7NHI
 
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1R20
 | | Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI06830 | | 分子名称: | ECDYSONE RECEPTOR, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE, ... | | 著者 | Billas, I.M.L, Iwema, T, Garnier, J.M, Mitschler, A, Rochel, N, Moras, D, Structural Proteomics in Europe (SPINE) | | 登録日 | 2003-09-25 | | 公開日 | 2003-11-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.
Nature, 426, 2003
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7NH4
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1R64
 | | The 2.2 A crystal structure of Kex2 protease in complex with Ac-Arg-Glu-Lys-boroArg peptidyl boronic acid inhibitor | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Holyoak, T, Kettner, C.A, Petsko, G.A, Fuller, R.S, Ringe, D. | | 登録日 | 2003-10-14 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis for Differences in Substrate Selectivity in Kex2 and Furin Protein Convertases
Biochemistry, 43, 2004
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7NH5
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2REI
 | | Kinase domain of human ephrin type-A receptor 7 (Epha7) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Ephrin type-A receptor 7 | | 著者 | Walker, J.R, Cuerrier, D, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2007-09-26 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Kinase Domain of Human Ephrin Type-A Receptor 7 (Epha7).
To be Published
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7NG7
 | | Src kinase bound to eCF506 trapped in inactive conformation | | 分子名称: | 1,2-ETHANEDIOL, Proto-oncogene tyrosine-protein kinase Src, tert-butyl (4-(4-amino-1-(2-(4-(dimethylamino)piperidin-1-yl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)carbamate | | 著者 | Lietha, D, Unciti-Broceta, A. | | 登録日 | 2021-02-08 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability.
Cancer Res., 81, 2021
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2RAR
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7MZ5
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7MZ6
 | | Cryo-EM structure of minimal TRPV1 with 1 perturbed PI | | 分子名称: | (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2021-05-24 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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2RAV
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1R7A
 | | Sucrose Phosphorylase from Bifidobacterium adolescentis | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, sucrose phosphorylase | | 著者 | Sprogoe, D, van den Broek, L.A.M, Mirza, O, Kastrup, J.S, Voragen, A.G.J, Gajhede, M, Skov, L.K. | | 登録日 | 2003-10-21 | | 公開日 | 2004-02-10 | | 最終更新日 | 2014-11-19 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis.
Biochemistry, 43, 2004
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1OAR
 | | Fv IgE SPE-7 in complex with Alizarin Red | | 分子名称: | 1,2-ETHANEDIOL, ALIZARIN RED, CACODYLATE ION, ... | | 著者 | James, L.C, Roversi, P, Tawfik, D. | | 登録日 | 2003-01-21 | | 公開日 | 2004-01-15 | | 最終更新日 | 2013-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
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7MZ9
 | | Cryo-EM structure of minimal TRPV1 with 1 partially bound RTX | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2021-05-24 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7MZB
 | | Cryo-EM structure of minimal TRPV1 with 3 bound RTX and 1 perturbed PI | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2021-05-24 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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2R6G
 | | The Crystal Structure of the E. coli Maltose Transporter | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Maltose transport system permease protein malF, Maltose transport system permease protein malG, ... | | 著者 | Oldham, M.L, Khare, D, Quiocho, F.A, Davidson, A.L, Chen, J. | | 登録日 | 2007-09-05 | | 公開日 | 2007-11-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of a catalytic intermediate of the maltose transporter.
Nature, 450, 2007
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7MZC
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7MZE
 | | Cryo-EM structure of minimal TRPV1 with 2 bound RTX in opposite pockets | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2021-05-24 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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1OAZ
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7MZA
 | | Cryo-EM structure of minimal TRPV1 with 2 bound RTX in adjacent pockets | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2021-05-24 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7NKZ
 | | Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis at 2.5 A resolution | | 分子名称: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, HEME B/C, MENAQUINONE-9, ... | | 著者 | Safarian, S, Wu, D, Krause, K.L, Michel, H. | | 登録日 | 2021-02-19 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB.
Nat Commun, 12, 2021
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7MZ7
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7MZD
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2REY
 | | Crystal structure of the PDZ domain of human dishevelled 2 (homologous to Drosophila dsh) | | 分子名称: | Segment polarity protein dishevelled homolog DVL-2 | | 著者 | Papagrigoriou, E, Gileadi, C, Elkins, J, Cooper, C, Ugochukwu, E, Turnbull, A, Pike, A.C.W, Gileadi, O, von Delft, F, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Doyle, D, Structural Genomics Consortium (SGC) | | 登録日 | 2007-09-27 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh).
To be Published
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2RF3
 | | Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles | | 分子名称: | 5'-d(CGCG(TCY)ATTCGCG)-3', SPERMINE, ZINC ION | | 著者 | Pallan, P.S, Ittig, D, Heroux, A, Wawrzak, Z, Leumann, C.J, Egli, M. | | 登録日 | 2007-09-27 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles.
Chem.Commun.(Camb.), 2008, 2008
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