1ZNI
 
 | | INSULIN | | 分子名称: | CHLORIDE ION, INSULIN, ZINC ION | | 著者 | Turkenburg, M.G.W, Whittingham, J.L, Dodson, G.G, Dodson, E.J, Xiao, B, Bentley, G.A. | | 登録日 | 1997-09-23 | | 公開日 | 1998-01-28 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.498 Å) | | 主引用文献 | Structure of insulin in 4-zinc insulin.
Nature, 261, 1976
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1FXW
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3H3E
 | | Crystal structure of Tm1679, A METAL-DEPENDENT HYDROLASE OF THE BETA-LACTAMASE SUPERFAMILY | | 分子名称: | ZINC ION, uncharacterized protein Tm1679 | | 著者 | Cooper, D.R, Olekhnovitch, N, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | | 登録日 | 2009-04-16 | | 公開日 | 2009-07-14 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (2.749 Å) | | 主引用文献 | Crystal structure of Tm1679, A METAL-DEPENDENT HYDROLASE OF THE BETA-LACTAMASE SUPERFAMILY
To be Published
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3BXQ
 | | The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition | | 分子名称: | ZINC ION, insulin A chain, insulin B chain | | 著者 | Wan, Z.L, Huang, K, Hu, S.Q, Whittaker, J, Weiss, M.A. | | 登録日 | 2008-01-14 | | 公開日 | 2008-05-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition.
J.Biol.Chem., 283, 2008
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3DT6
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3DT9
 | | Crystal Structure of Bovin Brain Platelet Activating Factor Acetylhydrolase Covalently Inhibited by Soman | | 分子名称: | (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE, Brain Platelet-activating factor acetylhydrolase IB subunit alpha | | 著者 | Epstein, T.M, Samanta, U, Bahnson, B.J. | | 登録日 | 2008-07-14 | | 公開日 | 2009-05-12 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin.
Biochemistry, 48, 2009
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3DT8
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7INS
 | | STRUCTURE OF PORCINE INSULIN COCRYSTALLIZED WITH CLUPEINE Z | | 分子名称: | GENERAL PROTAMINE CHAIN, INSULIN (CHAIN A), INSULIN (CHAIN B), ... | | 著者 | Balschmidt, P, Hansen, F.B, Dodson, E, Dodson, G, Korber, F. | | 登録日 | 1991-09-03 | | 公開日 | 1994-01-31 | | 最終更新日 | 2025-02-12 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of porcine insulin cocrystallized with clupeine Z.
Acta Crystallogr.,Sect.B, 47, 1991
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2TCI
 | | X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL | | 分子名称: | THIOCYANATE INSULIN, THIOCYANATE ION, ZINC ION | | 著者 | Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. | | 登録日 | 1995-09-13 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.
Biochemistry, 34, 1995
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1H4R
 | | Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein. | | 分子名称: | MERLIN, SULFATE ION | | 著者 | Cooper, D.R, Kang, B.S, Sheffield, P, Devedjiev, Y, Derewenda, Z.S. | | 登録日 | 2001-05-14 | | 公開日 | 2002-01-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product.
Acta Crystallogr.,Sect.D, 58, 2002
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3ZQD
 | | B. subtilis L,D-transpeptidase | | 分子名称: | L, D-TRANSPEPTIDASE YKUD | | 著者 | Lecoq, L, Simorre, J.-P, Bougault, C, Arthur, M, Hugonnet, J.-E, Veckerle, C, Pessey, O. | | 登録日 | 2011-06-09 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Dynamics Induced by Beta-Lactam Antibiotics in the Active Site of Bacillus subtilis L,D-Transpeptidase.
Structure, 20, 2012
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1YBO
 | | Crystal structure of the PDZ tandem of human syntenin with syndecan peptide | | 分子名称: | Syndecan-4, Syntenin 1 | | 著者 | Grembecka, J, Cooper, D.R, Cierpicki, T, Kang, B.S, Devedjiev, Y, Derewenda, Z. | | 登録日 | 2004-12-21 | | 公開日 | 2006-01-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The binding of the PDZ tandem of syntenin to target proteins
Biochemistry, 45, 2006
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1JFR
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3SXK
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3SXM
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3SXY
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3SXZ
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1C8U
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1W9Q
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEFAF peptide | | 分子名称: | BENZOIC ACID, SYNTENIN 1, TNEFAF PEPTIDE | | 著者 | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, Z.S. | | 登録日 | 2004-10-15 | | 公開日 | 2006-03-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
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1ES9
 | | X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH) | | 分子名称: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB GAMMA SUBUNIT | | 著者 | McMullen, T.W.P, Li, J, Sheffield, P.J, Aoki, J, Martin, T.W, Arai, H, Inoue, K, Derewenda, Z.S. | | 登録日 | 2000-04-07 | | 公開日 | 2000-05-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib).
Protein Eng., 13, 2000
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3GKY
 | | The Structural Basis of an ER Stress-Associated Bottleneck in a Protein Folding Landscape | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Liu, M, Wan, Z.L, Chu, Y.C, Alddin, H, Klaproth, B, Weiss, M.A. | | 登録日 | 2009-03-11 | | 公開日 | 2009-03-24 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of a "nonfoldable" insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY.
J.Biol.Chem., 284, 2009
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3KQ6
 | | Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Wan, Z.L, Hu, S.Q, Whittaker, L, Phillips, N.B, Whittake, J, Ismail-Beigi, F, Weiss, M.A. | | 登録日 | 2009-11-17 | | 公開日 | 2010-02-23 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Supramolecular protein engineering: design of zinc-stapled insulin hexamers as a long acting depot.
J.Biol.Chem., 285, 2010
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3MTH
 | | X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL | | 分子名称: | 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... | | 著者 | Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. | | 登録日 | 1995-09-13 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.
Biochemistry, 34, 1995
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3P2X
 | | Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity | | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | | 著者 | Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 2010-10-04 | | 公開日 | 2011-11-23 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published
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3P33
 | | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity | | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | | 著者 | Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 2010-10-04 | | 公開日 | 2011-11-23 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published
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