8PSM
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![BU of 8psm by Molmil](/molmil-images/mine/8psm) | Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the malonyl/palmitoyl transferase domain (FASx sample) | 分子名称: | 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PS1
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![BU of 8ps1 by Molmil](/molmil-images/mine/8ps1) | Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the ketosynthase domain (FASamn sample) | 分子名称: | COENZYME A, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PRV
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![BU of 8prv by Molmil](/molmil-images/mine/8prv) | Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the ketosreductase domain (FASamn sample) | 分子名称: | COENZYME A, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-12 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PS8
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![BU of 8ps8 by Molmil](/molmil-images/mine/8ps8) | Asymmetric unit of the yeast fatty acid synthase in the semi non-rotated state with ACP at the enoyl reductase domain (FASam sample) | 分子名称: | Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-26 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PSL
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![BU of 8psl by Molmil](/molmil-images/mine/8psl) | Asymmetric unit of the yeast fatty acid synthase in the semi non-rotated state with ACP at the ketosynthase domain (FASx sample) | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PSF
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![BU of 8psf by Molmil](/molmil-images/mine/8psf) | Asymmetric unit of the yeast fatty acid synthase in non-rotated state with ACP at the acetyl transferase domain (FASx sample) | 分子名称: | 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PS2
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![BU of 8ps2 by Molmil](/molmil-images/mine/8ps2) | Asymmetric unit of the yeast fatty acid synthase with ACP at the enoyl reductase domain (FASam sample) | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PSK
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![BU of 8psk by Molmil](/molmil-images/mine/8psk) | Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the ketosynthase domain (FASx sample) | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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5AFI
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![BU of 5afi by Molmil](/molmil-images/mine/5afi) | 2.9A Structure of E. coli ribosome-EF-TU complex by cs-corrected cryo-EM | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Fischer, N, Neumann, P, Konevega, A.L, Bock, L.V, Ficner, R, Rodnina, M.V, Stark, H. | 登録日 | 2015-01-22 | 公開日 | 2015-03-11 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure of the E. coli ribosome-EF-Tu complex at <3 angstrom resolution by Cs-corrected cryo-EM. Nature, 520, 2015
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5KHU
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![BU of 5khu by Molmil](/molmil-images/mine/5khu) | Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | 著者 | Yamaguchi, M, VanderLinden, R, Dube, P, Stark, H, Schulman, B. | 登録日 | 2016-06-15 | 公開日 | 2016-09-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation. Mol.Cell, 63, 2016
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5KHR
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![BU of 5khr by Molmil](/molmil-images/mine/5khr) | Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with the E2 UBE2C/UBCH10 poised for ubiquitin ligation to substrate (APC/C-CDC20-substrate-UBE2C) | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | 著者 | VanderLinden, R, Yamaguchi, M, Dube, P, Haselbach, D, Stark, H, Schulman, B.A. | 登録日 | 2016-06-15 | 公開日 | 2016-08-24 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation. Mol.Cell, 63, 2016
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5L9U
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![BU of 5l9u by Molmil](/molmil-images/mine/5l9u) | Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | 著者 | Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A. | 登録日 | 2016-06-11 | 公開日 | 2016-09-14 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | 主引用文献 | Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell, 165, 2016
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5L9T
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![BU of 5l9t by Molmil](/molmil-images/mine/5l9t) | Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | 著者 | Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A. | 登録日 | 2016-06-11 | 公開日 | 2016-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | 主引用文献 | Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell, 165, 2016
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5LF4
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![BU of 5lf4 by Molmil](/molmil-images/mine/5lf4) | Human 20S proteasome complex with Delanzomib at 2.0 Angstrom | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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5LF6
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![BU of 5lf6 by Molmil](/molmil-images/mine/5lf6) | Human 20S proteasome complex with Z-LLY-ketoaldehyde at 2.1 Angstrom | 分子名称: | CHLORIDE ION, LLY-ketoaldehyde peptide, MAGNESIUM ION, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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5LEY
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![BU of 5ley by Molmil](/molmil-images/mine/5ley) | Human 20S proteasome complex with Oprozomib at 1.9 Angstrom | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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5LF7
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![BU of 5lf7 by Molmil](/molmil-images/mine/5lf7) | Human 20S proteasome complex with Ixazomib at 2.0 Angstrom | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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5LF0
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![BU of 5lf0 by Molmil](/molmil-images/mine/5lf0) | Human 20S proteasome complex with Epoxomicin at 2.4 Angstrom | 分子名称: | CHLORIDE ION, EPOXOMICIN (peptide inhibitor), MAGNESIUM ION, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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5LEX
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![BU of 5lex by Molmil](/molmil-images/mine/5lex) | Native human 20S proteasome in Mg-Acetate at 2.2 Angstrom | 分子名称: | MAGNESIUM ION, PENTAETHYLENE GLYCOL, POTASSIUM ION, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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5LE5
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![BU of 5le5 by Molmil](/molmil-images/mine/5le5) | Native human 20S proteasome at 1.8 Angstrom | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-29 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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5LF3
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![BU of 5lf3 by Molmil](/molmil-images/mine/5lf3) | Human 20S proteasome complex with Bortezomib at 2.1 Angstrom | 分子名称: | CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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5LF1
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![BU of 5lf1 by Molmil](/molmil-images/mine/5lf1) | Human 20S proteasome complex with Dihydroeponemycin at 2.0 Angstrom | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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5M32
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![BU of 5m32 by Molmil](/molmil-images/mine/5m32) | Human 26S proteasome in complex with Oprozomib | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | 著者 | Haselbach, D, Schrader, J, Lambrecht, F, Henneberg, F, Chari, A, Stark, H. | 登録日 | 2016-10-14 | 公開日 | 2017-07-05 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nat Commun, 8, 2017
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5LEZ
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![BU of 5lez by Molmil](/molmil-images/mine/5lez) | Human 20S proteasome complex with Oprozomib in Mg-Acetate at 2.2 Angstrom | 分子名称: | ACETATE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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2MT5
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![BU of 2mt5 by Molmil](/molmil-images/mine/2mt5) | Isolated Ring domain | 分子名称: | Anaphase-promoting complex subunit 11, ZINC ION | 著者 | Brown, N.G, Watson, E.R, Weissman, F, Royappa, G, Schulman, B, Jarvis, M, Vanderlinden, R, Frye, J.J, Qiao, R, Petzold, G, Peters, J, Stark, H. | 登録日 | 2014-08-13 | 公開日 | 2014-10-29 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly. Mol.Cell, 56, 2014
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