 | 2020-11-04 | | 公開日 | 2021-01-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Science, 371, 2021
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7KN7
 | | Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH W and antibody Fab CC12.3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ... | | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | | 登録日 | 2020-11-04 | | 公開日 | 2021-01-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Science, 371, 2021
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8SIT
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8SIR
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8SIQ
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8SIS
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7U4M
 | | Crystal structure of human GPX4-U46C in complex with LOC1886 | | 分子名称: | 1,2-ETHANEDIOL, 4-methoxy-1H-indole-2-carbaldehyde, Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-28 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4K
 | | Crystal structure of human GPX4-U46C-R152H in complex with ML162 | | 分子名称: | 1,2-ETHANEDIOL, 2-chloro-N-(3-chloro-4-methoxyphenyl)-N-[(1R)-2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl]acetamide, Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Xia, X, Soni, R.K, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4I
 | | Crystal structure of human GPX4-U46C-R152H in complex with CDS9 | | 分子名称: | 2-bromo-N-[(thiophen-2-yl)methyl]acetamide, Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4L
 | | Crystal structure of human GPX4-U46C in complex with MAC-5576 | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, thiophene-2-carbaldehyde | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4J
 | | Crystal structure of human GPX4-U46C-R152H in complex with TMT10 | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION, ~{N}-(3-chloranyl-4-methoxy-phenyl)ethanamide | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4N
 | | Crystal structure of human GPX4-U46C in complex with RSL3 | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, methyl (1S,3R)-2-(chloroacetyl)-1-[4-(methoxycarbonyl)phenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Xia, X, Soni, R.K, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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8CWV
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8CWU
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8DGU
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8DGW
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8DGX
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8DGV
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5XNQ
 | | Crystal structures of human SALM5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Liu, H, Lin, Z, Xu, F. | | 登録日 | 2017-05-24 | | 公開日 | 2018-01-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Structural basis of SALM5-induced PTP delta dimerization for synaptic differentiation
Nat Commun, 9, 2018
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8JOU
 | | Fiber I and fiber-tail-adaptor of phage GP4 | | 分子名称: | Virion-associated phage protein, rope protein of phage GP4 | | 著者 | Liu, H, Chen, W. | | 登録日 | 2023-06-08 | | 公開日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Asymmetric Structure of Podophage GP4 Reveals a Novel Architecture of Three Types of Tail Fibers.
J.Mol.Biol., 435, 2023
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8JOV
 | | Portal-tail complex of phage GP4 | | 分子名称: | Portal protein, Putative tail fiber protein, Virion associated protein, ... | | 著者 | Liu, H, Chen, W. | | 登録日 | 2023-06-08 | | 公開日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Asymmetric Structure of Podophage GP4 Reveals a Novel Architecture of Three Types of Tail Fibers.
J.Mol.Biol., 435, 2023
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3MJK
 | | Structure of a growth factor precursor | | 分子名称: | Platelet-derived growth factor subunit A | | 著者 | Liu, H, He, X. | | 登録日 | 2010-04-12 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3NVQ
 | | Molecular mechanism of guidance cue recognition | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-C1, ... | | 著者 | Juo, Z, Liu, H, Shim, A, Focia, P, Chen, X, Garcia, C, He, X. | | 登録日 | 2010-07-08 | | 公開日 | 2010-09-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1.
Cell(Cambridge,Mass.), 142, 2010
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