1WSV

Crystal Structure of Human T-protein of Glycine Cleavage System

Summary for 1WSV

• Entry DOI: 10.2210/pdb1wsv/pdb
• Related: 1WSR
• Descriptor: Aminomethyltransferase, SULFATE ION, N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, ... (4 entities in total)
• Functional Keywords: glycine-cleavage sytem, aminomethyl transferase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion: P48728
• Total number of polymer chains: 2
• Total formula weight: 83832.04

Authors

Okamura-Ikeda, K.,Hosaka, H.,Yoshimura, M.,Yamashita, E.,Toma, S.,Nakagawa, A.,Fujiwara, K.,Motokawa, Y.,Taniguchi, H. (deposition date: 2004-11-11, release date: 2005-08-16, Last modification date: 2023-10-25)

• Primary citation: Okamura-Ikeda, K.,Hosaka, H.,Yoshimura, M.,Yamashita, E.,Toma, S.,Nakagawa, A.,Fujiwara, K.,Motokawa, Y.,Taniguchi, H.; Crystal Structure of Human T-protein of Glycine Cleavage System at 2.0A Resolution and its Implication for Understanding Non-ketotic Hyperglycinemia; J.Mol.Biol., 351:1146-1159, 2005; PubMed: 16051266; DOI: 10.1016/j.jmb.2005.06.056

Experimental method

X-RAY DIFFRACTION (2.6 Å)