2FK3
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2FJZ
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2FKL
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2FK1
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2FK2
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2FHE
| FASCIOLA HEPATICA GLUTATHIONE S-TRANSFERASE ISOFORM 1 IN COMPLEX WITH GLUTATHIONE | 分子名称: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE | 著者 | Polekhina, G, Rossjohn, J, Feil, S.C, Parker, M.W. | 登録日 | 1998-10-21 | 公開日 | 1998-10-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase. J.Mol.Biol., 273, 1997
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1K2F
| siah, Seven In Absentia Homolog | 分子名称: | BETA-MERCAPTOETHANOL, ZINC ION, siah-1A protein | 著者 | Polekhina, G, House, C.M, Traficante, N, Mackay, J.P, Relaix, F, Sassoon, D.A, Parker, M.W, Bowtell, D.D.L. | 登録日 | 2001-09-26 | 公開日 | 2001-12-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling. Nat.Struct.Biol., 9, 2002
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1KBN
| Glutathione transferase mutant | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, GLYCEROL, ... | 著者 | Rossjohn, J, Parker, M.W. | 登録日 | 2001-11-06 | 公開日 | 2003-11-11 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Glutathione transferase mutant To be Published
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4OJF
| Humanised 3D6 Fab complexed to amyloid beta 1-8 | 分子名称: | Amyloid beta A4 protein, Humanised 3D6 Fab Heavy Chain, Humanised 3D6 Fab Light Chain | 著者 | Miles, L.A, Crespi, G.A.N, Parker, M.W. | 登録日 | 2014-01-21 | 公開日 | 2015-01-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-beta ACTA CRYSTALLOGR.,SECT.F, 70, 2014
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6BFQ
| The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies | 分子名称: | Fab Heavy chain, Fab Light Chain, Granulocyte-macrophage colony-stimulating factor | 著者 | Dhagat, U, Hercus, T.R, Broughton, S.E, Nero, T.L, Lopez, A.F, Parker, M.W. | 登録日 | 2017-10-26 | 公開日 | 2018-09-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities. MAbs, 10, 2018
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1LBK
| Crystal structure of a recombinant glutathione transferase, created by replacing the last seven residues of each subunit of the human class pi isoenzyme with the additional C-terminal helix of human class alpha isoenzyme | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase class pi chimaera (CODA), ... | 著者 | Kong, G.K.W, Micaloni, C, Mazzetti, A.P, Nuccetelli, M, Antonini, G, Stella, L, McKinstry, W.J, Polekhina, G, Rossjohn, J, Federici, G, Ricci, G, Parker, M.W, Lo Bello, M. | 登録日 | 2002-04-04 | 公開日 | 2002-04-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences. J.Mol.Biol., 325, 2003
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1LJR
| GLUTATHIONE TRANSFERASE (HGST T2-2) FROM HUMAN | 分子名称: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE | 著者 | Rossjohn, J, Mckinstry, W.J, Oakley, A.J, Verger, D, Flanagan, J, Chelvanayagam, G, Tan, K.L, Board, P.G, Parker, M.W. | 登録日 | 1998-03-08 | 公開日 | 1999-03-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site. Structure, 6, 1998
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2AEW
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1MD4
| A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to valine | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase | 著者 | Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W. | 登録日 | 2002-08-06 | 公開日 | 2002-08-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1 J.Biol.Chem., 278, 2003
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3OVN
| Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase | 分子名称: | 1-methyl-3-(thiophen-2-yl)-1H-pyrazol-5-amine, CADMIUM ION, POL polyprotein, ... | 著者 | Wielens, J, Chalmers, D.K, Headey, S.J, Deadman, J.J, Rhodes, D.K, Parker, M.W, Scanlon, M.J. | 登録日 | 2010-09-16 | 公開日 | 2011-03-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
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3LJR
| GLUTATHIONE TRANSFERASE (THETA CLASS) FROM HUMAN IN COMPLEX WITH THE GLUTATHIONE CONJUGATE OF 1-MENAPHTHYL SULFATE | 分子名称: | 1-MENAPHTHYL GLUTATHIONE CONJUGATE, GLUTATHIONE S-TRANSFERASE, SULFATE ION | 著者 | Rossjohn, J, Mckinstry, W.J, Oakley, A.J, Verger, D, Flanagan, J, Chelvanayagam, G, Tan, K.L, Board, P.G, Parker, M.W. | 登録日 | 1998-03-08 | 公開日 | 1999-03-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site. Structure, 6, 1998
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3HA4
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2LJR
| GLUTATHIONE TRANSFERASE APO-FORM FROM HUMAN | 分子名称: | GLUTATHIONE S-TRANSFERASE | 著者 | Rossjohn, J, Mckinstry, W.J, Oakley, A.J, Verger, D, Flanagan, J, Chelvanayagam, G, Tan, K.L, Board, P.G, Parker, M.W. | 登録日 | 1998-03-08 | 公開日 | 1999-03-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site. Structure, 6, 1998
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2PMT
| GLUTATHIONE TRANSFERASE FROM PROTEUS MIRABILIS | 分子名称: | GLUTATHIONE, GLUTATHIONE TRANSFERASE | 著者 | Rossjohn, J, Polekhina, G, Feil, S.C, Allocati, N, Masulli, M, Diilio, C, Parker, M.W. | 登録日 | 1998-04-28 | 公開日 | 1999-04-27 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A mixed disulfide bond in bacterial glutathione transferase: functional and evolutionary implications. Structure, 6, 1998
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19GS
| Glutathione s-transferase p1-1 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,3'-(4,5,6,7-TETRABROMO-3-OXO-1(3H)-ISOBENZOFURANYLIDENE)BIS [6-HYDROXYBENZENESULFONIC ACID]ANION, GLUTATHIONE, ... | 著者 | Oakley, A.J, Lo Bello, M, Parker, M.W. | 登録日 | 1997-12-14 | 公開日 | 1998-12-30 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site). J.Mol.Biol., 291, 1999
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1A87
| COLICIN N | 分子名称: | COLICIN N | 著者 | Vetter, I.R, Parker, M.W, Tucker, A.D, Lakey, J.H, Pattus, F, Tsernoglou, D. | 登録日 | 1998-04-03 | 公開日 | 1999-04-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structure of a colicin N fragment suggests a model for toxicity. Structure, 6, 1998
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5DWU
| Beta common receptor in complex with a Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit beta, Fab - Heavy Chain, ... | 著者 | Dhagat, U, Parker, M.W. | 登録日 | 2015-09-23 | 公開日 | 2015-12-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.97 Å) | 主引用文献 | CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common beta chain of the IL-3, GM-CSF and IL-5 receptors. Mabs, 8, 2016
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3AKM
| X-ray structure of iFABP from human and rat with bound fluorescent fatty acid analogue | 分子名称: | 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid, Fatty acid-binding protein, intestinal, ... | 著者 | Wielens, J, Laguerre, A.J.K, Parker, M.W, Scanlon, M.J. | 登録日 | 2010-07-14 | 公開日 | 2011-07-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of human and rat intestinal fatty acid binding proteins in complex with 11-(Dansylamino)undecanoic acid To be Published
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3AKN
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3AO1
| Fragment-based approach to the design of ligands targeting a novel site in HIV-1 integrase | 分子名称: | 1,3-benzodioxol-5-ol, CADMIUM ION, POL polyprotein, ... | 著者 | Wielens, J, Parker, M.W, Chalmers, D.K, Scanlon, M.J. | 登録日 | 2010-09-17 | 公開日 | 2011-03-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
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