6CFU
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6CH0
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![BU of 6ch0 by Molmil](/molmil-images/mine/6ch0) | Structure of the Quorum Quenching lactonase from Alicyclobacillus acidoterrestris bound to a glycerol molecule | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, COBALT (II) ION, ... | 著者 | Bergonzi, C, Schwab, M, Naik, T, Daude, D, Chabriere, E, Elias, M. | 登録日 | 2018-02-21 | 公開日 | 2018-08-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties. Sci Rep, 8, 2018
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7XJV
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![BU of 7xjv by Molmil](/molmil-images/mine/7xjv) | Crystal Structure of Alpha-1,3-mannosyltransferase MNT2 from Saccharomyces cerevisiae, Mn/GDP-mannose form | 分子名称: | Alpha-1,3-mannosyltransferase MNT2, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, ... | 著者 | Hira, D, Kadooka, C, Oka, T. | 登録日 | 2022-04-18 | 公開日 | 2023-05-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of Alpha-1,3-mannosyltransferase MNT2 from Saccharomyces cerevisiae, Mn/GDP-mannose form To Be Published
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7XPI
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![BU of 7xpi by Molmil](/molmil-images/mine/7xpi) | Structure of a oxidoreductase | 分子名称: | Apoptosis inducing factor mitochondria associated 2, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Lv, Y, Sun, Q, Wang, Q, Zhu, D. | 登録日 | 2022-05-04 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into FSP1 catalysis and ferroptosis inhibition. Nat Commun, 14, 2023
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7XP9
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7XPC
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6CPE
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![BU of 6cpe by Molmil](/molmil-images/mine/6cpe) | Structure of apo, dephosphorylated Aurora A (122-403) in an active conformation | 分子名称: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Aurora kinase A | 著者 | Otten, R, Kutter, S, Buosi, V, Padua, R.A.P, Kern, D. | 登録日 | 2018-03-13 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Dynamics of human protein kinase Aurora A linked to drug selectivity. Elife, 7, 2018
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7KXT
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![BU of 7kxt by Molmil](/molmil-images/mine/7kxt) | Crystal structure of human EED | 分子名称: | 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine, Polycomb protein EED, UNKNOWN ATOM OR ION | 著者 | Zhu, L, Dong, A, Du, D, Liu, Y, Luo, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2020-12-04 | 公開日 | 2021-02-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction. J.Med.Chem., 64, 2021
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7JJM
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![BU of 7jjm by Molmil](/molmil-images/mine/7jjm) | Crystal structure of Importin alpha 2 in complex with LSD1 NLS | 分子名称: | CHLORIDE ION, Importin subunit alpha-1, Lysine-specific histone demethylase 1A | 著者 | Tu, W.J, McGuaig, R, Tan, H.Y.A, Hardy, C, Seddiki, N, Ali, S, Dahlstrom, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. | 登録日 | 2020-07-27 | 公開日 | 2020-08-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
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6BVB
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![BU of 6bvb by Molmil](/molmil-images/mine/6bvb) | Crystal structure of HIF-2alpha-pVHL-elongin B-elongin C | 分子名称: | Elongin-B, Elongin-C, Hypoxia-Inducible Factor 2 alpha, ... | 著者 | Tarade, D, Ohh, M, Lee, J.E. | 登録日 | 2017-12-12 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | HIF-2 alpha-pVHL complex reveals broad genotype-phenotype correlations in HIF-2 alpha-driven disease. Nat Commun, 9, 2018
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6BW1
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![BU of 6bw1 by Molmil](/molmil-images/mine/6bw1) | Hendra virus W protein C-terminus in complex with Importin alpha 1 | 分子名称: | Importin subunit alpha-1, Protein W | 著者 | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | 登録日 | 2017-12-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
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6BXH
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![BU of 6bxh by Molmil](/molmil-images/mine/6bxh) | Menin in complex with MI-853 | 分子名称: | 1-{2-[4-(fluoroacetyl)piperazin-1-yl]ethyl}-4-methyl-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile, DIMETHYL SULFOXIDE, Menin, ... | 著者 | Borkin, D, Klossowski, S, Pollock, J, Linhares, B, Cierpicki, T, Grembecka, J. | 登録日 | 2017-12-18 | 公開日 | 2018-11-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.445 Å) | 主引用文献 | Menin in complex with MI-853 To Be Published
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6BX7
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![BU of 6bx7 by Molmil](/molmil-images/mine/6bx7) | Crystal Structure of Human Protocadherin-1 EC1-4 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, Protocadherin-1 | 著者 | Modak, D, Sotomayor, M. | 登録日 | 2017-12-17 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Identification of an adhesive interface for the non-clustered delta 1 protocadherin-1 involved in respiratory diseases. Commun Biol, 2, 2019
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2JB2
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![BU of 2jb2 by Molmil](/molmil-images/mine/2jb2) | The structure of L-amino acid oxidase from Rhodococcus opacus in complex with L-phenylalanine. | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, L-AMINO ACID OXIDASE, PHENYLALANINE | 著者 | Faust, A, Niefind, K, Hummel, W, Schomburg, D. | 登録日 | 2006-12-01 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The Structure of a Bacterial L-Amino Acid Oxidase from Rhodococcus Opacus Gives New Evidence for the Hydride Mechanism for Dehydrogenation J.Mol.Biol., 367, 2007
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7Y35
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![BU of 7y35 by Molmil](/molmil-images/mine/7y35) | Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex | 分子名称: | Abaloparatide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhai, X, Mao, C, Shen, Q, Zang, S, Shen, D, Zhang, H, Chen, Z, Wang, G, Zhang, C, Zhang, Y, Liu, Z. | 登録日 | 2022-06-09 | 公開日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex To Be Published
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7Y36
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![BU of 7y36 by Molmil](/molmil-images/mine/7y36) | Cryo-EM structure of the Teriparatide-bound human PTH1R-Gs complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, HYDROXIDE ION, ... | 著者 | Zhai, X, Mao, C, Shen, Q, Zang, S, Shen, D, Zhang, H, Chen, Z, Wang, G, Zhang, C, Zhang, Y, Liu, Z. | 登録日 | 2022-06-10 | 公開日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structure of the Teriparatide-bound human PTH1R-Gs complex to be published
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3U1S
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![BU of 3u1s by Molmil](/molmil-images/mine/3u1s) | Crystal structure of human Fab PGT145, a broadly reactive and potent HIV-1 neutralizing antibody | 分子名称: | Fab PGT145 Heavy chain, Fab PGT145 Light chain, GLYCEROL, ... | 著者 | Julien, J.-P, Diwanji, D, Burton, D.R, Wilson, I.A. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480, 2011
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6BYW
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![BU of 6byw by Molmil](/molmil-images/mine/6byw) | Structure of GoxA from Pseudoalteromonas luteoviolacea | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GoxA, ... | 著者 | Yukl, E.T, Avalos, D. | 登録日 | 2017-12-21 | 公開日 | 2018-02-14 | 最終更新日 | 2018-02-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure and Enzymatic Properties of an Unusual Cysteine Tryptophylquinone-Dependent Glycine Oxidase from Pseudoalteromonas luteoviolacea. Biochemistry, 57, 2018
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6BZM
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![BU of 6bzm by Molmil](/molmil-images/mine/6bzm) | GFGNFGTS from low-complexity/FG repeat domain of Nup98, residues 116-123 | 分子名称: | Nuclear pore complex protein Nup98-Nup96 | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Chong, L, Gonen, T, Eisenberg, D.S. | 登録日 | 2017-12-24 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.9 Å) | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
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6C1E
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![BU of 6c1e by Molmil](/molmil-images/mine/6c1e) | NavAb NormoPP mutant | 分子名称: | (3ALPHA,5ALPHA,7ALPHA,8ALPHA,12ALPHA,14BETA,17ALPHA)-3,7,12-TRIHYDROXYCHOL-1-EN-24-AMIDE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 5-BETA-24-NOR-CHOLANE-3(ALPHA),7(ALPHA),12(ALPHA)-TRIOL, ... | 著者 | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | 登録日 | 2018-01-04 | 公開日 | 2018-05-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structural basis for gating pore current in periodic paralysis. Nature, 557, 2018
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6C2W
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![BU of 6c2w by Molmil](/molmil-images/mine/6c2w) | Crystal structure of human prothrombin mutant S101C/A470C | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Prothrombin, ... | 著者 | Chinnaraj, M, Chen, Z, Pelc, L, Grese, Z, Bystranowska, D, Di Cera, E, Pozzi, N. | 登録日 | 2018-01-09 | 公開日 | 2018-02-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (4.12 Å) | 主引用文献 | Structure of prothrombin in the closed form reveals new details on the mechanism of activation. Sci Rep, 8, 2018
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2JB1
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![BU of 2jb1 by Molmil](/molmil-images/mine/2jb1) | The L-amino acid oxidase from Rhodococcus opacus in complex with L- alanine | 分子名称: | ALANINE, FLAVIN-ADENINE DINUCLEOTIDE, L-AMINO ACID OXIDASE | 著者 | Faust, A, Niefind, K, Hummel, W, Schomburg, D. | 登録日 | 2006-12-01 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The Structure of a Bacterial L-Amino Acid Oxidase from Rhodococcus Opacus Gives New Evidence for the Hydride Mechanism for Dehydrogenation J.Mol.Biol., 367, 2007
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6CAA
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![BU of 6caa by Molmil](/molmil-images/mine/6caa) | CryoEM structure of human SLC4A4 sodium-coupled acid-base transporter NBCe1 | 分子名称: | Electrogenic sodium bicarbonate cotransporter 1 | 著者 | Huynh, K.W, Jiang, J, Abuladze, N, Tsirulnikov, K, Kao, L, Shao, X, Newman, D, Azimov, R, Pushkin, A, Zhou, Z.H, Kurtz, I. | 登録日 | 2018-01-29 | 公開日 | 2018-03-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1. Nat Commun, 9, 2018
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5UGQ
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![BU of 5ugq by Molmil](/molmil-images/mine/5ugq) | Crystal Structure of Hip1 (Rv2224c) | 分子名称: | Carboxylesterase A | 著者 | Naffin-Olivos, J.L, Daab, A, White, A, Goldfarb, N, Milne, A.C, Liu, D, Dunn, B.M, Rengarajan, J, Petsko, G.A, Ringe, D. | 登録日 | 2017-01-09 | 公開日 | 2017-04-12 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (2.609 Å) | 主引用文献 | Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c). Biochemistry, 56, 2017
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6BQH
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![BU of 6bqh by Molmil](/molmil-images/mine/6bqh) | Crystal structure of 5-HT2C in complex with ritanserin | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-hydroxytryptamine receptor 2C,Soluble cytochrome b562, 6-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one, ... | 著者 | Peng, Y, McCorvy, J.D, Harpsoe, K, Lansu, K, Yuan, S, Popov, P, Qu, L, Pu, M, Che, T, Nikolajse, L.F, Huang, X.P, Wu, Y, Shen, L, Bjorn-Yoshimoto, W.E, Ding, K, Wacker, D, Han, G.W, Cheng, J, Katritch, V, Jensen, A.A, Hanson, M.A, Zhao, S, Gloriam, D.E, Roth, B.L, Stevens, R.C, Liu, Z. | 登録日 | 2017-11-27 | 公開日 | 2018-02-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology. Cell, 172, 2018
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