1XI4
 
 | | Clathrin D6 Coat | | 分子名称: | Clathrin heavy chain, Clathrin light chain A | | 著者 | Fotin, A, Cheng, Y, Sliz, P, Grigorieff, N, Harrison, S.C, Kirchhausen, T, Walz, T. | | 登録日 | 2004-09-21 | | 公開日 | 2004-11-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | Molecular model for a complete clathrin lattice from electron cryomicroscopy
Nature, 432, 2004
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6DJP
 | | Integrin alpha-v beta-8 in complex with the Fabs 8B8 and 68 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 68 heavy chain Fab, ... | | 著者 | Cormier, A, Campbell, M.G, Nishimura, S.L, Cheng, Y. | | 登録日 | 2018-05-25 | | 公開日 | 2018-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Cryo-EM structure of the alpha v beta 8 integrin reveals a mechanism for stabilizing integrin extension.
Nat. Struct. Mol. Biol., 25, 2018
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6E1M
 | | Structure of AtTPC1(DDE) reconstituted in saposin A | | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ... | | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | | 登録日 | 2018-07-10 | | 公開日 | 2018-09-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E1P
 | | Structure of AtTPC1(DDE) in state 2 | | 分子名称: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1 | | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | | 登録日 | 2018-07-10 | | 公開日 | 2018-09-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E1N
 | | Structure of AtTPC1(DDE) in state 1 | | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ... | | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | | 登録日 | 2018-07-10 | | 公開日 | 2018-09-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E1K
 | | Structure of AtTPC1(DDE) reconstituted in saposin A with cat06 Fab | | 分子名称: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ... | | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | | 登録日 | 2018-07-10 | | 公開日 | 2018-09-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3IPM
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4KWE
 | | GDP-bound, double-stranded, curved FtsZ protofilament structure | | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Li, Y, Hsin, J, Zhao, L, Cheng, Y, Shang, W, Huang, K.C, Wang, H.W, Ye, S. | | 登録日 | 2013-05-23 | | 公開日 | 2013-07-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | FtsZ protofilaments use a hinge-opening mechanism for constrictive force generation
Science, 341, 2013
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3J9P
 | | Structure of the TRPA1 ion channel determined by electron cryo-microscopy | | 分子名称: | Maltose-binding periplasmic protein, Transient receptor potential cation channel subfamily A member 1 chimera | | 著者 | Paulsen, C.E, Armache, J.-P, Gao, Y, Cheng, Y, Julius, D. | | 登録日 | 2015-02-14 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | | 主引用文献 | Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature, 520, 2015
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4JZA
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2B6P
 | | X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state | | 分子名称: | Lens fiber major intrinsic protein | | 著者 | Gonen, T, Cheng, Y, Sliz, P, Hiroaki, Y, Fujiyoshi, Y, Harrison, S.C, Walz, T. | | 登録日 | 2005-10-03 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
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2B6O
 | | Electron crystallographic structure of lens Aquaporin-0 (AQP0) (lens MIP) at 1.9A resolution, in a closed pore state | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Lens fiber major intrinsic protein | | 著者 | Gonen, T, Cheng, Y, Sliz, P, Hiroaki, Y, Fujiyoshi, Y, Harrison, S.C, Walz, T. | | 登録日 | 2005-10-03 | | 公開日 | 2005-12-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.9 Å) | | 主引用文献 | Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
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7MZ5
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7MZB
 | | Cryo-EM structure of minimal TRPV1 with 3 bound RTX and 1 perturbed PI | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2021-05-24 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7MZ6
 | | Cryo-EM structure of minimal TRPV1 with 1 perturbed PI | | 分子名称: | (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2021-05-24 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7MZC
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7MZA
 | | Cryo-EM structure of minimal TRPV1 with 2 bound RTX in adjacent pockets | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2021-05-24 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7MZ9
 | | Cryo-EM structure of minimal TRPV1 with 1 partially bound RTX | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2021-05-24 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7MZ7
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7MZE
 | | Cryo-EM structure of minimal TRPV1 with 2 bound RTX in opposite pockets | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2021-05-24 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7MZD
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8CXO
 | | Cryo-EM structure of the unliganded mSMO-PGS2 in a lipidic environment | | 分子名称: | CHOLESTEROL, Smoothened homolog, GlgA glycogen synthase chimera | | 著者 | Zhang, K, Wu, H, Hoppe, N, Manglik, A, Cheng, Y. | | 登録日 | 2022-05-22 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Fusion protein strategies for cryo-EM study of G protein-coupled receptors.
Nat Commun, 13, 2022
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3IYV
 | | Clathrin D6 coat as full-length Triskelions | | 分子名称: | Clathrin heavy chain, Clathrin light chain A | | 著者 | Johnson, G.T, Fotin, A, Cheng, Y, Sliz, P, Grigorieff, N, Harrison, S.C, Kirchhausen, T, Walz, T. | | 登録日 | 2010-06-17 | | 公開日 | 2010-07-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | Molecular model for a complete clathrin lattice from electron cryomicroscopy.
Nature, 432, 2004
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3J9I
 | | Thermoplasma acidophilum 20S proteasome | | 分子名称: | Proteasome subunit alpha, Proteasome subunit beta | | 著者 | Li, X, Mooney, P, Zheng, S, Booth, C, Braunfeld, M.B, Gubbens, S, Agard, D.A, Cheng, Y. | | 登録日 | 2015-02-02 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.
Nat.Methods, 10, 2013
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6O6R
 | | Structure of the TRPM8 cold receptor by single particle electron cryo-microscopy, AMTB-bound state | | 分子名称: | (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate, CHOLESTEROL HEMISUCCINATE, N-(3-aminopropyl)-2-[(3-methylphenyl)methoxy]-N-[(thiophen-2-yl)methyl]benzamide, ... | | 著者 | Diver, M.M, Cheng, Y, Julius, D. | | 登録日 | 2019-03-07 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into TRPM8 inhibition and desensitization.
Science, 365, 2019
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