7XS8
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7XSA
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7XSB
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7X2M
| Crystal structure of nanobody 1-2C7 with SARS-CoV-2 RBD | 分子名称: | 1-2C7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1 | 著者 | Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X. | 登録日 | 2022-02-25 | 公開日 | 2022-12-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses. Nat Commun, 13, 2022
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7X2J
| Crystal structure of nanobody Nb70 with SARS-CoV RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nb70, Spike protein S1 | 著者 | Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X. | 登録日 | 2022-02-25 | 公開日 | 2022-12-21 | 最終更新日 | 2023-06-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses. Nat Commun, 13, 2022
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7X2K
| Crystal structure of nanobody Nb70 with antibody 1F11 fab and SARS-CoV-2 RBD | 分子名称: | 1F11-H, 1F11-L, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X. | 登録日 | 2022-02-25 | 公開日 | 2022-12-21 | 最終更新日 | 2023-06-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses. Nat Commun, 13, 2022
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7X2L
| Crystal structure of nanobody 3-2A2-4 with SARS-CoV-2 RBD | 分子名称: | Nanobody 3-2A2-4, Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X. | 登録日 | 2022-02-25 | 公開日 | 2022-12-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses. Nat Commun, 13, 2022
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6JWP
| crystal structure of EGOC | 分子名称: | Ego2, GTP-binding protein GTR1, GTP-binding protein GTR2, ... | 著者 | Zhang, T, Ding, J. | 登録日 | 2019-04-21 | 公開日 | 2019-12-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases. Sci Adv, 5, 2019
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7YHK
| Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5 | 分子名称: | 12H5 heavy chain, 12H5 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zheng, Q, Li, S, Li, T, Xue, W, Sun, H. | 登録日 | 2022-07-13 | 公開日 | 2022-08-17 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. Nat Commun, 13, 2022
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8GVJ
| Crystal structure of cMET kinase domain bound by D6808 | 分子名称: | (1^4Z,5^2E)-6^3-(trifluoromethyl)-5^1,5^6-dihydro-1^1H-8-aza-2(3,6)-quinolina-5(1,3)-pyridazina-1(4,1)-pyrazola-6(1,4)-benzenacyclododecaphane-5^6,7-dione, Hepatocyte growth factor receptor | 著者 | Chen, Y.H, Qu, L.Z. | 登録日 | 2022-09-15 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J.Med.Chem., 65, 2022
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7WRO
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7WR8
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7XNS
| SARS-CoV-2 Omicron BA.2.12.1 variant spike | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Wang, X, Wang, L. | 登録日 | 2022-04-29 | 公開日 | 2022-07-13 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Nature, 608, 2022
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7XIX
| SARS-CoV-2 Omicron BA.2 variant spike (state 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Wang, X, Wang, L. | 登録日 | 2022-04-14 | 公開日 | 2022-07-13 | 最終更新日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Nature, 608, 2022
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7XNQ
| SARS-CoV-2 Omicron BA.4 variant spike | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Wang, X, Wang, L. | 登録日 | 2022-04-29 | 公開日 | 2022-07-13 | 最終更新日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Nature, 608, 2022
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7XIY
| SARS-CoV-2 Omicron BA.3 variant spike | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Wang, X, Wang, L. | 登録日 | 2022-04-14 | 公開日 | 2022-07-13 | 最終更新日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Nature, 608, 2022
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7XIW
| SARS-CoV-2 Omicron BA.2 variant spike (state 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Wang, X, Wang, L. | 登録日 | 2022-04-14 | 公開日 | 2022-07-13 | 最終更新日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Nature, 608, 2022
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7XIZ
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7XNR
| SARS-CoV-2 Omicron BA.2.13 variant spike | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Wang, X, Wang, L. | 登録日 | 2022-04-29 | 公開日 | 2022-07-13 | 最終更新日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Nature, 608, 2022
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7X6A
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7Y5K
| Crystal structure of human CAF-1 core complex in spacegroup C2221 | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ... | 著者 | Liu, C.P, Wang, M.Z, Xu, R.M. | 登録日 | 2022-06-17 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7Y61
| Cryo-EM structure of the two CAF1LCs bound right-handed Di-tetrasome | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | 著者 | Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. | 登録日 | 2022-06-18 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7Y5V
| Cryo-EM structure of the dimeric human CAF1LC-H3-H4 complex | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | 著者 | Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M. | 登録日 | 2022-06-17 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7Y5O
| Crystal structure of human CAF-1 core complex in spacegroup P21 | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ... | 著者 | Liu, C.P, Wang, M.Z, Xu, R.M. | 登録日 | 2022-06-17 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.57 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7Y5U
| Cryo-EM structure of the monomeric human CAF1LC-H3-H4 complex | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | 著者 | Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. | 登録日 | 2022-06-17 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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