3W82

Human alpha-L-iduronidase in complex with iduronic acid

Summary for 3W82

• Entry DOI: 10.2210/pdb3w82/pdb
• Related: 3W81
• Descriptor: Alpha-L-iduronidase, L(+)-TARTARIC ACID, PHOSPHITE ION, ... (12 entities in total)
• Functional Keywords: tim barrel, glycosyl hydrolase, glycosylation, lysosome, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Lysosome: P35475
• Total number of polymer chains: 2
• Total formula weight: 146064.51

Authors

Maita, N.,Tsukimura, T.,Taniguchi, T.,Saito, S.,Ohno, K.,Taniguchi, H.,Sakuraba, H. (deposition date: 2013-03-11, release date: 2013-08-21, Last modification date: 2023-11-08)

• Primary citation: Maita, N.,Tsukimura, T.,Taniguchi, T.,Saito, S.,Ohno, K.,Taniguchi, H.,Sakuraba, H.; Human alpha-L-iduronidase uses its own N-glycan as a substrate-binding and catalytic module; Proc.Natl.Acad.Sci.USA, 110:14628-14633, 2013; PubMed: 23959878; DOI: 10.1073/pnas.1306939110

Experimental method

X-RAY DIFFRACTION (2.76 Å)