6L15
 
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | | 分子名称: | 7-chloranyl-5-[3-[(3~{S})-piperidin-3-yl]propyl]pyrido[3,4-b][1,4]benzoxazine, Serine/threonine-protein kinase pim-1 | | 著者 | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | | 登録日 | 2019-09-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2020-07-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors.
J.Chem.Inf.Model., 60, 2020
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8GQD
 | | Complex Structure of Arginine Kinase McsB and McsA from Staphylococcus aureus | | 分子名称: | Protein-arginine kinase, Protein-arginine kinase activator protein, ZINC ION | | 著者 | Lu, K, Luo, B, Tao, X, Li, H, Xie, Y, Zhao, Z, Xia, W, Su, Z, Mao, Z. | | 登録日 | 2022-08-30 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Complex Structure and Activation Mechanism of Arginine Kinase McsB by McsA
To Be Published
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6KEV
 | | Reduced phosphoribulokinase from Synechococcus elongatus PCC 7942 complexed with adenosine diphosphate and glucose 6-phosphate | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 6-O-phosphono-alpha-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Yu, A, Xie, Y, Li, M. | | 登録日 | 2019-07-05 | | 公開日 | 2020-05-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.506139 Å) | | 主引用文献 | Photosynthetic Phosphoribulokinase Structures: Enzymatic Mechanisms and the Redox Regulation of the Calvin-Benson-Bassham Cycle.
Plant Cell, 32, 2020
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6KEZ
 | | Crystal structure of GAPDH/CP12/PRK complex from Arabidopsis thaliana | | 分子名称: | Calvin cycle protein CP12-2, Glyceraldehyde-3-phosphate dehydrogenase GAPA1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Yu, A, Xie, Y, Li, M. | | 登録日 | 2019-07-05 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Photosynthetic Phosphoribulokinase Structures: Enzymatic Mechanisms and the Redox Regulation of the Calvin-Benson-Bassham Cycle.
Plant Cell, 32, 2020
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6KEW
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6KEX
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7WDL
 | | Fungal immunomodulatory protein FIP-nha | | 分子名称: | Fungal immunomodulatory protein | | 著者 | Liu, Y, Bastiaan-Net, S, Zhang, Y, Hoppenbrouwers, T, Xie, Y, Wang, Y, Wei, X, Du, G, Zhang, H, Imam, K.M.S.U, Wichers, H.J, Li, Z. | | 登録日 | 2021-12-22 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | | 主引用文献 | Linking the thermostability of FIP-nha (Nectria haematococca) to its structural properties.
Int.J.Biol.Macromol., 213, 2022
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7VQ2
 | | Structure of Apo-hsTRPM2 channel TM domain | | 分子名称: | Transient receptor potential cation channel subfamily M member 2 | | 著者 | Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W. | | 登録日 | 2021-10-18 | | 公開日 | 2021-12-22 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.
Cell Rep, 37, 2021
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7VQ1
 | | Structure of Apo-hsTRPM2 channel | | 分子名称: | Transient receptor potential cation channel subfamily M member 2 | | 著者 | Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W. | | 登録日 | 2021-10-18 | | 公開日 | 2021-12-22 | | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | | 主引用文献 | Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.
Cell Rep, 37, 2021
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7XSV
 | | Crystal Structures of PIM1 in Complex with Macrocyclic Compound H3 | | 分子名称: | 8-Methyl-2,5,20-trioxa-8,13,17-triazatetracyclo[11.10.2.014,19.021,25]pentacosa-1(24),14(19),15,17,21(25),22-hexaene, Serine/threonine-protein kinase pim-1 | | 著者 | Shen, C, Xie, Y, Ren, X, Zhou, Y, Niu, H. | | 登録日 | 2022-05-15 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Design, synthesis, and bioactivity evaluation of macrocyclic benzo[b]pyrido[4,3-e][1,4]oxazine derivatives as novel Pim-1 kinase inhibitors.
Bioorg.Med.Chem.Lett., 72, 2022
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7WRH
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | | 著者 | Han, P, Xie, Y, Qi, J. | | 登録日 | 2022-01-26 | | 公開日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s.
Cell Discov, 8, 2022
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7WRI
 | | Cryo-EM structure of SARS-CoV-2 Omicron spike receptor-binding domain in complex with mouse ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein, ... | | 著者 | Han, P, Xie, Y, Qi, J. | | 登録日 | 2022-01-26 | | 公開日 | 2022-06-08 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s.
Cell Discov, 8, 2022
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7WRA
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7WRC
 | | Mouse TRPM8 in LMNG in the presence of calcium, icilin and PI(4,5)P2 | | 分子名称: | CALCIUM ION, Icilin, Transient receptor potential cation channel subfamily M member 8 | | 著者 | Zhao, C, Xie, Y, Guo, J. | | 登録日 | 2022-01-26 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structures of a mammalian TRPM8 in closed state.
Nat Commun, 13, 2022
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7WRB
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7WRE
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7WRD
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7WRF
 | | Mouse TRPM8 in lipid nanodiscs in the presence of calcium, icilin and PI(4,5)P2 | | 分子名称: | CALCIUM ION, Icilin, SODIUM ION, ... | | 著者 | Zhao, C, Xie, Y, Guo, J. | | 登録日 | 2022-01-26 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structures of a mammalian TRPM8 in closed state.
Nat Commun, 13, 2022
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6PNN
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6PNM
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6PNO
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6ABS
 | | Actin interacting protein 5 (Aip5, mutant) | | 分子名称: | Actin binding protein, PENTAETHYLENE GLYCOL, TRIETHYLENE GLYCOL | | 著者 | Sun, J, Ying, X, Toh, J, Hong, W, Miao, Y, Gao, Y.G. | | 登録日 | 2018-07-23 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization.
Nat Commun, 10, 2019
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7VKA
 | | Crystal Structure of GH3.6 in complex with an inhibitor | | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCEROL, Indole-3-acetic acid-amido synthetase GH3.6, ... | | 著者 | Wang, N, Luo, M, Bao, H, Huang, H. | | 登録日 | 2021-09-29 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Chemical genetic screening identifies nalacin as an inhibitor of GH3 amido synthetase for auxin conjugation.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7EQG
 | | Structure of Csy-AcrIF5 | | 分子名称: | AcrIF5, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | | 著者 | Zhang, L, Feng, Y. | | 登録日 | 2021-05-01 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition.
Nat.Chem.Biol., 18, 2022
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7F45
 | | Structure of an Anti-CRISPR protein | | 分子名称: | AcrIF5 | | 著者 | Feng, Y. | | 登録日 | 2021-06-17 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | | 主引用文献 | AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition.
Nat.Chem.Biol., 18, 2022
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