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7F66
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eIF2B-SFSV NSs-1-eIF2
分子名称: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ...
著者Kashiwagi, K, Ito, T.
登録日2021-06-24
公開日2021-12-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
7F64
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BU of 7f64 by Molmil
eIF2B-SFSV NSs
分子名称: Non-structural protein NS-S, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ...
著者Kashiwagi, K, Ito, T.
登録日2021-06-24
公開日2021-12-08
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
7LUI
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BU of 7lui by Molmil
Crystal structure of Vibrio cholerae DsbA in complex with bile salt taurocholate
分子名称: GLYCEROL, TAUROCHOLIC ACID, Thiol:disulfide interchange protein DsbA
著者Wang, G, Heras, B.
登録日2021-02-22
公開日2021-12-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials.
Chemmedchem, 17, 2022
7LSM
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BU of 7lsm by Molmil
Crystal structure of E.coli DsbA in complex with bile salt taurocholate
分子名称: DI(HYDROXYETHYL)ETHER, TAUROCHOLIC ACID, Thiol:disulfide interchange protein DsbA
著者Wang, G, Heras, B.
登録日2021-02-18
公開日2021-12-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.786 Å)
主引用文献Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials.
Chemmedchem, 17, 2022
7FH2
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BU of 7fh2 by Molmil
Crystal structure of the first bromodomain of BRD4 in complex with 16D10
分子名称: Bromodomain-containing protein 4, CHLORIDE ION, N-[2-[2-[(E)-3-(2,5-dimethoxyphenyl)prop-2-enoyl]-4,5-dimethoxy-phenyl]ethyl]ethanamide
著者Yokoyama, T, Hirasawa, N.
登録日2021-07-29
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.492 Å)
主引用文献A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins.
Biochem Pharmacol, 194, 2021
7MCA
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BU of 7mca by Molmil
Structure of the S. cerevisiae origin recognition complex bound to the replication initiator Cdc6 and the ARS1 origin DNA.
分子名称: Cell division control protein 6, DNA (85-MER), MAGNESIUM ION, ...
著者Feng, X, Li, H.
登録日2021-04-01
公開日2021-06-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Nat Commun, 12, 2021
1TEZ
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BU of 1tez by Molmil
COMPLEX BETWEEN DNA AND THE DNA PHOTOLYASE FROM ANACYSTIS NIDULANS
分子名称: 5'-D(*AP*TP*CP*GP*GP*CP*T*(TCP)P*CP*GP*C)-3', 5'-D(*TP*CP*GP*C)-3', 5'-D(P*CP*GP*AP*AP*GP*CP*CP*GP*A)-3', ...
著者Essen, L.-O, Carell, T, Mees, A, Klar, T.
登録日2004-05-26
公開日2004-12-14
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a photolyase bound to a CPD-like DNA lesion after in situ repair
Science, 306, 2004
3S7T
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BU of 3s7t by Molmil
Crystal structure of SeMet B. licheniformis CDPS YvmC-Blic
分子名称: Putative uncharacterized protein yvmC
著者Bonnefond, L, Ishitani, R, Nureki, O.
登録日2011-05-26
公開日2011-06-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.808 Å)
主引用文献Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog.
Proc.Natl.Acad.Sci.USA, 108, 2011
3UMX
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BU of 3umx by Molmil
Crystal structure of Pim1 kinase in complex with inhibitor (Z)-2-[(1H-indol-3-yl)methylene]-7-(azepan-1-ylmethyl)-6-hydroxybenzofuran-3(2H)-one
分子名称: (2Z)-7-(azepan-1-ylmethyl)-6-hydroxy-2-(1H-indol-3-ylmethylidene)-1-benzofuran-3(2H)-one, Proto-oncogene serine/threonine-protein kinase pim-1, SULFATE ION
著者Parker, L.J, Handa, N, Yokoyama, S.
登録日2011-11-15
公開日2012-08-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Flexibility of the P-loop of Pim-1 kinase: observation of a novel conformation induced by interaction with an inhibitor
Acta Crystallogr.,Sect.F, 68, 2012
3V3T
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BU of 3v3t by Molmil
Crystal structure of Clostridium botulinum phage c-st TubZ
分子名称: Cell division GTPase FtsZ, diverged
著者Oliva, M.A.
登録日2011-12-14
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Tubulin homolog TubZ in a phage-encoded partition system.
Proc.Natl.Acad.Sci.USA, 109, 2012
6IF5
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BU of 6if5 by Molmil
Crystal structure of monkey TLR7 in complex with 2',3'-cGMP (Guanosine 2',3'-cyclic phosphate)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GUANOSINE-5'-PHOSPHATE-2',3'-CYCLIC PHOSPHATE, ...
著者Zhang, Z, Ohto, U, Shimizu, T.
登録日2018-09-18
公開日2019-01-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands.
Cell Rep, 25, 2018
3VXK
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BU of 3vxk by Molmil
Crystal structure of OsD14
分子名称: Dwarf 88 esterase
著者Xue, Y.-L, Miyakawa, T, Hou, F, Qin, H.-M, Tanokura, M.
登録日2012-09-18
公開日2013-09-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular mechanism of strigolactone perception by DWARF14
Nat Commun, 4, 2013
376D
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BU of 376d by Molmil
A ZIPPER-LIKE DNA DUPLEX D(GCGAAAGCT)
分子名称: COBALT HEXAMMINE(III), DNA (5'-D(*GP*(CBR)P*GP*AP*AP*AP*GP*CP*T)-3')
著者Cruse, W.B.T, Shepard, W, Prange, T, delalFortelle, E, Fourme, R.
登録日1998-01-22
公開日1999-10-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A zipper-like duplex in DNA: the crystal structure of d(GCGAAAGCT) at 2.1 A resolution.
Structure, 6, 1998
3WF6
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BU of 3wf6 by Molmil
Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine
分子名称: 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.031 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
6JCK
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BU of 6jck by Molmil
Complex structure of Axin-DIX and Dvl2-DIX
分子名称: Axin-1, Segment polarity protein dishevelled homolog DVL-2
著者Yamanishi, K, Shibata, N.
登録日2019-01-29
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献A direct heterotypic interaction between the DIX domains of Dishevelled and Axin mediates signaling to beta-catenin.
Sci.Signal., 12, 2019
3WNZ
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BU of 3wnz by Molmil
Crystal structure of Bacillus subtilis YwfE, an L-amino acid ligase, with bound ADP-Mg-Pi
分子名称: ADENOSINE-5'-DIPHOSPHATE, Alanine-anticapsin ligase BacD, MAGNESIUM ION, ...
著者Tsuda, T, Kojima, S.
登録日2013-12-19
公開日2014-05-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Single Mutation Alters the Substrate Specificity of l-Amino Acid Ligase
Biochemistry, 53, 2014
3WE4
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BU of 3we4 by Molmil
Crystal structure of S6K1 kinase domain in complex with a pyrimidine derivative PF-4708671 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole
分子名称: 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, Ribosomal protein S6 kinase beta-1, ZINC ION
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-06-29
公開日2014-08-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.995 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WF7
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BU of 3wf7 by Molmil
Crystal structure of S6K1 kinase domain in complex with a purine derivative 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide
分子名称: 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WIO
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BU of 3wio by Molmil
Crystal structure of OSD14 in complex with hydroxy D-ring
分子名称: (5R)-5-hydroxy-3-methylfuran-2(5H)-one, Probable strigolactone esterase D14
著者Xue, Y.-L, Miyakawa, T, Hou, F, Qin, H.-M, Tanokura, M.
登録日2013-09-22
公開日2013-10-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular mechanism of strigolactone perception by DWARF14
Nat Commun, 4, 2013
3WO0
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BU of 3wo0 by Molmil
Crystal structure of Bacillus subtilis YwfE, an L-amino acid ligase, with bound ADP-Mg-Ala
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALANINE, Alanine-anticapsin ligase BacD, ...
著者Tsuda, T, Kojima, S.
登録日2013-12-19
公開日2014-05-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Single Mutation Alters the Substrate Specificity of l-Amino Acid Ligase
Biochemistry, 53, 2014
3WF5
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BU of 3wf5 by Molmil
Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
分子名称: 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WO1
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Crystal structure of Trp332Ala mutant YwfE, an L-amino acid ligase, with bound ADP-Mg-Ala
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALANINE, Alanine-anticapsin ligase BacD, ...
著者Tsuda, T, Kojima, S.
登録日2013-12-19
公開日2014-05-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Single Mutation Alters the Substrate Specificity of l-Amino Acid Ligase
Biochemistry, 53, 2014
3WF8
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BU of 3wf8 by Molmil
Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate
分子名称: 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WF9
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Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl-2-methyl-1,2,3,4-tetrahydroacridine-9-carboxylate
分子名称: (2S)-1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl (2S)-2-methyl-1,2,3,4-tetrahydroacridine-9-carboxylate, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.035 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3X2O
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BU of 3x2o by Molmil
Neutron and X-ray joint refined structure of PcCel45A apo form at 298K.
分子名称: Endoglucanase V-like protein
著者Nakamura, A, Ishida, T, Kusaka, K, Yamada, T, Tanaka, I, Niimura, N, Samejima, M, Igarashi, K.
登録日2014-12-22
公開日2015-10-07
最終更新日2019-12-18
実験手法NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION
主引用文献"Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015

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