6LB0
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6KZ6
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![BU of 6kz6 by Molmil](/molmil-images/mine/6kz6) | Crystal structure of ASFV dUTPase | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R, MAGNESIUM ION | 著者 | Guo, Y, Chen, C, Li, G.B, Cao, L, Wang, C.W. | 登録日 | 2019-09-23 | 公開日 | 2019-11-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.187 Å) | 主引用文献 | Structural Insight into African Swine Fever Virus dUTPase Reveals a Novel Folding Pattern in the dUTPase Family. J.Virol., 94, 2020
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7DG4
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7DH9
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![BU of 7dh9 by Molmil](/molmil-images/mine/7dh9) | The co-crystal structure of DYRK2 with a small molecule inhibitor 7 | 分子名称: | Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridin-4-yl]methanol | 著者 | Wei, T, Xiao, J. | 登録日 | 2020-11-13 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
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7DHC
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![BU of 7dhc by Molmil](/molmil-images/mine/7dhc) | The co-crystal structure of DYRK2 with a small molecule inhibitor 10 | 分子名称: | 4-[bis(fluoranyl)methyl]-2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | 著者 | Wei, T, Xiao, J. | 登録日 | 2020-11-13 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.592 Å) | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
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7DHH
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![BU of 7dhh by Molmil](/molmil-images/mine/7dhh) | The co-crystal structure of DYRK2 with a small molecule inhibitor 19 | 分子名称: | Dual specificity tyrosine-phosphorylation-regulated kinase 2, [9-(azetidin-3-ylmethylsulfanyl)-2,7-dimethoxy-acridin-4-yl]methanol | 著者 | Wei, T, Xiao, J. | 登録日 | 2020-11-14 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.486 Å) | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
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7DHO
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![BU of 7dho by Molmil](/molmil-images/mine/7dho) | The co-crystal structure of DYRK2 with a small molecule inhibitor 14 | 分子名称: | 2-methoxy-9-(piperidin-4-ylmethylsulfanyl)-7-propan-2-yloxy-acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | 著者 | Wei, T, Xiao, J. | 登録日 | 2020-11-16 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
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7DHN
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![BU of 7dhn by Molmil](/molmil-images/mine/7dhn) | The co-crystal structure of DYRK2 with a small molecule inhibitor 20 | 分子名称: | 7-methoxy-2-methylsulfanyl-9-(piperidin-4-ylmethylsulfanyl)-[1,3]thiazolo[5,4-b]quinoline, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | 著者 | Wei, T, Xiao, J. | 登録日 | 2020-11-16 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
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7DHK
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![BU of 7dhk by Molmil](/molmil-images/mine/7dhk) | The co-crystal structure of DYRK2 with a small molecule inhibitor 13 | 分子名称: | 2-methoxy-7-phenylmethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | 著者 | Wei, T, Xiao, J. | 登録日 | 2020-11-16 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.341 Å) | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
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7DHV
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![BU of 7dhv by Molmil](/molmil-images/mine/7dhv) | The co-crystal structure of DYRK2 with a small molecule inhibitor 8 | 分子名称: | 2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine-4-carboxylic acid, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | 著者 | Wei, T, Xiao, J. | 登録日 | 2020-11-17 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.679 Å) | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
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7DJO
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![BU of 7djo by Molmil](/molmil-images/mine/7djo) | The co-crystal structure of DYRK2 with a small molecule inhibitor 17 | 分子名称: | Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol | 著者 | Wei, T, Xiao, J. | 登録日 | 2020-11-20 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
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7DL6
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![BU of 7dl6 by Molmil](/molmil-images/mine/7dl6) | The co-crystal structure of DYRK2 with a small molecule inhibitor 18 | 分子名称: | Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol | 著者 | Wei, T, Xiao, J. | 登録日 | 2020-11-26 | 公開日 | 2021-12-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.648 Å) | 主引用文献 | Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
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6UBI
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6UCE
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6UCF
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5W54
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8HWK
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![BU of 8hwk by Molmil](/molmil-images/mine/8hwk) | Limosilactobacillus reuteri N1 GtfB-maltohexaose | 分子名称: | CITRIC ACID, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | 著者 | Dong, J.J, Bai, Y.X. | 登録日 | 2022-12-30 | 公開日 | 2024-01-03 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Insights into the Structure-Function Relationship of GH70 GtfB alpha-Glucanotransferases from the Crystal Structure and Molecular Dynamic Simulation of a Newly Characterized Limosilactobacillus reuteri N1 GtfB Enzyme. J.Agric.Food Chem., 72, 2024
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8ILD
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![BU of 8ild by Molmil](/molmil-images/mine/8ild) | The crystal structure of native dGTP:DNApre-I:Pol X substrate ternary complex | 分子名称: | DNA (5'-D(*CP*AP*GP*GP*AP*TP*CP*CP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | 著者 | Qin, T, Chen, Y.Q, Gan, J.H, Huang, Z. | 登録日 | 2023-03-03 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom. Int J Mol Sci, 24, 2023
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8HW3
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![BU of 8hw3 by Molmil](/molmil-images/mine/8hw3) | Limosilactobacillus reuteri N1 GtfB-acarbose | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, GLYCEROL, SODIUM ION, ... | 著者 | Dong, J.J, Bai, Y.X. | 登録日 | 2022-12-28 | 公開日 | 2024-01-03 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Insights into the Structure-Function Relationship of GH70 GtfB alpha-Glucanotransferases from the Crystal Structure and Molecular Dynamic Simulation of a Newly Characterized Limosilactobacillus reuteri N1 GtfB Enzyme. J.Agric.Food Chem., 72, 2024
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8ILH
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![BU of 8ilh by Molmil](/molmil-images/mine/8ilh) | The crystal structure of dG(Se-Sp)-DNA:Pol X product binary complex | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOSELENOPHOSPHATE, DNA (5'-D(*CP*GP*GP*AP*TP*CP*C)-3'), MAGNESIUM ION, ... | 著者 | Qin, T, Gan, J.H, Huang, Z. | 登録日 | 2023-03-03 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom. Int J Mol Sci, 24, 2023
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8ILI
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![BU of 8ili by Molmil](/molmil-images/mine/8ili) | The crystal structure of dG(Se-Rp)-DNA:Pol X product binary complex | 分子名称: | DNA (5'-D(*CP*GP*GP*AP*TP*CP*CP*(7S8))-3'), MAGNESIUM ION, Repair DNA polymerase X, ... | 著者 | Qin, T, Gan, J.H, Huang, Z. | 登録日 | 2023-03-03 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom. Int J Mol Sci, 24, 2023
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6W50
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![BU of 6w50 by Molmil](/molmil-images/mine/6w50) | FACTOR XIA IN COMPLEX WITH THE INHIBITOR METHYL ((10R,14S)- 14-(4-(3-CHLORO-2,6-DIFLUOROPHENYL)-6-OXO-3,6-DIHYDRO- 1(2H)-PYRIDINYL)-10-METHYL-9-OXO-8,16- DIAZATRICYCLO[13.3.1.0~2,7~]NONADECA-1(19),2,4,6,15,17- HEXAEN-5-YL)CARBAMATE | 分子名称: | 1,2-ETHANEDIOL, Coagulation factor XI, SULFATE ION, ... | 著者 | Sheriff, S. | 登録日 | 2020-03-12 | 公開日 | 2020-06-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species. J.Med.Chem., 63, 2020
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1I5U
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![BU of 1i5u by Molmil](/molmil-images/mine/1i5u) | SOLUTION STRUCTURE OF CYTOCHROME B5 TRIPLE MUTANT (E48A/E56A/D60A) | 分子名称: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Qian, C, Yao, Y, Tang, W, Wang, J, Zhongxian, H. | 登録日 | 2001-02-28 | 公開日 | 2001-03-21 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Effects of charged amino-acid mutation on the solution structure of cytochrome b(5) and binding between cytochrome b(5) and cytochrome c. Protein Sci., 10, 2001
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7YTD
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![BU of 7ytd by Molmil](/molmil-images/mine/7ytd) | Cryo-EM structure of four human FcmR bound to IgM-Fc/J | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | 著者 | Li, Y, Shen, H, Xiao, J. | 登録日 | 2022-08-14 | 公開日 | 2023-02-01 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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7YSG
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![BU of 7ysg by Molmil](/molmil-images/mine/7ysg) | Cryo-EM structure of human FcmR bound to sIgM | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | 著者 | Li, Y, Shen, H, Xiao, J. | 登録日 | 2022-08-12 | 公開日 | 2023-02-01 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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