7BS4
| Bovine Pancreatic Trypsin with 5-Methoxytryptamine (Cryo) | 分子名称: | 2-(5-methoxy-1H-indol-3-yl)ethanamine, CALCIUM ION, Cationic trypsin, ... | 著者 | Maeki, M, Ito, S, Takeda, R, Funakubo, T, Ueno, G, Ishida, A, Tani, H, Yamamoto, M, Tokeshi, M. | 登録日 | 2020-03-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis. Chem Sci, 11, 2020
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7BRV
| Bovine Pancreatic Trypsin with 4-Bromobenzamidine (Room Temperature) | 分子名称: | 4-bromanylbenzenecarboximidamide, CALCIUM ION, Cationic trypsin, ... | 著者 | Takeda, R, Ito, S, Maeki, M, Funakubo, T, Ueno, G, Ishida, A, Tani, H, Yamamoto, M, Tokeshi, M. | 登録日 | 2020-03-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis. Chem Sci, 11, 2020
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7BRZ
| Bovine Pancreatic Trypsin with 2-Methyltryptamine (Room Temperature) | 分子名称: | 2-(2-methyl-1H-indol-3-yl)ethanamine, CALCIUM ION, Cationic trypsin, ... | 著者 | Maeki, M, Ito, S, Takeda, R, Funakubo, T, Ueno, G, Ishida, A, Tani, H, Yamamoto, M, Tokeshi, M. | 登録日 | 2020-03-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis. Chem Sci, 11, 2020
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7BS7
| Bovine Pancreatic Trypsin with aniline (Cryo) | 分子名称: | ANILINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Maeki, M, Ito, S, Takeda, R, Funakubo, T, Ueno, G, Ishida, A, Tani, H, Yamamoto, M, Tokeshi, M. | 登録日 | 2020-03-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis. Chem Sci, 11, 2020
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7BS6
| Bovine Pancreatic Trypsin with 2-Methyltryptamine (Cryo) | 分子名称: | 2-(2-methyl-1H-indol-3-yl)ethanamine, CALCIUM ION, Cationic trypsin, ... | 著者 | Maeki, M, Ito, S, Takeda, R, Funakubo, T, Ueno, G, Ishida, A, Tani, H, Yamamoto, M, Tokeshi, M. | 登録日 | 2020-03-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis. Chem Sci, 11, 2020
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7BS3
| Bovine Pancreatic Trypsin with 4-Bromo-benzamidine (Cryo) | 分子名称: | 4-bromanylbenzenecarboximidamide, CALCIUM ION, Cationic trypsin, ... | 著者 | Maeki, M, Ito, S, Takeda, R, Funakubo, T, Ueno, G, Ishida, A, Tani, H, Yamamoto, M, Tokeshi, M. | 登録日 | 2020-03-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis. Chem Sci, 11, 2020
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1AN9
| D-AMINO ACID OXIDASE COMPLEX WITH O-AMINOBENZOATE | 分子名称: | 2-AMINOBENZOIC ACID, D-AMINO ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Miura, R, Setoyama, C, Nishina, Y, Shiga, K, Mizutani, H, Miyahara, I, Hirotsu, K. | 登録日 | 1997-06-28 | 公開日 | 1997-11-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and mechanistic studies on D-amino acid oxidase x substrate complex: implications of the crystal structure of enzyme x substrate analog complex. J.Biochem.(Tokyo), 122, 1997
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5E8D
| Crystal structure of human epiregulin in complex with the Fab fragment of murine monoclonal antibody 9E5 | 分子名称: | CHLORIDE ION, GLYCEROL, Proepiregulin, ... | 著者 | Kado, Y, Mizohata, E, Nagatoishi, S, Iijima, M, Shinoda, K, Miyafusa, T, Nakayama, T, Yoshizumi, T, Sugiyama, A, Kawamura, T, Lee, Y.H, Matsumura, H, Doi, H, Fujitani, H, Kodama, T, Shibasaki, Y, Tsumoto, K, Inoue, T. | 登録日 | 2015-10-14 | 公開日 | 2015-12-09 | 最終更新日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES J.Biol.Chem., 291, 2016
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8J12
| Cryo-EM structure of the AsCas12f-sgRNA-target DNA ternary complex | 分子名称: | DNA (38-MER), MAGNESIUM ION, RNA (247-MER), ... | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | 登録日 | 2023-04-12 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Minimal and most efficient genome editing Cas enzyme To Be Published
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8J1J
| Cryo-EM structure of the AsCas12f-YHAM-sgRNAS3-5v7-target DNA | 分子名称: | DNA (38-MER), MAGNESIUM ION, RNA (118-MER), ... | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | 登録日 | 2023-04-13 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | Minimal and most efficient genome editing Cas enzyme To Be Published
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8J3R
| Cryo-EM structure of the AsCas12f-HKRA-sgRNAS3-5v7-target DNA | 分子名称: | DNA (37-MER), DNA (38-MER), MAGNESIUM ION, ... | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | 登録日 | 2023-04-18 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Minimal and most efficient genome editing Cas enzyme To Be Published
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1IWQ
| Crystal Structure of MARCKS calmodulin binding domain peptide complexed with Ca2+/Calmodulin | 分子名称: | CALCIUM ION, CALMODULIN, MARCKS | 著者 | Yamauchi, E, Nakatsu, T, Matsubara, M, Kato, H, Taniguchi, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-05-31 | 公開日 | 2003-03-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca(2+)-calmodulin NAT.STRUCT.BIOL., 10, 2003
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5AZ2
| Crystal structure of the Fab fragment of 9E5, a murine monoclonal antibody specific for human epiregulin | 分子名称: | anti-human epiregulin antibody 9E5 Fab heavy chain, anti-human epiregulin antibody 9E5 Fab light chain | 著者 | Kado, Y, Mizohata, E, Nagatoishi, S, Iijima, M, Shinoda, K, Miyafusa, T, Nakayama, T, Yoshizumi, T, Sugiyama, A, Kawamura, T, Lee, Y.H, Matsumura, H, Doi, H, Fujitani, H, Kodama, T, Shibasaki, Y, Tsumoto, K, Inoue, T. | 登録日 | 2015-09-16 | 公開日 | 2015-12-09 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (1.603 Å) | 主引用文献 | Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES J.Biol.Chem., 291, 2016
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1L7Z
| Crystal structure of Ca2+/Calmodulin complexed with myristoylated CAP-23/NAP-22 peptide | 分子名称: | CALCIUM ION, CALMODULIN, CAP-23/NAP-22, ... | 著者 | Matsubara, M, Nakatsu, T, Yamauchi, E, Kato, H, Taniguchi, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-03-18 | 公開日 | 2003-09-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a myristoylated CAP-23/NAP-22 N-terminal domain complexed with Ca2+/calmodulin EMBO J., 23, 2004
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5GKS
| Crystal structure of SLE patient-derived anti-DNA antibody | 分子名称: | IgG2, Fab (heavy chain), PHOSPHATE ION, ... | 著者 | Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J. | 登録日 | 2016-07-05 | 公開日 | 2017-07-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus Sci Rep, 7, 2017
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5GKR
| Crystal structure of SLE patient-derived anti-DNA antibody in complex with oligonucleotide | 分子名称: | DNA (5'-D(P*TP*TP*TP*T)-3'), IgG2, Fab (heavy chain), ... | 著者 | Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J. | 登録日 | 2016-07-05 | 公開日 | 2017-07-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus Sci Rep, 7, 2017
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1WSV
| Crystal Structure of Human T-protein of Glycine Cleavage System | 分子名称: | Aminomethyltransferase, N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, SULFATE ION | 著者 | Okamura-Ikeda, K, Hosaka, H, Yoshimura, M, Yamashita, E, Toma, S, Nakagawa, A, Fujiwara, K, Motokawa, Y, Taniguchi, H. | 登録日 | 2004-11-11 | 公開日 | 2005-08-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Human T-protein of Glycine Cleavage System at 2.0A Resolution and its Implication for Understanding Non-ketotic Hyperglycinemia J.Mol.Biol., 351, 2005
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1WSR
| Crystal Structure of Human T-protein of Glycine Cleavage System | 分子名称: | Aminomethyltransferase, SULFATE ION | 著者 | Okamura-Ikeda, K, Hosaka, H, Yoshimura, M, Yamashita, E, Toma, S, Nakagawa, A, Fujiwara, K, Motokawa, Y, Taniguchi, H. | 登録日 | 2004-11-10 | 公開日 | 2005-08-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Human T-protein of Glycine Cleavage System at 2.0A Resolution and its Implication for Understanding Non-ketotic Hyperglycinemia J.Mol.Biol., 351, 2005
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3W82
| Human alpha-L-iduronidase in complex with iduronic acid | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-L-iduronidase, ... | 著者 | Maita, N, Tsukimura, T, Taniguchi, T, Saito, S, Ohno, K, Taniguchi, H, Sakuraba, H. | 登録日 | 2013-03-11 | 公開日 | 2013-08-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Human alpha-L-iduronidase uses its own N-glycan as a substrate-binding and catalytic module Proc.Natl.Acad.Sci.USA, 110, 2013
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3W81
| Human alpha-l-iduronidase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-L-iduronidase, ... | 著者 | Maita, N, Tsukimura, T, Taniguchi, T, Saito, S, Ohno, K, Taniguchi, H, Sakuraba, H. | 登録日 | 2013-03-11 | 公開日 | 2013-08-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Human alpha-L-iduronidase uses its own N-glycan as a substrate-binding and catalytic module Proc.Natl.Acad.Sci.USA, 110, 2013
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3WD4
| Serratia marcescens Chitinase B complexed with azide inhibitor and quinoline compound | 分子名称: | (E)-N-(prop-2-en-1-yloxy)-1-(quinolin-4-yl)methanimine, Chitinase B, GLYCEROL, ... | 著者 | Hirose, T, Maita, N, Gouda, H, Koseki, J, Yamamoto, T, Sugawara, A, Nakano, H, Hirono, S, Shiomi, K, Watanabe, T, Taniguchi, H, Sharpless, K.B, Omura, S, Sunazuka, T. | 登録日 | 2013-06-06 | 公開日 | 2013-09-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor Proc.Natl.Acad.Sci.USA, 110, 2013
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3WD2
| Serratia marcescens Chitinase B complexed with azide inhibitor | 分子名称: | Chitinase B, DITHIANE DIOL, GLYCEROL, ... | 著者 | Hirose, T, Maita, N, Gouda, H, Koseki, J, Yamamoto, T, Sugawara, A, Nakano, H, Hirono, S, Shiomi, K, Watanabe, T, Taniguchi, H, Sharpless, K.B, Omura, S, Sunazuka, T. | 登録日 | 2013-06-06 | 公開日 | 2013-09-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor Proc.Natl.Acad.Sci.USA, 110, 2013
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3WD1
| Serratia marcescens Chitinase B complexed with syn-triazole inhibitor | 分子名称: | Chitinase B, GLYCEROL, N,N-dibenzyl-N~5~-[N-(methylcarbamoyl)carbamimidoyl]-N~2~-{[5-({[(E)-(quinolin-4-ylmethylidene)amino]oxy}methyl)-1H-1,2,3-triazol-1-yl]acetyl}-L-ornithinamide, ... | 著者 | Hirose, T, Maita, N, Gouda, H, Koseki, J, Yamamoto, T, Sugawara, A, Nakano, H, Hirono, S, Shiomi, K, Watanabe, T, Taniguchi, H, Sharpless, K.B, Omura, S, Sunazuka, T. | 登録日 | 2013-06-06 | 公開日 | 2013-09-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor Proc.Natl.Acad.Sci.USA, 110, 2013
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3WD3
| Serratia marcescens Chitinase B complexed with azide inhibitor | 分子名称: | Chitinase B, GLYCEROL, SULFATE ION, ... | 著者 | Hirose, T, Maita, N, Gouda, H, Koseki, J, Yamamoto, T, Sugawara, A, Nakano, H, Hirono, S, Shiomi, K, Watanabe, T, Taniguchi, H, Sharpless, K.B, Omura, S, Sunazuka, T. | 登録日 | 2013-06-06 | 公開日 | 2013-09-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor Proc.Natl.Acad.Sci.USA, 110, 2013
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3WD0
| Serratia marcescens Chitinase B, tetragonal form | 分子名称: | Chitinase B, DITHIANE DIOL, GLYCEROL, ... | 著者 | Hirose, T, Maita, N, Gouda, H, Koseki, J, Yamamoto, T, Sugawara, A, Nakano, H, Hirono, S, Shiomi, K, Watanabe, T, Taniguchi, H, Sharpless, K.B, Omura, S, Sunazuka, T. | 登録日 | 2013-06-06 | 公開日 | 2013-09-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor Proc.Natl.Acad.Sci.USA, 110, 2013
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