6HVM
 
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5AFI
 | | 2.9A Structure of E. coli ribosome-EF-TU complex by cs-corrected cryo-EM | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fischer, N, Neumann, P, Konevega, A.L, Bock, L.V, Ficner, R, Rodnina, M.V, Stark, H. | | 登録日 | 2015-01-22 | | 公開日 | 2015-03-11 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of the E. coli ribosome-EF-Tu complex at <3 angstrom resolution by Cs-corrected cryo-EM.
Nature, 520, 2015
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6HVL
 | | CdaA complex with c-di-AMP and AMP | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ADENOSINE MONOPHOSPHATE, COBALT (II) ION, ... | | 著者 | Heidemann, J.L, Neumann, P, Ficner, R. | | 登録日 | 2018-10-11 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of the c-di-AMP-synthesizing enzyme CdaA.
J.Biol.Chem., 294, 2019
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4B1T
 | | Structure of the factor Xa-like trypsin variant triple-Ala (TA) in complex with eglin C | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... | | 著者 | Menzel, A, Neumann, P, Stubbs, M.T. | | 登録日 | 2012-07-12 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Thermodynamic signatures in macromolecular interactions involving conformational flexibility.
Biol.Chem., 395, 2014
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4B2B
 | | Structure of the factor Xa-like trypsin variant triple-Ala (TGPA) in complex with eglin C | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... | | 著者 | Menzel, A, Neumann, P, Stubbs, M.T. | | 登録日 | 2012-07-13 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Thermodynamic signatures in macromolecular interactions involving conformational flexibility.
Biol.Chem., 395, 2014
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3L9B
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4B2C
 | | Structure of the factor Xa-like trypsin variant triple-Ala (TPA) in complex with eglin C | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... | | 著者 | Menzel, A, Neumann, P, Stubbs, M.T. | | 登録日 | 2012-07-13 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Thermodynamic signatures in macromolecular interactions involving conformational flexibility.
Biol.Chem., 395, 2014
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4B2A
 | | Structure of the factor Xa-like trypsin variant triple-Ala (TGA) in complex with eglin C | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... | | 著者 | Menzel, A, Neumann, P, Stubbs, M.T. | | 登録日 | 2012-07-13 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Thermodynamic signatures in macromolecular interactions involving conformational flexibility.
Biol.Chem., 395, 2014
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4NHO
 | | Structure of the spliceosomal DEAD-box protein Prp28 | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, MERCURY (II) ION, ... | | 著者 | Moehlmann, S, Neumann, P, Ficner, R. | | 登録日 | 2013-11-05 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28.
Acta Crystallogr.,Sect.D, 70, 2014
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7NZJ
 | | Structure of bsTrmB apo | | 分子名称: | GLYCEROL, SODIUM ION, tRNA (guanine-N(7)-)-methyltransferase | | 著者 | Blersch, K.F, Ficner, R, Neumann, P. | | 登録日 | 2021-03-24 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA.
Rna Biol., 18, 2021
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7NZI
 | | TrmB complex with SAH | | 分子名称: | GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(7)-)-methyltransferase | | 著者 | Blersch, K.F, Ficner, R, Neumann, P. | | 登録日 | 2021-03-24 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA.
Rna Biol., 18, 2021
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7NYB
 | | TrmB complex with SAM | | 分子名称: | S-ADENOSYLMETHIONINE, tRNA (guanine-N(7)-)-methyltransferase | | 著者 | Blersch, K.F, Ficner, R, Neumann, P. | | 登録日 | 2021-03-22 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA.
Rna Biol., 18, 2021
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2QC7
 | | Crystal structure of the protein-disulfide isomerase related chaperone ERp29 | | 分子名称: | Endoplasmic reticulum protein ERp29 | | 著者 | Barak, N.N, Sevvana, M, Neumann, P, Malesevic, M, Naumann, K, Fischer, G, Sheldrick, G.M, Stubbs, M.T, Ferrari, D.M. | | 登録日 | 2007-06-19 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure and functional analysis of the protein disulfide isomerase-related protein ERp29.
J.Mol.Biol., 385, 2009
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2QKH
 | | Crystal structure of the extracellular domain of human GIP receptor in complex with the hormone GIP | | 分子名称: | Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, D(-)-TARTARIC ACID, Glucose-dependent insulinotropic polypeptide, ... | | 著者 | Parthier, C, Kleinschmidt, M, Neumann, P, Rudolph, R, Manhart, S, Schlenzig, D, Fanghanel, J, Rahfeld, J.-U, Demuth, H.-U, Stubbs, M.T. | | 登録日 | 2007-07-11 | | 公開日 | 2007-08-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor
Proc.Natl.Acad.Sci.Usa, 104, 2007
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3E7W
 | | Crystal structure of DLTA: Implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains | | 分子名称: | ADENOSINE MONOPHOSPHATE, D-alanine--poly(phosphoribitol) ligase subunit 1, PHOSPHATE ION | | 著者 | Yonus, H, Neumann, P, Zimmermann, S, May, J.J, Marahiel, M.A, Stubbs, M.T. | | 登録日 | 2008-08-19 | | 公開日 | 2008-09-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains
J.Biol.Chem., 283, 2008
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3E7X
 | | Crystal structure of DLTA: implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains | | 分子名称: | ADENOSINE MONOPHOSPHATE, D-alanine--poly(phosphoribitol) ligase subunit 1 | | 著者 | Yonus, H, Neumann, P, Zimmermann, S, May, J.J, Marahiel, M.A, Stubbs, M.T. | | 登録日 | 2008-08-19 | | 公開日 | 2008-09-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains
J.Biol.Chem., 283, 2008
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6YJ8
 | | DarB-APO | | 分子名称: | ACETATE ION, CBS domain-containing protein YkuL, DI(HYDROXYETHYL)ETHER | | 著者 | Heidemann, J.L, Neumann, P, Ficner, R. | | 登録日 | 2020-04-02 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | DarB from B. subtilis
To Be Published
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6YJ9
 | | DarB in complex with 3'3'cGAMP | | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CBS domain-containing protein YkuL, CHLORIDE ION | | 著者 | Heidemann, J.L, Neumann, P, Ficner, R. | | 登録日 | 2020-04-02 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | DarB from B. subtilis
To Be Published
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6YJ7
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6YJA
 | | DarB fom B. subtilis in complex with c-di-AMP | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CALCIUM ION, CBS domain-containing protein YkuL, ... | | 著者 | Heidemann, J.L, Neumann, P, Ficner, R. | | 登録日 | 2020-04-02 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | DarB from B. subtilis
To Be Published
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1ICT
 | | MONOCLINIC FORM OF HUMAN TRANSTHYRETIN COMPLEXED WITH THYROXINE (T4) | | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN | | 著者 | Wojtczak, A, Neumann, P, Cody, V. | | 登録日 | 2001-04-02 | | 公開日 | 2002-04-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of a new polymorphic monoclinic form of human transthyretin at 3 A resolution reveals a mixed complex between unliganded and T4-bound tetramers of TTR.
Acta Crystallogr.,Sect.D, 57, 2001
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3GJX
 | | Crystal Structure of the Nuclear Export Complex CRM1-Snurportin1-RanGTP | | 分子名称: | CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... | | 著者 | Monecke, T, Guettler, T, Neumann, P, Dickmanns, A, Goerlich, D, Ficner, R. | | 登録日 | 2009-03-09 | | 公開日 | 2009-05-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP.
Science, 2009
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3E07
 | | Crystal structure of spatzle cystine knot | | 分子名称: | GLYCEROL, Protein spaetzle | | 著者 | Hoffmann, A, Funkner, A, Neumann, P, Juhnke, S, Walther, M, Schierhorn, A, Weininger, U, Balbach, J, Reuter, G, Stubbs, M.T. | | 登録日 | 2008-07-31 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Biophysical Characterization of Refolded Drosophila Spatzle, a Cystine Knot Protein, Reveals Distinct Properties of Three Isoforms
J.Biol.Chem., 283, 2008
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3EY6
 | | Crystal structure of the FK506-binding domain of human FKBP38 | | 分子名称: | FK506-binding protein 8 | | 著者 | Parthier, C, Maestre-Martinez, M, Neumann, P, Edlich, F, Fischer, G, Luecke, C, Stubbs, M.T. | | 登録日 | 2008-10-19 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding.
J.Mol.Recognit., 24, 2011
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6RMA
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | | 著者 | Hamann, F, Neumann, P, Ficner, R. | | 登録日 | 2019-05-06 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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