6REN
 
 | | Crystal structure of 3fPizza6-SH with Zn2+ | | 分子名称: | 3fPizza6-SH, GLYCEROL, ISOPROPYL ALCOHOL, ... | | 著者 | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | | 登録日 | 2019-04-12 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Artificial beta-propeller protein-based hydrolases.
Chem.Commun.(Camb.), 55, 2019
|
|
6BMT
 | |
8ER6
 | | FKBP12-FRB in Complex with Compound 11 | | 分子名称: | (3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5,9,27-trihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone, 1,2-ETHANEDIOL, Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | 著者 | Tomlinson, A.C.A, Yano, J.K. | | 登録日 | 2022-10-11 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors.
J.Med.Chem., 66, 2023
|
|
8ER7
 | | FKBP12-FRB in Complex with Compound 12 | | 分子名称: | (3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-5,10,21-trimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | 著者 | Tomlinson, A.C.A, Yano, J.K. | | 登録日 | 2022-10-11 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors.
J.Med.Chem., 66, 2023
|
|
6REH
 | | Crystal structure of Pizza6-S with Cu2+ | | 分子名称: | COPPER (II) ION, GLYCEROL, Pizza6-S, ... | | 著者 | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | | 登録日 | 2019-04-12 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Artificial beta-propeller protein-based hydrolases.
Chem.Commun.(Camb.), 55, 2019
|
|
6REJ
 | | Crystal structure of Pizza6-SH with Zn2+ | | 分子名称: | Pizza6-SH, SULFATE ION, ZINC ION | | 著者 | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | | 登録日 | 2019-04-12 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Artificial beta-propeller protein-based hydrolases.
Chem.Commun.(Camb.), 55, 2019
|
|
6UW6
 | |
6UW9
 | |
8CXJ
 | |
6VDA
 | |
6CA4
 | |
6UW8
 | |
6UZY
 | | Cryo-EM structure of Xenopus tropicalis pannexin 1 | | 分子名称: | HEXADECANE, Pannexin, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Deng, Z, He, Z, Yuan, P. | | 登録日 | 2019-11-15 | | 公開日 | 2020-04-01 | | 最終更新日 | 2020-04-22 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Cryo-EM structures of the ATP release channel pannexin 1.
Nat.Struct.Mol.Biol., 27, 2020
|
|
6RTN
 | | Crystal structure of OXA-10 with VNRX-5133 | | 分子名称: | (3~{R})-3-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid, Beta-lactamase OXA-10, CHLORIDE ION | | 著者 | Brem, J, Schofield, C. | | 登録日 | 2019-05-24 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-beta-Lactamases.
J.Med.Chem., 62, 2019
|
|
8F35
 | | Apo ELIC in spMSP1D1 nanodiscs with 2:1:1 POPC:POPE:POPG | | 分子名称: | Erwinia chrysanthemi ligand-gated ion channel | | 著者 | Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L. | | 登録日 | 2022-11-09 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
|
|
8F34
 | | ELIC with Propylamine in spMSP1D1 nanodiscs with 2:1:1 POPC:POPE:POPG | | 分子名称: | 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel | | 著者 | Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L. | | 登録日 | 2022-11-09 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
|
|
8F33
 | | ELIC with Propylamine in saposin nanodiscs with 2:1:1 POPC:POPE:POPG | | 分子名称: | 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel | | 著者 | Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L. | | 登録日 | 2022-11-09 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
|
|
8F32
 | | ELIC with Propylamine in SMA nanodiscs with 2:1:1 POPC:POPE:POPG | | 分子名称: | 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel | | 著者 | Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L. | | 登録日 | 2022-11-09 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
|
|
6VD8
 | |
6V3P
 | |
6V6D
 | |
6AZP
 | |
6VD9
 | |
8FPT
 | | STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE | | 分子名称: | Alpha-synuclein | | 著者 | Barclay, A.M, Dhavale, D.D, Borcik, C.G, Rau, M.J, Basore, K, Milchberg, M.H, Warmuth, O.A, Kotzbauer, P.T, Rienstra, C.M, Schwieters, C.D. | | 登録日 | 2023-01-05 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue.
Biorxiv, 2023
|
|
8F7C
 | |
