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5V39
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BU of 5v39 by Molmil
Crystal structure of human vitamin D receptor ligand binding domain in complex with a VDRM
分子名称: 5-(3-{4-[(2S)-2-hydroxy-3,3-dimethylbutoxy]-3-methylphenyl}pentan-3-yl)-3-methyl-N-(1H-tetrazol-5-yl)thiophene-2-carboxamide, Vitamin D3 receptor
著者Wang, Y, Pelletier, L.
登録日2017-03-06
公開日2018-03-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions.
Nat Commun, 8, 2017
5NNE
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BU of 5nne by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated TOP2A peptide (K1201ac/K1204ac)
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, GKA(ALY)GK(ALY)TQMY
著者Filippakopoulos, P, Picaud, S, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C.
登録日2017-04-08
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Mol. Cell, 73, 2019
5NNC
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BU of 5nnc by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H3K9ac/K14ac)
分子名称: Bromodomain-containing protein 4, Histone H3
著者Filippakopoulos, P, Picaud, S, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C.
登録日2017-04-08
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Mol. Cell, 73, 2019
5NNG
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BU of 5nng by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated SRPK1 peptide (K585ac)
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, VAG(ALY)YS(ALY)EFFY
著者Filippakopoulos, P, Picaud, S, Newman, J, Sorrell, F, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Structural Genomics Consortium (SGC)
登録日2017-04-08
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Mol. Cell, 73, 2019
5NNF
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BU of 5nnf by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated BAZ1B peptide (K221ac)
分子名称: Bromodomain-containing protein 4, FLPH(ALY)YDVKL
著者Filippakopoulos, P, Picaud, S, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C.
登録日2017-04-08
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Mol. Cell, 73, 2019
5NND
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BU of 5nnd by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H3K9ac/K14ac)
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, Histone H3
著者Filippakopoulos, P, Picaud, S, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C.
登録日2017-04-08
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Mol. Cell, 73, 2019
5OI9
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BU of 5oi9 by Molmil
Trichoplax adhaerens STIL N-terminal domain
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Putative uncharacterized protein
著者van Breugel, M.
登録日2017-07-18
公開日2018-04-18
最終更新日2018-05-09
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
5OI7
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BU of 5oi7 by Molmil
Human CEP85 - coiled coil domain 4
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Centrosomal protein of 85 kDa
著者van Breugel, M.
登録日2017-07-18
公開日2018-04-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
5OID
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BU of 5oid by Molmil
Complex Trichoplax STIL-NTD:human CEP85 coiled coil domain 4
分子名称: Centrosomal protein of 85 kDa, Putative uncharacterized protein
著者van Breugel, M.
登録日2017-07-18
公開日2018-04-18
最終更新日2018-05-09
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
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