1ORB
 
 | | ACTIVE SITE STRUCTURAL FEATURES FOR CHEMICALLY MODIFIED FORMS OF RHODANESE | | 分子名称: | ACETATE ION, CARBOXYMETHYLATED RHODANESE | | 著者 | Gliubich, F, Gazerro, M, Zanotti, G, Delbono, S, Berni, R. | | 登録日 | 1995-07-24 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Active site structural features for chemically modified forms of rhodanese.
J.Biol.Chem., 271, 1996
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6R66
 | | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | | 分子名称: | 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Transthyretin | | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | 登録日 | 2019-03-26 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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6R68
 | | Crystal structure of transthyretin in complex with CHF4795, a flurbiprofen analogue | | 分子名称: | (2~{R})-2-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]propanoic acid, Transthyretin | | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | 登録日 | 2019-03-26 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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6R6I
 | | Crystal structure of transthyretin mutant A25T in complex with CHF5074, a flurbiprofen analogue | | 分子名称: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, PHOSPHATE ION, Transthyretin | | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | 登録日 | 2019-03-27 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.467 Å) | | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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6SUH
 | | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone, a tolcapone analogue | | 分子名称: | 3-O-methyltolcapone, Transthyretin | | 著者 | Loconte, V, Cianci, M, Menozzi, I, Sbravati, D, Sansone, F, Casnati, A, Berni, R. | | 登録日 | 2019-09-14 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Interactions of tolcapone analogues as stabilizers of the amyloidogenic protein transthyretin.
Bioorg.Chem., 103, 2020
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6SUG
 | | Crystal structure of transthyretin in complex with 3-deoxytolcapone, a tolcapone analogue | | 分子名称: | 3-deoxytolcapone, Transthyretin | | 著者 | Loconte, V, Cianci, M, Menozzi, I, Sbravati, D, Sansone, F, Casnati, A, Berni, R. | | 登録日 | 2019-09-14 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | | 主引用文献 | Interactions of tolcapone analogues as stabilizers of the amyloidogenic protein transthyretin.
Bioorg.Chem., 103, 2020
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6R67
 | | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | | 分子名称: | (2~{R})-2-[4-(3,5-dimethylphenyl)-3-fluoranyl-phenyl]propanoic acid, Transthyretin | | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | 登録日 | 2019-03-26 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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1HBQ
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1HBP
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1DP2
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1BRQ
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1BRP
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8C86
 | | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 2 | | 分子名称: | (2,4-dimethylphenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone, Transthyretin | | 著者 | Poonsiri, T, Benini, S, Loconte, V, Cianci, M. | | 登録日 | 2023-01-18 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity.
Int J Mol Sci, 25, 2023
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8C85
 | | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 1 | | 分子名称: | (3,5-dimethylphenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone, Transthyretin | | 著者 | Poonsiri, T, Benini, S, Loconte, V, Cianci, M. | | 登録日 | 2023-01-18 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity.
Int J Mol Sci, 25, 2023
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1RHS
 | | SULFUR-SUBSTITUTED RHODANESE | | 分子名称: | SULFUR-SUBSTITUTED RHODANESE | | 著者 | Zanotti, G, Gliubich, F, Colapietro, M, Barba, L. | | 登録日 | 1997-07-16 | | 公開日 | 1998-01-21 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Structure of sulfur-substituted rhodanese at 1.36 A resolution.
Acta Crystallogr.,Sect.D, 54, 1998
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1CRB
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1JYD
 | | Crystal Structure of Recombinant Human Serum Retinol-Binding Protein at 1.7 A Resolution | | 分子名称: | GLYCEROL, PLASMA RETINOL-BINDING PROTEIN | | 著者 | Greene, L.H, Chrysina, E.D, Irons, L.I, Papageorgiou, A.C, Acharya, K.R, Brew, K. | | 登録日 | 2001-09-12 | | 公開日 | 2003-07-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Role of conserved residues in structure and stability: Tryptophans of human serum
retinol-binding protein, a model for the lipocalin superfamily
Protein Sci., 10, 2001
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1JYJ
 | | Crystal Structure of a Double Variant (W67L/W91H) of Recombinant Human Serum Retinol-binding Protein at 2.0 A Resolution | | 分子名称: | GLYCEROL, PLASMA RETINOL-BINDING PROTEIN | | 著者 | Greene, L.H, Chrysina, E.D, Irons, L.I, Papageorgiou, A.C, Acharya, K.R, Brew, K. | | 登録日 | 2001-09-12 | | 公開日 | 2003-07-01 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Role of Conserved Residues in Structure and Stability: Tryptophans of Human Serum Retinol-Binding Protein, a Model for the Lipocalin Superfamily
Protein Sci., 10, 2001
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