8E9G
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![BU of 8e9g by Molmil](/molmil-images/mine/8e9g) | Mycobacterial respiratory complex I with both quinone positions modelled | 分子名称: | (2R)-3-{[(R)-hydroxy({(1S,2R,3R,4R,5S,6S)-3,4,5-trihydroxy-2-(alpha-D-mannopyranosyloxy)-6-[(6-O-undecanoyl-beta-D-mannopyranosyl)oxy]cyclohexyl}oxy)phosphoryl]oxy}-2-(octanoyloxy)propyl undecanoate, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | 著者 | Liang, Y, Rubinstein, J.L. | 登録日 | 2022-08-26 | 公開日 | 2022-10-12 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structure of mycobacterial respiratory complex I. Proc.Natl.Acad.Sci.USA, 120, 2023
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2QN2
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![BU of 2qn2 by Molmil](/molmil-images/mine/2qn2) | Glycogen Phosphorylase b in complex with Maslinic Acid | 分子名称: | Glycogen phosphorylase, muscle form, maslinic acid | 著者 | Zographos, S.E, Leonidas, D.D, Alexacou, K.-M, Hayes, J, Oikonomakos, N.G. | 登録日 | 2007-07-17 | 公開日 | 2008-06-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | 主引用文献 | Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies J.Med.Chem., 51, 2008
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5XNP
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![BU of 5xnp by Molmil](/molmil-images/mine/5xnp) | Crystal structures of human SALM5 in complex with human PTPdelta | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Liu, H, Lin, Z, Xu, F. | 登録日 | 2017-05-24 | 公開日 | 2018-01-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.729 Å) | 主引用文献 | Structural basis of SALM5-induced PTP delta dimerization for synaptic differentiation Nat Commun, 9, 2018
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5XNQ
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![BU of 5xnq by Molmil](/molmil-images/mine/5xnq) | Crystal structures of human SALM5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Liu, H, Lin, Z, Xu, F. | 登録日 | 2017-05-24 | 公開日 | 2018-01-24 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Structural basis of SALM5-induced PTP delta dimerization for synaptic differentiation Nat Commun, 9, 2018
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1CLK
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![BU of 1clk by Molmil](/molmil-images/mine/1clk) | CRYSTAL STRUCTURE OF STREPTOMYCES DIASTATICUS NO.7 STRAIN M1033 XYLOSE ISOMERASE AT 1.9 A RESOLUTION WITH PSEUDO-I222 SPACE GROUP | 分子名称: | COBALT (II) ION, MAGNESIUM ION, XYLOSE ISOMERASE | 著者 | Niu, L, Teng, M, Zhu, X, Gong, W. | 登録日 | 1999-04-29 | 公開日 | 2000-05-03 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of xylose isomerase from Streptomyces diastaticus no. 7 strain M1033 at 1.85 A resolution. Acta Crystallogr.,Sect.D, 56, 2000
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3UAS
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![BU of 3uas by Molmil](/molmil-images/mine/3uas) | Cytochrome P450 2B4 covalently bound to the mechanism-based inactivator 9-ethynylphenanthrene | 分子名称: | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Gay, S.C, Zhang, H, Shah, M.B, Stout, C.D, Halpert, J.R, Hollenberg, P.F. | 登録日 | 2011-10-21 | 公開日 | 2013-01-09 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.939 Å) | 主引用文献 | Potent Mechanism-Based Inactivation of Cytochrome P450 2B4 by 9-Ethynylphenanthrene: Implications for Allosteric Modulation of Cytochrome P450 Catalysis. Biochemistry, 52, 2013
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3FPM
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![BU of 3fpm by Molmil](/molmil-images/mine/3fpm) | Crystal Structure of a Squarate Inhibitor bound to MAPKAP Kinase-2 | 分子名称: | 3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione, MAP kinase-activated protein kinase 2 | 著者 | Parris, K.D. | 登録日 | 2009-01-05 | 公開日 | 2009-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Identification and SAR of squarate inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2) Bioorg.Med.Chem., 17, 2009
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2NWT
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![BU of 2nwt by Molmil](/molmil-images/mine/2nwt) | NMR Structure of Protein UPF0165 protein AF_2212 from Archaeoglobus Fulgidus; Northeast Structural Genomics Consortium Target GR83 | 分子名称: | UPF0165 protein AF_2212 | 著者 | Singarapu, K.K, Sukumaran, D.K, Parish, D, Atreya, H.S, Liu, G, Eletsky, A, Chen, C.X, Jiang, M, Cunningham, K, Xiao, R, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-11-16 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of Protein Y2212_ARCFU from Archaeoglobus Fulgidus; Northeast Structural Genomics Consortium Target GR83 To be Published
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7U5B
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![BU of 7u5b by Molmil](/molmil-images/mine/7u5b) | |
8GI2
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![BU of 8gi2 by Molmil](/molmil-images/mine/8gi2) | Cryo-EM structure of Natrinema sp. J7-2 Type IV pilus | 分子名称: | Natrinema pilin, Orf10 | 著者 | Sonani, R.R, Kreutzberger, M.A.B, Liu, Y, Krupovic, M, Egelman, E.H. | 登録日 | 2023-03-13 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The evolution of archaeal flagellar filaments. Proc.Natl.Acad.Sci.USA, 120, 2023
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7DA4
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![BU of 7da4 by Molmil](/molmil-images/mine/7da4) | Cryo-EM structure of amyloid fibril formed by human RIPK3 | 分子名称: | Receptor-interacting serine/threonine-protein kinase 3 | 著者 | Zhao, K, Ma, Y.Y, Sun, Y.P, Li, D, Liu, C. | 登録日 | 2020-10-14 | 公開日 | 2021-04-28 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | 主引用文献 | The structure of a minimum amyloid fibril core formed by necroptosis-mediating RHIM of human RIPK3. Proc.Natl.Acad.Sci.USA, 118, 2021
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5EXH
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![BU of 5exh by Molmil](/molmil-images/mine/5exh) | |
8DUA
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![BU of 8dua by Molmil](/molmil-images/mine/8dua) | SIV E660.CR54 SOS-2P Env Trimer with ITS92.02 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Envelope glycoprotein gp41, ... | 著者 | Gorman, J, Kwong, P.D. | 登録日 | 2022-07-27 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (4.32 Å) | 主引用文献 | Cryo-EM structures of prefusion SIV envelope trimer. Nat.Struct.Mol.Biol., 29, 2022
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8DVD
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7DF1
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![BU of 7df1 by Molmil](/molmil-images/mine/7df1) | Crystal structure of human CD98 heavy chain extracellular domain in complex with S1-F4 scFv | 分子名称: | 4F2 cell-surface antigen heavy chain, IGL c2062_light_IGKV4-1_IGKJ5, S1-F4 VH | 著者 | Liu, X, Ding, J, Sui, J, Tian, X. | 登録日 | 2020-11-06 | 公開日 | 2022-12-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | 主引用文献 | An anti-CD98 antibody displaying pH-dependent Fc-mediated tumour-specific activity against multiple cancers in CD98-humanized mice. Nat Biomed Eng, 2022
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8EHI
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![BU of 8ehi by Molmil](/molmil-images/mine/8ehi) | Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (2) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-14 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EHF
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![BU of 8ehf by Molmil](/molmil-images/mine/8ehf) | Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (1) | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-14 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EG8
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![BU of 8eg8 by Molmil](/molmil-images/mine/8eg8) | Cryo-EM structure of consensus elemental paused elongation complex with a folded TL | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-12 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EHA
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![BU of 8eha by Molmil](/molmil-images/mine/8eha) | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (out) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-14 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EGB
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![BU of 8egb by Molmil](/molmil-images/mine/8egb) | Cryo-EM structure of consensus elemental paused elongation complex with an unfolded TL | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-12 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EG7
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![BU of 8eg7 by Molmil](/molmil-images/mine/8eg7) | Cryo-EM structure of pre-consensus elemental paused elongation complex | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-11 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EH8
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![BU of 8eh8 by Molmil](/molmil-images/mine/8eh8) | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (1) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-13 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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7JUP
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![BU of 7jup by Molmil](/molmil-images/mine/7jup) | Structure of human TRPA1 in complex with antagonist compound 21 | 分子名称: | 1-({3-[(3R,5R)-5-(4-fluorophenyl)oxolan-3-yl]-1,2,4-oxadiazol-5-yl}methyl)-7-methyl-1,7-dihydro-6H-purin-6-one, Transient receptor potential cation channel subfamily A member 1 | 著者 | Rohou, A, Rouge, L. | 登録日 | 2020-08-20 | 公開日 | 2021-03-31 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy. J.Med.Chem., 64, 2021
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8EH9
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![BU of 8eh9 by Molmil](/molmil-images/mine/8eh9) | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (2) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-13 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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7YOJ
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![BU of 7yoj by Molmil](/molmil-images/mine/7yoj) | Structure of CasPi with guide RNA and target DNA | 分子名称: | CasPi, DNA (30-MER), DNA (5'-D(P*CP*GP*GP*GP*AP*TP*GP*CP*CP*CP*AP*G)-3'), ... | 著者 | Li, C.P, Wang, J, Liu, J.J. | 登録日 | 2022-08-01 | 公開日 | 2023-02-15 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | The compact Cas pi (Cas12l) 'bracelet' provides a unique structural platform for DNA manipulation. Cell Res., 33, 2023
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