8CDS
 
 | | Crystal structure of the xhNup93-Nb4i VHH antibody | | 分子名称: | 1,2-ETHANEDIOL, 5-Nup93 inhibitory VHH antibody, DI(HYDROXYETHYL)ETHER | | 著者 | Guttler, T, Colom, M.S, Gorlich, D. | | 登録日 | 2023-02-01 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies.
Embo J., 43, 2024
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3NRO
 | | Crystal Structure of putative transcriptional factor Lmo1026 from Listeria monocytogenes (FRAGMENT 52-321), Northeast Structural Genomics Consortium Target LmR194 | | 分子名称: | Lmo1026 protein | | 著者 | Kuzin, A, Su, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2010-06-30 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Northeast Structural Genomics Consortium Target LmR194
To be Published
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7AJT
 | | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | | 著者 | Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. | | 登録日 | 2020-09-29 | | 公開日 | 2020-12-30 | | 最終更新日 | 2021-02-03 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Mol.Cell, 81, 2021
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8COD
 | | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Mus musculus in complex with inosine | | 分子名称: | Adenosylhomocysteinase, INOSINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Saleem-Batcha, R, Popadic, D, Koeppl, L.H, Andexer, J.N. | | 登録日 | 2023-02-27 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Mus musculus in complex with inosine
To Be Published
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7B3B
 | | Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -3 (structure 1) | | 分子名称: | DNA/RNA (5'-R(P*CP*UP*AP*CP*GP*CP*G)-D(P*(RMP))-R(P*UP*G)-3'), Non-structural protein 7, Non-structural protein 8, ... | | 著者 | Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. | | 登録日 | 2020-11-30 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Mechanism of SARS-CoV-2 polymerase stalling by remdesivir.
Nat Commun, 12, 2021
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8OV9
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8P1Y
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8CMA
 | | SARS-CoV-2 Delta-RBD complexed with BA.4/5-35 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BA.4/5-35 heavy chain, BA.4/5-35 light chain, ... | | 著者 | Zhou, D, Ren, J, Stuart, D.I. | | 登録日 | 2023-02-18 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection.
Nat Commun, 15, 2024
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8CMO
 | | Cryo-EM structure of the Photosystem I - LHCI supercomplex from Coelastrella sp. | | 分子名称: | (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, ... | | 著者 | Fadeeva, M, Klaiman, D, Nelson, N. | | 登録日 | 2023-02-20 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Cryo-EM structure of the Photosystem I - LHCI supercomplex from Coelastrella sp.
To Be Published
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7AWC
 | | Crystal structure of Peroxisome proliferator-activated receptor gamma (PPARG)in complex with rosiglitazone | | 分子名称: | 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), GLYCEROL, ... | | 著者 | Chaikuad, A, Merk, D, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2020-11-06 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Endogenous vitamin E metabolites mediate allosteric PPAR gamma activation with unprecedented co-regulatory interactions.
Cell Chem Biol, 28, 2021
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8P1Z
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7AOB
 | | Crystal structure of Thermaerobacter marianensis malate dehydrogenase | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Bertrand, Q, Lasalle, L, Girard, E, Madern, D. | | 登録日 | 2020-10-14 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Crystal structure of Thermaerobacter marianensis malate dehydrogenase
To Be Published
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8C67
 | | Crystal structure of Ab25 Fab | | 分子名称: | antibody 25 heavy chain, antibody 25 light chain | | 著者 | Nyblom, M, Izadi, A, Tang, D, Bahnan, W, Happonen, L, Malmstroem, J, Shannon, O, Malmstroem, L, Nordenfelt, P. | | 登録日 | 2023-01-11 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Engineering of IgG1 hinge to the flexible IgG3 hinge enhances immune defense against streptococci
To Be Published
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8OX2
 | | BRICHOS trimer | | 分子名称: | Pulmonary surfactant-associated protein C | | 著者 | Ghosh, D, Torres, F, Guentert, P, Riek, R. | | 登録日 | 2023-04-30 | | 公開日 | 2024-06-26 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The inhibitory action of the chaperone BRICHOS against the alpha-Synuclein secondary nucleation pathway at near-atomic resolution
To Be Published
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8PCE
 | | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 250 ms | | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION | | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | | 登録日 | 2023-06-11 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
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8PCT
 | | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 2500 ms | | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | | 登録日 | 2023-06-11 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
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8PCA
 | | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 50 ms | | 分子名称: | Beta-lactamase, SULFATE ION | | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | | 登録日 | 2023-06-11 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
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8PCD
 | | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 150 ms | | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION | | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | | 登録日 | 2023-06-11 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
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8PCP
 | | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 250 ms | | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | | 登録日 | 2023-06-11 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
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8PCM
 | | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 80 ms | | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | | 登録日 | 2023-06-11 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
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8PCR
 | | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 750 ms | | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | | 登録日 | 2023-06-11 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
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8P8M
 | | Yeast 60S ribosomal subunit, RPL39 deletion | | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Rabl, J, Banerjee, A, Boehringer, D, Zavolan, M. | | 登録日 | 2023-06-01 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Yeast 60S ribosomal subunit, RPL39 deletion
To Be Published
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8OVI
 | | BRICHOS monomer | | 分子名称: | Pulmonary surfactant-associated protein C (Fragment) | | 著者 | Ghosh, D, Torres, F, Guentert, P, Riek, R. | | 登録日 | 2023-04-26 | | 公開日 | 2024-06-26 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The inhibitory action of the chaperone BRICHOS against the alpha-Synuclein secondary nucleation pathway at near-atomic resolution
To Be Published
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8PCI
 | | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 5000 ms | | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION | | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | | 登録日 | 2023-06-11 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
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8P7E
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