2QW6
 
 | | Crystal structure of the C-terminal domain of an AAA ATPase from Enterococcus faecium DO | | 分子名称: | AAA ATPase, central region | | 著者 | Bonanno, J.B, Rutter, M, Bain, K.T, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-08-09 | | 公開日 | 2007-08-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the C-terminal domain of an AAA ATPase from Enterococcus faecium DO.
To be Published
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5OMG
 | | p38alpha in complex with pyrazolobenzothiazine inhibitor COXP4M12 | | 分子名称: | 3-(4-fluorophenyl)-4-methyl-1~{H}-pyrazolo[4,3-c][1,2]benzothiazine 5,5-dioxide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Buehrmann, M, Rauh, D. | | 登録日 | 2017-07-31 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38 alpha MAPK inhibitors.
Biochem.Biophys.Res.Commun., 511, 2019
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5KHT
 | | Crystal structure of the N-terminal fragment of tropomyosin isoform Tpm1.1 at 1.5 A resolution | | 分子名称: | DI(HYDROXYETHYL)ETHER, Tropomyosin alpha-1 chain,General control protein GCN4 | | 著者 | Kostyukova, A.S, Krieger, I, Yoon, Y.-H, Tolkatchev, D, Samatey, F.A. | | 登録日 | 2016-06-15 | | 公開日 | 2017-06-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.4964 Å) | | 主引用文献 | Structural destabilization of tropomyosin induced by the cardiomyopathy-linked mutation R21H.
Protein Sci., 27, 2018
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7NJE
 | | gamma(S)-crystallin 9-site deamidation mutant grown inside HARE serial crystallography chip | | 分子名称: | Gamma-crystallin S | | 著者 | Norton-Baker, B, Mehrabi, P, Boger, J, Schonherr, R, von Stetten, D, Schikora, H, Martin, R.W, Miller, R.J.D, Redecke, L, Schulz, E.C. | | 登録日 | 2021-02-16 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip.
Acta Crystallogr D Struct Biol, 77, 2021
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1MUW
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7NJH
 | | HEX1 (in cellulo) grown inside HARE serial crystallography chip | | 分子名称: | Woronin body major protein | | 著者 | Norton-Baker, B, Mehrabi, P, Boger, J, Schonherr, R, von Stetten, D, Schikora, H, Martin, R.W, Miller, R.J.D, Redecke, L, Schulz, E.C. | | 登録日 | 2021-02-16 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip.
Acta Crystallogr D Struct Biol, 77, 2021
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5JZ9
 | | Crystal structure of HsaD bound to 3,5-dichloro-4-hydroxybenzenesulphonic acid | | 分子名称: | 3,5-dichloro-4-hydroxybenzene-1-sulfonic acid, 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | | 著者 | Ryan, A, Polycarpou, E, Lack, N.A, Evangelopoulos, D, Sieg, C, Halman, A, Bhakta, S, Sinclair, A, Eleftheriadou, O, McHugh, T.D, Keany, S, Lowe, E, Ballet, R, Abihammad, A, Ciulli, A, Sim, E. | | 登録日 | 2016-05-16 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach.
Br. J. Pharmacol., 174, 2017
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7NJG
 | | Xylose isomerase grown inside HARE serial crystallography chip | | 分子名称: | COBALT (II) ION, Xylose isomerase | | 著者 | Norton-Baker, B, Mehrabi, P, Boger, J, Schonherr, R, von Stetten, D, Schikora, H, Martin, R.W, Miller, R.J.D, Redecke, L, Schulz, E.C. | | 登録日 | 2021-02-16 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip.
Acta Crystallogr D Struct Biol, 77, 2021
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1MY6
 | | The 1.6 A Structure of Fe-Superoxide Dismutase from the thermophilic cyanobacterium Thermosynechococcus elongatus : Correlation of EPR and Structural Characteristics | | 分子名称: | FE (III) ION, Iron (III) Superoxide Dismutase | | 著者 | Yoshida, S.M, Cascio, D, Sawaya, M.R, Yeates, T.O, Kerfeld, C.A. | | 登録日 | 2002-10-03 | | 公開日 | 2003-07-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The 1.6 A resolution structure of Fe-superoxide dismutase from the thermophilic cyanobacterium Thermosynechococcus elongatus.
J.BIOL.INORG.CHEM., 8, 2003
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2R18
 | | Structural insights into the multifunctional protein VP3 of Birnaviruses | | 分子名称: | Capsid assembly protein VP3 | | 著者 | Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N. | | 登録日 | 2007-08-22 | | 公開日 | 2008-02-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insights into the multifunctional protein VP3 of birnaviruses.
Structure, 16, 2008
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7NJI
 | | HEX1 (in cellulo) loaded on HARE serial crystallography chip | | 分子名称: | Woronin body major protein | | 著者 | Norton-Baker, B, Mehrabi, P, Boger, J, Schonherr, R, von Stetten, D, Schikora, H, Martin, R.W, Miller, R.J.D, Redecke, L, Schulz, E.C. | | 登録日 | 2021-02-16 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip.
Acta Crystallogr D Struct Biol, 77, 2021
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1QYG
 | | ANTI-COCAINE ANTIBODY M82G2 COMPLEXED WITH BENZOYLECGONINE | | 分子名称: | 3-(BENZOYLOXY)-8-METHYL-8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID, FAB M82G2, HEAVY CHAIN, ... | | 著者 | Pozharski, E, Hewagama, A, Shanafelt, A, Petsko, G, Ringe, D. | | 登録日 | 2003-09-10 | | 公開日 | 2003-09-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2.
J.Mol.Biol., 349, 2005
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5K2C
 | | 1.9 angstrom A2a adenosine receptor structure with sulfur SAD phasing and phase extension using XFEL data | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a/Soluble cytochrome b562 chimera, ... | | 著者 | Batyuk, A, Galli, L, Ishchenko, A, Han, G.W, Gati, C, Popov, P, Lee, M.-Y, Stauch, B, White, T.A, Barty, A, Aquila, A, Hunter, M.S, Liang, M, Boutet, S, Pu, M, Liu, Z.-J, Nelson, G, James, D, Li, C, Zhao, Y, Spence, J.C.H, Liu, W, Fromme, P, Katritch, V, Weierstall, U, Stevens, R.C, Cherezov, V, GPCR Network (GPCR) | | 登録日 | 2016-05-18 | | 公開日 | 2016-09-21 | | 最終更新日 | 2018-11-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Sci Adv, 2, 2016
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7NKU
 | | diazaborine bound Drg1(AFG2) | | 分子名称: | 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL, ATPase family gene 2 protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Prattes, M, Bergler, H, Haselbach, D. | | 登録日 | 2021-02-19 | | 公開日 | 2021-06-23 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine.
Nat Commun, 12, 2021
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1QZ7
 | | Beta-catenin binding domain of Axin in complex with beta-catenin | | 分子名称: | Axin, Beta-catenin | | 著者 | Xing, Y, Clements, W.K, Kimelman, D, Xu, W. | | 登録日 | 2003-09-15 | | 公開日 | 2003-11-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a beta-catenin/Axin complex suggests a mechanism for the {beta}-catenin destruction complex
GENES DEV., 17, 2003
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2QV0
 | | Crystal structure of the response regulatory domain of protein mrkE from Klebsiella pneumoniae | | 分子名称: | Protein mrkE | | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Iizuka, I, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-08-07 | | 公開日 | 2007-08-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the response regulatory domain of protein mrkE from Klebsiella pneumoniae.
To be Published
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1NFB
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2QRV
 | | Structure of Dnmt3a-Dnmt3L C-terminal domain complex | | 分子名称: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Jia, D, Cheng, X. | | 登録日 | 2007-07-29 | | 公開日 | 2007-12-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.
Nature, 449, 2007
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1NJ6
 | | Crystal structure of Prolyl-tRNA Synthetase from Methanothermobacter thermautotrophicus bound to alanine sulfamoyl adenylate | | 分子名称: | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Proline-tRNA Synthetase, ... | | 著者 | Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A. | | 登録日 | 2002-12-30 | | 公開日 | 2003-03-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
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1NIG
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1NIU
 | | ALANINE RACEMASE WITH BOUND INHIBITOR DERIVED FROM L-CYCLOSERINE | | 分子名称: | Alanine Racemase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE | | 著者 | Fenn, T.D, Stamper, G.F, Morollo, A.A, Ringe, D. | | 登録日 | 2002-12-26 | | 公開日 | 2003-09-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A side reaction of alanine racemase: transamination of cycloserine.
Biochemistry, 42, 2003
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1SFT
 | | ALANINE RACEMASE | | 分子名称: | ACETATE ION, ALANINE RACEMASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Shaw, J.P, Petsko, G.A, Ringe, D. | | 登録日 | 1996-09-20 | | 公開日 | 1997-02-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-A resolution.
Biochemistry, 36, 1997
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1S79
 | | Solution structure of the central RRM of human La protein | | 分子名称: | Lupus La protein | | 著者 | Alfano, C, Sanfelice, D, Babon, J, Kelly, G, Jacks, A, Curry, S, Conte, M.R. | | 登録日 | 2004-01-29 | | 公開日 | 2004-04-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein.
Nat.Struct.Mol.Biol., 11, 2004
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5KAO
 | | Crystal structure of wild type HIV-1 protease in complex with GRL-10413 | | 分子名称: | [(3~{a}~{S},4~{R},6~{a}~{R})-2,3,3~{a},4,5,6~{a}-hexahydrofuro[2,3-b]furan-4-yl] ~{N}-[(2~{S},3~{R})-1-(3-chloranyl-4-methoxy-phenyl)-4-[(4-methoxyphenyl)sulfonyl-(2-methylpropyl)amino]-3-oxidanyl-butan-2-yl]carbamate, protease | | 著者 | Yedidi, R.S, Delino, N.S, Das, D, Kaufman, J.D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. | | 登録日 | 2016-06-01 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A Modified P1 Moiety Enhances In Vitro Antiviral Activity against Various Multidrug-Resistant HIV-1 Variants and In Vitro Central Nervous System Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413.
Antimicrob.Agents Chemother., 60, 2016
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1S9K
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