5V7I
 
 | | Crystal structure of homo sapiens serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), in complex with glycine, PLP and folate-competitive pyrazolopyran inhibitor: 6-amino-4-isopropyl-3-methyl-4-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | | 分子名称: | (4R)-6-amino-3-methyl-4-(propan-2-yl)-4-[3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Ducker, G.S, Ghergurovich, J.M, Mainolfi, N, Suri, V, Jeong, S, Friedman, A, Manfredi, M, Kim, H, Rabinowitz, J.D. | | 登録日 | 2017-03-20 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8I9Q
 | | The focused refinement of CCT4-PhLP2A from TRiC-PhLP2A complex in the open state | | 分子名称: | Phosducin-like protein 3, T-complex protein 1 subunit delta | | 著者 | Roh, S.H, Park, J, Kim, H, Lim, S. | | 登録日 | 2023-02-07 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | | 主引用文献 | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.
Nat Commun, 15, 2024
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8IB8
 | | Human TRiC-PhLP2A-actin complex in the closed state | | 分子名称: | ACTB protein (Fragment), Phosducin-like protein 3, T-complex protein 1 subunit alpha, ... | | 著者 | Roh, S.H, Park, J, Kim, H, Lim, S. | | 登録日 | 2023-02-09 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.42 Å) | | 主引用文献 | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.
Nat Commun, 15, 2024
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8I9U
 | | Human TRiC-PhLP2A complex in the open state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Phosducin-like protein 3, T-complex protein 1 subunit alpha, ... | | 著者 | Roh, S.H, Park, J, Kim, H, Lim, S. | | 登録日 | 2023-02-07 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.
Nat Commun, 15, 2024
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8I1U
 | | Human TRiC-PhLP2A complex in the closed state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | 著者 | Roh, S.H, Park, J, Kim, H, Lim, S. | | 登録日 | 2023-01-13 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.
Nat Commun, 15, 2024
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8I6J
 | | The focused refinement of CCT3-PhLP2A from TRiC-PhLP2A complex in the open state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Phosducin-like protein 3, T-complex protein 1 subunit gamma | | 著者 | Roh, S.H, Park, J, Kim, H, Lim, S. | | 登録日 | 2023-01-28 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | | 主引用文献 | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.
Nat Commun, 15, 2024
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2AD5
 | | Mechanisms of feedback regulation and drug resistance of CTP synthetases: structure of the E. coli CTPS/CTP complex at 2.8-Angstrom resolution. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Endrizzi, J.A, Kim, H, Anderson, P.M, Baldwin, E.P. | | 登録日 | 2005-07-19 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Mechanisms of Product Feedback Regulation and Drug Resistance in Cytidine Triphosphate Synthetases from the Structure of a CTP-Inhibited Complex(,).
Biochemistry, 44, 2005
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8X6M
 | | Crystal Structure of Glycerol Dehydrogenase in the Presence of NAD+ and Glycerol | | 分子名称: | GLYCEROL, Glycerol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Park, T, Kang, J.Y, Jin, M, Yang, J, Kim, H, Noh, C, Eom, S.H. | | 登録日 | 2023-11-21 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into the octamerization of glycerol dehydrogenase.
Plos One, 19, 2024
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2KEF
 | | Solution NMR structures of human hepcidin at 325K | | 分子名称: | Hepcidin | | 著者 | Jordan, J.B, Poppe, L, Hainu, M, Arvedson, T, Syed, R, Li, V, Kohno, H, Kim, H, Miranda, L.P, Cheetham, J, Sasu, B.J. | | 登録日 | 2009-01-29 | | 公開日 | 2009-06-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Hepcidin revisited, disulfide connectivity, dynamics, and structure.
J.Biol.Chem., 284, 2009
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3KYG
 | | Crystal structure of VCA0042 (L135R) complexed with c-di-GMP | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, Putative uncharacterized protein VCA0042 | | 著者 | Ryu, K.S, Ko, J, Kim, H, Choi, B.S. | | 登録日 | 2009-12-06 | | 公開日 | 2010-04-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of PP4397 Reveals the Molecular Basis for Different c-di-GMP Binding Modes by Pilz Domain Proteins.
J.Mol.Biol., 398, 2010
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1QCR
 | | CRYSTAL STRUCTURE OF BOVINE MITOCHONDRIAL CYTOCHROME BC1 COMPLEX, ALPHA CARBON ATOMS ONLY | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, UBIQUINOL CYTOCHROME C OXIDOREDUCTASE | | 著者 | Xia, D, Yu, C.A, Kim, H, Xia, J.Z, Kachurin, A, Zhang, L, Yu, L, Deisenhofer, J. | | 登録日 | 1997-05-17 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria.
Science, 277, 1997
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3GN4
 | | Myosin lever arm | | 分子名称: | CALCIUM ION, Calmodulin, MAGNESIUM ION, ... | | 著者 | Mukherjea, M, Llinas, P, Kim, H, Travaglia, M, Safer, D, Zong, A.B, Menetrey, J, Franzini-Armstrong, C, Selvin, P.R, Houdusse, A, Sweeney, H.L. | | 登録日 | 2009-03-16 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach
Mol.Cell, 35, 2009
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3KYF
 | | Crystal structure of P4397 complexed with c-di-GMP | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, Putative uncharacterized protein | | 著者 | Ryu, K.S, Ko, J, Kim, H, Choi, B.S. | | 登録日 | 2009-12-06 | | 公開日 | 2010-04-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of PP4397 Reveals the Molecular Basis for Different c-di-GMP Binding Modes by Pilz Domain Proteins.
J.Mol.Biol., 398, 2010
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6KF4
 | | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | | 分子名称: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... | | 著者 | Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. | | 登録日 | 2019-07-06 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | | 主引用文献 | Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
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7WBK
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7WBM
 | | Crystal structure of Legionella pneumophila effector protein Lpg0081 | | 分子名称: | Lpg0081, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | | 著者 | Lee, J, Kim, H, Oh, B.H. | | 登録日 | 2021-12-17 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Reversible modification of mitochondrial ADP/ATP translocases by paired Legionella effector proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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6AF2
 | | Crystal structure of N-terminus deletion mutant of Mycobacterium avium diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase | | 分子名称: | DI(HYDROXYETHYL)ETHER, HIT domain-containing protein, PENTAETHYLENE GLYCOL, ... | | 著者 | Mori, S, Honda, N, Kim, H, Rimbara, E, Shibayama, K. | | 登録日 | 2018-08-08 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | Crystal structure of N-terminus deletion mutant of Mycobacterium avium diadenosine tetraphosphate phosphorylase
To Be Published
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2ZFC
 | | X-ray crystal structure of an engineered N-terminal HIV-1 GP41 trimer with enhanced stability and potency | | 分子名称: | HIV-1 GP41 | | 著者 | Dwyer, J.J, Wilson, K.L, Martin, K, Seedorff, J.E, Hasan, A, Kim, H. | | 登録日 | 2007-12-29 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Design of an engineered N-terminal HIV-1 gp41 trimer with enhanced stability and potency
Protein Sci., 17, 2008
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2L1U
 | | Structure-Functional Analysis of Mammalian MsrB2 protein | | 分子名称: | Methionine-R-sulfoxide reductase B2, mitochondrial, ZINC ION | | 著者 | Aachmann, F.L, Del Conte, R, Kwak, G, Kim, H, Gladyshev, V.N, Dikiy, A. | | 登録日 | 2010-08-06 | | 公開日 | 2010-08-18 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure-Functional Analysis of Mammalian MsrB2 protein
To be Published
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1Y0Q
 | | Crystal structure of an active group I ribozyme-product complex | | 分子名称: | 5'-R(*GP*CP*UP*U)-3', Group I ribozyme, MAGNESIUM ION, ... | | 著者 | Golden, B.L, Kim, H, Chase, E. | | 登録日 | 2004-11-16 | | 公開日 | 2004-12-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Crystal structure of a phage Twort group I ribozyme-product complex
Nat.Struct.Mol.Biol., 12, 2005
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2K7W
 | | BAX Activation is Initiated at a Novel Interaction Site | | 分子名称: | Apoptosis regulator BAX, Bcl-2-like protein 11 | | 著者 | Gavathiotis, E, Suzuki, M, Davis, M.L, Pitter, K, Bird, G.H, Katz, S.G, Tu, H.C, Kim, H, Cheng, E.H, Tjandra, N, Walensky, L.D. | | 登録日 | 2008-08-27 | | 公開日 | 2008-10-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | BAX activation is initiated at a novel interaction site.
Nature, 455, 2008
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1PVR
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE LOXP (WILDTYPE) RECOGNITION SITE | | 分子名称: | 34-MER, Recombinase CRE | | 著者 | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | 登録日 | 2003-06-28 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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1PVQ
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 | | 分子名称: | DNA 34-MER, Recombinase cre | | 著者 | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | 登録日 | 2003-06-28 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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1PVP
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, ALSHG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 | | 分子名称: | 34-MER, Recombinase cre | | 著者 | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | 登録日 | 2003-06-28 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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5XD0
 | | Apo Structure of Beta-1,3-1,4-glucanase from Paenibacillus sp.X4 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Glucanase, TRIETHYLENE GLYCOL | | 著者 | Baek, S.C, Ho, T.-H, Kang, L.-W, Kim, H. | | 登録日 | 2017-03-24 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Improvement of enzyme activity of beta-1,3-1,4-glucanase from Paenibacillus sp. X4 by error-prone PCR and structural insights of mutated residues.
Appl. Microbiol. Biotechnol., 101, 2017
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