6KLK
 
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6L0I
 | | Crystal structure of dihydroorotase in complex with malate at pH6.5 from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil.
Biochem.Biophys.Res.Commun., 551, 2021
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6L0F
 | | Crystal structure of dihydroorotase in complex with 5-Aminouracil from Saccharomyces cerevisiae | | 分子名称: | 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.26 Å) | | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil.
Biochem.Biophys.Res.Commun., 551, 2021
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3FWL
 | | Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli | | 分子名称: | MOENOMYCIN, Penicillin-binding protein 1B | | 著者 | Sung, M.T, Lai, Y.T, Huang, C.Y, Chou, L.Y, Wong, C.H, Ma, C. | | 登録日 | 2009-01-19 | | 公開日 | 2009-06-02 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.086 Å) | | 主引用文献 | Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 106, 2009
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4APV
 | | The Klebsiella pneumoniae primosomal PriB protein: identification, crystal structure, and ssDNA binding mode | | 分子名称: | PRIMOSOMAL REPLICATION PROTEIN N | | 著者 | Lo, Y.H, Huang, Y.H, Hsiao, C.D, Huang, C.Y. | | 登録日 | 2012-04-06 | | 公開日 | 2012-04-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | | 主引用文献 | Crystal Structure and DNA-Binding Mode of Klebsiella Pneumoniae Primosomal Prib Protein.
Genes Cells, 17, 2012
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8GW0
 | | Crystal structure of the human dihydroorotase domain in complex with malic acid | | 分子名称: | (2S)-2-hydroxybutanedioic acid, CAD protein, ZINC ION | | 著者 | Yang, P.C, Liu, H.W, Huang, H.Y, Huang, C.Y. | | 登録日 | 2022-09-16 | | 公開日 | 2023-09-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil.
Biomolecules, 13, 2023
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8GW5
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8GVZ
 | | Crystal structure of the human dihydroorotase domain in complex with the anticancer drug 5-fluorouracil | | 分子名称: | 5-FLUOROURACIL, CAD protein, ZINC ION | | 著者 | Liu, H.W, Yang, P.C, Huang, H.Y, Huang, C.Y. | | 登録日 | 2022-09-16 | | 公開日 | 2023-09-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil.
Biomolecules, 13, 2023
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7CA0
 | | Crystal structure of dihydroorotase in complex with 5-fluoroorotic acid from Saccharomyces cerevisiae | | 分子名称: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2020-06-08 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode.
Bioinorg Chem Appl, 2021, 2021
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7CA1
 | | Crystal structure of dihydroorotase in complex with plumbagin from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, 5-hydroxy-2-methylnaphthalene-1,4-dione, Dihydroorotase, ... | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2020-06-08 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis.
Int J Mol Sci, 22, 2021
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7DEP
 | | S. aureus SsbB with 5-FU | | 分子名称: | 5-FLUOROURACIL, Single-stranded DNA-binding protein | | 著者 | Lin, E.S, Huang, Y.H, Huang, C.Y. | | 登録日 | 2020-11-04 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.094 Å) | | 主引用文献 | Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein
Biochem.Biophys.Res.Commun., 534, 2020
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5E5C
 | | Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 | | 分子名称: | D-hydantoinase/dihydropyrimidinase, ZINC ION | | 著者 | Huang, C.C, Huang, Y.H, Hsieh, Y.C, Tzeng, C.T, Chen, C.J, Huang, C.Y. | | 登録日 | 2015-10-08 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1: Insights into the molecular basis of formation of a dimer
Biochem.Biophys.Res.Commun., 478, 2016
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7AC4
 | | Structure of insulin collected by rotation serial crystallography on a COC membrane at a synchrotron source | | 分子名称: | Insulin, R-1,2-PROPANEDIOL, SODIUM ION | | 著者 | Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M. | | 登録日 | 2020-09-09 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
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7AC2
 | | Structure of Hen Egg White Lysozyme collected by rotation serial crystallography on a COC membrane at a synchrotron source | | 分子名称: | CHLORIDE ION, Lysozyme, SODIUM ION | | 著者 | Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M. | | 登録日 | 2020-09-09 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.507 Å) | | 主引用文献 | Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
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7AC3
 | | Structure of thaumatin collected by rotation serial crystallography on a COC membrane at a synchrotron source | | 分子名称: | L(+)-TARTARIC ACID, S-1,2-PROPANEDIOL, SODIUM ION, ... | | 著者 | Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M. | | 登録日 | 2020-09-09 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
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7AC6
 | | Structure of sponge-phase grown PepTst2 collected by rotation serial crystallography on a COC membrane at a synchrotron source | | 分子名称: | (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 2-(2-METHOXYETHOXY)ETHANOL, Di-or tripeptide:H+ symporter, ... | | 著者 | Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Wang, M, Marsh, M. | | 登録日 | 2020-09-10 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
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7AC5
 | | Structure of Tubulin Darpin complex 1 collected by rotation serial crystallography on a COC membrane at a synchrotron source | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Martiel, I, Olieric, N, Wranik, M, Padeste, C, Karpik, A, Huang, C.Y, Wang, M, Marsh, M. | | 登録日 | 2020-09-10 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
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7AI8
 | | Structure of Ribonucleotide reductase R2 from Escherichia coli collected by still serial crystallography on a COC membrane at a synchrotron source | | 分子名称: | FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta | | 著者 | Aurelius, O, John, J, Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Hogbom, M, Wang, M, Marsh, M. | | 登録日 | 2020-09-26 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
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7AI9
 | | Structure of Ribonucleotide reductase R2 from Escherichia coli collected by rotation serial crystallography on a COC membrane at a synchrotron source | | 分子名称: | FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta | | 著者 | Aurelius, O, John, J, Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Hogbom, M, Wang, M, Marsh, M. | | 登録日 | 2020-09-26 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
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5V54
 | | Crystal structure of 5-HT1B receptor in complex with methiothepin | | 分子名称: | 1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine, 5-hydroxytryptamine receptor 1B,OB-1 fused 5-HT1b receptor,5-hydroxytryptamine receptor 1B | | 著者 | Yin, W.C, Zhou, X.E, Yang, D, de Waal, P, Wang, M.T, Dai, A, Cai, X, Huang, C.Y, Liu, P, Yin, Y, Liu, B, Caffrey, M, Melcher, K, Xu, Y, Wang, M.W, Xu, H.E, Jiang, Y. | | 登録日 | 2017-03-13 | | 公開日 | 2018-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | A common antagonistic mechanism for class A GPCRs revealed by the structure of the human 5-HT1B serotonin receptor bound to an antagonist
Cell Discov, 2018
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5YYU
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2Q7Z
 | | Solution Structure of the 30 SCR domains of human Complement Receptor 1 | | 分子名称: | Complement receptor type 1 | | 著者 | Furtado, P.B, Huang, C.Y, Ihyembe, D, Hammond, R.A, Marsh, H.C, Perkins, S.J. | | 登録日 | 2007-06-08 | | 公開日 | 2007-10-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | The Partly Folded Back Solution Structure Arrangement of the 30 SCR Domains in Human Complement Receptor Type 1 (CR1) Permits Access to its C3b and C4b Ligands
J.Mol.Biol., 375, 2008
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6I59
 | | Long wavelength native-SAD phasing of Sen1 helicase | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Basu, S, Olieric, V, Matsugaki, N, Kawano, Y, Takashi, T, Huang, C.Y, Leonarski, F, Yamada, Y, Vera, L, Olieric, N, Basquin, J, Wojdyla, J.A, Diederichs, K, Yamamoto, M, Bunk, O, Wang, M. | | 登録日 | 2018-11-13 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
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6AEQ
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6AEP
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