3TH9
| Crystal Structure of HIV-1 Protease Mutant Q7K V32I L63I with a cyclic sulfonamide inhibitor | 分子名称: | Gag-Pol polyprotein, tert-butyl {(2S,3R)-4-[(4S)-7-fluoro-4-methyl-1,1-dioxido-4,5-dihydro-1,2-benzothiazepin-2(3H)-yl]-3-hydroxy-1-phenylbutan-2-yl}carbamate | 著者 | Orth, P. | 登録日 | 2011-08-18 | 公開日 | 2011-09-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Design, Synthesis, and X-ray Crystallographic Analysis of a Novel Class of HIV-1 Protease Inhibitors. J.Med.Chem., 54, 2011
|
|
8IO9
| |
8IOA
| |
8IO8
| |
8IO7
| |
8IO6
| |
8IOE
| |
8XID
| |
8K3Y
| The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Zhang, K, Chang, C.I. | 登録日 | 2023-07-17 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (4.42 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
|
|
4MC9
| HIV protease in complex with AA74 | 分子名称: | (3S)-tetrahydrofuran-3-yl {(2S,3R)-4-[(4R)-7-fluoro-1,1-dioxido-4-(propan-2-yl)-4,5-dihydro-1,2-benzothiazepin-2(3H)-yl]-3-hydroxy-1-phenylbutan-2-yl}carbamate, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Ganguly, A.K, Alluri, S.S, Wang, C, Antropow, A, White, A, Caroccia, D, Biswas, D, Kang, E, Zhang, L, Carroll, S.S, Burlein, C, Munshi, V, Orth, P, Strickland, C. | 登録日 | 2013-08-21 | 公開日 | 2014-04-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Structural Optimization of Cyclic Sulfonamide based Novel HIV-1 Protease Inhibitors to Pico Molar Affinities guided by X-ray Crystallographic Analysis Tetrahedron, 2014
|
|
7W6M
| Cryo-EM map of PEDV (Pintung 52) S protein with all three protomers in the D0-down conformation determined in situ on intact viral particles. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | 登録日 | 2021-12-02 | 公開日 | 2022-08-03 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM. Nat Commun, 13, 2022
|
|
7W73
| Cryo-EM map of PEDV S protein with one protomer in the D0-up conformation while the other two in the D0-down conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | 登録日 | 2021-12-03 | 公開日 | 2022-08-03 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | 主引用文献 | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM. Nat Commun, 13, 2022
|
|
7Y6T
| Cryo-EM map of IPEC-J2 cell-derived PEDV PT52 S protein one D0-down and two D0-up | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | 登録日 | 2022-06-21 | 公開日 | 2022-08-03 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM. Nat Commun, 13, 2022
|
|
7Y6U
| Symmetry-expanded and locally refined protomer structure of IPEC-J2 cell-derived PEDV PT52 S with a CTD-close conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | 登録日 | 2022-06-21 | 公開日 | 2022-08-03 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM. Nat Commun, 13, 2022
|
|
7Y6V
| Symmetry-expanded and locally refined protomer structure of IPEC-J2 cell-derived PEDV PT52 S with a CTD-open conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | 登録日 | 2022-06-21 | 公開日 | 2022-08-03 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM. Nat Commun, 13, 2022
|
|
7Y6S
| Cryo-EM map of IPEC-J2 cell-derived PEDV PT52 S protein with three D0-up | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | 登録日 | 2022-06-21 | 公開日 | 2022-08-03 | 最終更新日 | 2024-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM. Nat Commun, 13, 2022
|
|
4OM5
| |
4OM4
| |
6LUS
| Crystal structure of the Mengla Virus VP30 C-terminal domain | 分子名称: | Minor nucleoprotein VP30 | 著者 | Dong, S.S, Wen, K.N, Chu, H.G, Wang, C.H, Qin, X.C. | 登録日 | 2020-01-30 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of the Mengla virus VP30 C-terminal domain. Biochem.Biophys.Res.Commun., 525, 2020
|
|
8JBQ
| |
7WCV
| Co-crystal structure of FTO bound to 6e | 分子名称: | 2-OXOGLUTARIC ACID, 2-[[2,6-bis(chloranyl)-4-pyridin-4-yl-phenyl]amino]benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ... | 著者 | Yang, C.-G, Gan, J.H. | 登録日 | 2021-12-20 | 公開日 | 2022-07-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors. J.Med.Chem., 65, 2022
|
|
7XPJ
| crystal structure of rice ASI1 BAH domain | 分子名称: | BAH domain-containing protein | 著者 | Yuan, J, Du, J. | 登録日 | 2022-05-04 | 公開日 | 2023-01-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Molecular basis of locus-specific H3K9 methylation catalyzed by SUVH6 in plants. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
7XPK
| |