3W82

Human alpha-L-iduronidase in complex with iduronic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Alpha-L-iduronidase	polymer	627	70123.4	2	UniProt (P35475) Pfam (PF01229) Pfam (PF21200) In PDB	Homo sapiens (human)
2	C	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1721.5	1	In PDB GlyTouCan (G89864BN)
3	D, G	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	E	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1559.4	1	In PDB GlyTouCan (G83161QT)
5	F	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G86851RC)
6	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7	A, B	alpha-L-idopyranuronic acid	non-polymer		194.1	2	Chemie (IDR)
8	A, B	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
9	A, B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
10	B	L(+)-TARTARIC ACID	non-polymer		150.1	1	Chemie (TLA)
11	B	PHOSPHITE ION	non-polymer		79.0	1	Chemie (PO3)
12		water	water		18.0	81	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	140246.8
Branched	Number of molecules	5
	Total formula weight	4497.1
Non-Polymers*	Number of molecules	10
	Total formula weight	1320.6
All*	Total formula weight	146064.5

*Water molecules are not included.